50-198-6474

Phospho-DDX58 (Thr170) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-6474-Each-of-1 In Stock ₹ 36,897.75

50-198-6474 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-DDX58 (Thr170)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; Probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; Retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

23586

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O95786

Gene Symbols

DDX58

Immunogen

KLH conjugated synthetic phosphopeptide derived from human DDX58 around the phosphorylation site of Thr170.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5′-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and ultimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

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Bioss

50-198-6474

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Antigen:
Phospho-DDX58 (Thr170)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; Probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; Retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23586

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O95786

Gene Symbols:
DDX58

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human DDX58 around the phosphorylation site of Thr170.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6475

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Antigen:
Phospho-Desmin (Thr17)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DES

Gene Alias:
BOS_2078; CMD1I; CSM1; CSM2; Des; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; mutant desmin p.K241E; SCPNK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1674

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P17661

Gene Symbols:
DES

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human DES around the phosphorylation site of Thr17.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6476

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Antigen:
Phospho-Desmin (Thr76, Thr77)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DES

Gene Alias:
BOS_2078; CMD1I; CSM1; CSM2; Des; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; mutant desmin p.K241E; SCPNK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1674

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P17661

Gene Symbols:
DES

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human DES around the phosphorylation site of Thr76/Thr77.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6477

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Antigen:
Phospho-Separase (Ser1073)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ESPL1

Gene Alias:
AL024103; AU045071; Caspase-like protein ESPL1; Cerp; Cut1/ESP1 related protein; ESP1; ESPL1; extra spindle pole bodies 1 (S. cerevisiae); extra spindle pole bodies 1, separase; extra spindle pole bodies homolog 1; extra spindle pole bodies like 1, separase; extra spindle poles like 1; Extra spindle poles-like 1 protein; FLJ46492; Kiaa0165; PRCE; SEPA; Separase; Separin; separin, cysteine protease; SSE

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9700

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q14674

Gene Symbols:
ESPL1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human ESPL1 around the phosphorylation site of Ser1073.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG