50-198-7751

Perforin Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-7751-Each-of-1 In Stock ₹ 36,897.75

50-198-7751 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Perforin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRF1

Gene Alias

Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; Lymphocyte pore-forming protein; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; Perforin-1; Pfn; PFN1; Pfp; pore forming protein; PRF1; Prf-1; RATCYTA; RP11-710A11.3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5551

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P14222

Gene Symbols

PRF1

Immunogen

KLH conjugated synthetic peptide derived from human Perforin.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Perforin is one of the major cytolytic proteins of cytolytic granules
  • Perforin is a cytolytic mediator and is stored in and released by cytoplasmic granules
  • Moreover, perforin is involved in immune defense against tumors and virus infections as mediated by cytotoxic lymphocytes
  • Perforin is a 555 amino acid protein with a 21 amino acid signal peptide, and has a molecular weight of 70 to 75 kD
  • Perforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated
  • Studies show that perforin is expressed only in killer cell lines and not in helper T lymphocytes or other tumor cells tested
  • Perforin is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
  • Defects in the perforin gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood
  • Alternative splicing results in multiple transcript variants of perforin.

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Bioss

50-198-7751

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Antigen:
Perforin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRF1

Gene Alias:
Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; Lymphocyte pore-forming protein; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; Perforin-1; Pfn; PFN1; Pfp; pore forming protein; PRF1; Prf-1; RATCYTA; RP11-710A11.3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5551

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P14222

Gene Symbols:
PRF1

Immunogen:
KLH conjugated synthetic peptide derived from human Perforin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7754

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Antigen:
RRM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RRM2

Gene Alias:
AA407299; R2; ribonucleoside-diphosphate reductase M2 chain; Ribonucleoside-diphosphate reductase subunit M2; Ribonucleotide reductase 2; ribonucleotide reductase M2; ribonucleotide reductase M2 polypeptide; ribonucleotide reductase regulatory subunit M2; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit; RR2; RR2M; RRM2; RRR2M

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6241

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P31350

Gene Symbols:
RRM2

Immunogen:
KLH conjugated synthetic peptide derived from human RRM2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7755

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Antigen:
SPOP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPOP

Gene Alias:
AI315626; BTBD32; HIB homolog 1; Pcif1; PDX-1 C-terminal-interacting factor 1; Roadkill homolog 1; speckle type BTB/POZ protein; speckle type POZ protein; Speckle-type POZ protein; SPOP; TEF2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8405

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O43791

Gene Symbols:
SPOP

Immunogen:
KLH conjugated synthetic peptide derived from human SPOP.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7758

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Antigen:
ARHGEF18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Arhgef18

Gene Alias:
114 kDa Rho-specific guanine nucleotide exchange factor; AI467246; ARHGEF18; D030053O22Rik; Kiaa0521; p114RhoGEF; P114-RhoGEF; p114-Rho-GEF; Rho guanine nucleotide exchange factor 18; Rho/Rac guanine nucleotide exchange factor (GEF) 18; Rho/Rac guanine nucleotide exchange factor 18; Rho-specific guanine nucleotide exchange factor p114; SA-RhoGEF; Septin-associated RhoGEF

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23370

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q6ZSZ5

Gene Symbols:
Arhgef18

Immunogen:
KLH conjugated synthetic peptide derived from human ARHGEF18/p114RhoGEF.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG