50-198-7765

GSK3 Alpha + Beta Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-7765-Each-of-1 In Stock ₹ 36,897.75

50-198-7765 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

GSK3 Alpha + Beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GSK3A

Gene Alias

2700086H06Rik; 7330414F15Rik; 8430431H08Rik; C86142; FA; Factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; Glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 beta; GSK3; GSK-3; GSK-3 alpha; GSK-3 beta; Gsk3a; GSK3B; GSK-3beta; GSK3beta isoform; Serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2931, 2932, 50686, 56637, 606496, 84027

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P18265, P18266, P49840, P49841, Q2NL51, Q9WV60

Gene Symbols

GSK3A, GSK3B

Immunogen

KLH conjugated synthetic peptide derived from human GSK3 Alpha + Beta.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Glycogen synthase kinase-3 (GSK3) is a protein kinase that was originally identified as a regulator of glycogen synthase, a key enzyme in glycogen metabolism
  • Since then, it has been shown to be involved in the regulation of a diverse array of cellular functions, including protein synthesis, cell proliferation, cell differentiation, microtubule assembly/disassembly, and apoptosis
  • GSK3′s substrate specificity is unique in that phosphorylation of the substrate only occurs if a phosphoserine or phosphotyrosine is present - four residues C-terminal to the site of GSK phosphorylation
  • There exists two isoforms of GSK3, GSK3 alpha and GSK3 beta, and they are strictly regulated via phosphorylation
  • Phosphorylation of GSK3 beta on Ser9 (Ser21 in GSK3alpha) by protein kinase B (PKB) causes its inactivation and is the primary mechanism responsible for growth factor inhibition of this kinase
  • Activation of GSK3 beta is dependent upon the phosphorylation of Tyr216 (Tyr279 in GSK3 alpha)
  • Upon activation, it has been shown to phosphorylate a number of different cellular proteins, including p53, c-Myc, c-Jun, heat shock factor-1 (HSF-1), and cyclin D1
  • GSK3 beta also has been shown to phosphorylate aberrant sites on the microtubule associated protein tau, which is critical for the progression of Alzheimer′s disease.

Compare Similar Items

Show Difference

Img

Bioss

50-198-7765

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Antigen:
GSK3 Alpha + Beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GSK3A

Gene Alias:
2700086H06Rik; 7330414F15Rik; 8430431H08Rik; C86142; FA; Factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 beta; Glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 beta; GSK3; GSK-3; GSK-3 alpha; GSK-3 beta; Gsk3a; GSK3B; GSK-3beta; GSK3beta isoform; Serine/threonine-protein kinase GSK3A; Serine/threonine-protein kinase GSK3B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2931, 2932, 50686, 56637, 606496, 84027

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P18265, P18266, P49840, P49841, Q2NL51, Q9WV60

Gene Symbols:
GSK3A, GSK3B

Immunogen:
KLH conjugated synthetic peptide derived from human GSK3 Alpha + Beta.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7766

--


Antigen:
IL-17F

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL17F

Gene Alias:
C87042; CANDF6; Cytokine ML-1; Il17f; IL-17F; IL-24; ILN; Interleukin; interleukin 17F; Interleukin17F; Interleukin-17F; interleukin-24; ML1; ML-1; mutant IL-17F

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
112744

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q96PD4

Gene Symbols:
IL17F

Immunogen:
KLH conjugated synthetic peptide derived from mouse IL-17F.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7769

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Antigen:
Sumo 2+3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SUMO2

Gene Alias:
2810014B19Rik; D10Ertd345e; GMP1; HSMT3; I79_000932; MIF2 suppressor; Sentrin; sentrin 2; Sentrin-2; small ubiquitin-like modifier 2; small ubiquitin-like modifier 3; small ubiquitin-like modifier 3 L homeolog; Small ubiquitin-related modifier 2; Small ubiquitin-related modifier 3; Smt3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 homolog 2; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 2 (yeast); SMT3 suppressor of mif two 3 homolog 3; SMT3 suppressor of mif two 3 homolog 3 (yeast); SMT3 supressor of mif two 3 homolog 2; SMT3A; Smt3b; SMT3C; SMT3H1; SMT3H2; SMT3H3; SUMO-1; Sumo2; SUMO-2; sumo3; SUMO-3; sumo3.L; Ubiquitin-like protein SMT3A; Ubiquitin-like protein SMT3B; UBL1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
170930, 20610, 499417, 6612, 6613, 690244

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P55854, P61956, P61957, P61959, Q5XIF4, Q9Z172

Gene Symbols:
SUMO2, Sumo3

Immunogen:
KLH conjugated synthetic peptide derived from human Sumo 2+3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Bioworld

50-198-777

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