50-198-6500

Phospho-HER4 (Tyr1188) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-6500-Each-of-1 In Stock ₹ 36,897.75

50-198-6500 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-HER4 (Tyr1188)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERBB4

Gene Alias

4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; HER4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; Proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; Receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2066

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q15303

Gene Symbols

ERBB4

Immunogen

KLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1188.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • ErbB 4 (Her-4, c-erbB-4, v-erbB-4) is a member of the class I receptor kinase family
  • With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes
  • The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains
  • ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases)
  • ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself
  • Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
  • ErbB 4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum
  • Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361
  • Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
  • ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies.

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Bioss

50-198-6500

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Antigen:
Phospho-HER4 (Tyr1188)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; HER4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; Proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; Receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2066

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q15303

Gene Symbols:
ERBB4

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1188.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6502

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Antigen:
Phospho-E4B (Ser422)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Eif4b

Gene Alias:
2310046H11Rik; AL024095; BOS_5043; C85189; Eif4a2; EIF4B; eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609; LOC100354421; PRO1843

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1975

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P23588

Gene Symbols:
Eif4b

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human EIF4B around the phosphorylation site of Ser422.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6503

--


Antigen:
Phospho-E4B (Ser504)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Eif4b

Gene Alias:
2310046H11Rik; AL024095; BOS_5043; C85189; Eif4a2; EIF4B; eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609; LOC100354421; PRO1843

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1975

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P23588

Gene Symbols:
Eif4b

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human EIF4B around the phosphorylation site of Ser504.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6504

--


Antigen:
Phospho-E4G1 (Ser1238)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF4G1

Gene Alias:
BOS_1009; DKFZp686A1451; E030015G23Rik; EIF4F; EIF4G; eIF-4G 1; EIF4G1; eIF-4G1; EIF4-gamma; eIF-4-gamma 1; EIF4GI; eucaryotic translation initiation factor 4G; Eukaryotic translation initiation factor 4 gamma 1; eukaryotic translation initiation factor 4 gamma, 1; eukaryotic translation initiation factor 4, gamma 1; OTTHUMP00000210577; OTTHUMP00000210586; OTTHUMP00000210587; OTTHUMP00000210588; OTTHUMP00000210595; OTTHUMP00000210602; OTTHUMP00000210603; p220; PARK18

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1981

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q04637

Gene Symbols:
EIF4G1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human EIF4G1 around the phosphorylation site of Ser1238.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG