50-198-6567

Phospho-IKK beta S474 (Ser474) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-6567-Each-of-1 In Stock ₹ 36,897.75

50-198-6567 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-IKK beta S474 (Ser474)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ikbkb

Gene Alias

AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; IKBKB; IKK[b]; IKK2; IKK-2; Ikkb; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; Inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; Nuclear factor NF-kappa-B inhibitor kinase beta

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3551

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O14920

Gene Symbols

Ikbkb

Immunogen

KLH conjugated synthetic phosphopeptide derived from human IKK beta around the phosphorylation site of S474.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses
  • IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues
  • These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome
  • In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
  • Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).

Compare Similar Items

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Img

Bioss

50-198-6567

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Antigen:
Phospho-IKK beta S474 (Ser474)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; IKBKB; IKK[b]; IKK2; IKK-2; Ikkb; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; Inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; Nuclear factor NF-kappa-B inhibitor kinase beta

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3551

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O14920

Gene Symbols:
Ikbkb

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human IKK beta around the phosphorylation site of S474.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6569

--


Antigen:
Phospho-ILK-1 (Thr173)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ILK

Gene Alias:
59 kDa serine/threonine-protein kinase; AA511515; epididymis secretory protein Li 28; ESTM24; HEL-S-28; ILK; ILK1; ILK-1; ILK2; ILK-2; integrin binding protein kinase; integrin linked kinase; integrin-linked kinase; integrin-linked kinase-2; Integrin-linked protein kinase; loc; lost-contact; main squeeze; msq; P59; p59ILK; zgc:65842; zilk

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3611

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q13418

Gene Symbols:
ILK

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human ILK-1 around the phosphorylation site of Thr173.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6571

--


Antigen:
Phospho-IGF1R (Tyr980)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGF1R

Gene Alias:
A330103N21Rik; CD221; D930020L01; hyft; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3480

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P08069

Gene Symbols:
IGF1R

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr980.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6572

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Antigen:
Phospho-IGF1R (Tyr1165, Tyr1166)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGF1R

Gene Alias:
A330103N21Rik; CD221; D930020L01; hyft; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16001, 25718, 3480

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P08069, P24062, Q60751

Gene Symbols:
IGF1R

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr1165+Tyr1166.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG