50-198-7896

DFFB Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-7896-Each-of-1 In Stock ₹ 36,897.75

50-198-7896 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

DFFB

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DFFB

Gene Alias

2410008J01Rik; 40kDa; 5730477D02Rik; AU018859; CAD; Caspase-activated deoxyribonuclease; caspase-activated DNase; Caspase-activated nuclease; Cpad; CPAN; DFF2; DFF-2; DFF40; DFF-40; Dffb; Didff; DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta subunit; DNase inhibited by DNA fragmentation factor; RP13-531C17.1; RP23-254N4.2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1677

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O76075

Gene Symbols

DFFB

Immunogen

KLH conjugated synthetic peptide derived from human DFFB.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Caspase-activated DNase (CAD) cleaves chromosomal DNA during apoptosis
  • Apoptosis which is a cell death process removing toxic and/or useless cells during mammalian development can be induced by a variety of stimuli, including the death factors of the tumor necrosis factor family, or UV irradiation, anticancer drugs, and survival factor deprivation
  • The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units
  • CAD, which can be activated by caspases, exists as a complex with its inhibitor, inhibitor of CAD (ICAD)
  • ICAD helps correct folding of CAD and remains complexed with CAD to inhibit the DNase activity of CAD
  • Caspase, which is activated during the apoptotic process, cleaves ICAD, and the CAD released from ICAD enters the nuclei to cleave the chromosomal DNA
  • Internal as well as external signals can activate caspases and this is under the control of the balance between pro-and anti-apoptotic proteins of the Bcl-2 family, heat shock proteins, and inhibitors of apoptosis proteins (IAPs)
  • Currently, fourteen members of the caspase family have been identified, of which seven mediate apoptosis.

Compare Similar Items

Show Difference

Img

Bioss

50-198-7896

--


Antigen:
DFFB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DFFB

Gene Alias:
2410008J01Rik; 40kDa; 5730477D02Rik; AU018859; CAD; Caspase-activated deoxyribonuclease; caspase-activated DNase; Caspase-activated nuclease; Cpad; CPAN; DFF2; DFF-2; DFF40; DFF-40; Dffb; Didff; DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase); DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, 40 kD, beta subunit; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta polypeptide (caspase-activated DNase); DNA fragmentation factor, beta subunit; DNase inhibited by DNA fragmentation factor; RP13-531C17.1; RP23-254N4.2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1677

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O76075

Gene Symbols:
DFFB

Immunogen:
KLH conjugated synthetic peptide derived from human DFFB.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7898

--


Antigen:
DNase 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNASE1

Gene Alias:
AI788650; Deoxyribonuclease 1; Deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; DNASE1; DNaseI; DNL 1; Dnl1; Dornase alfa; DRNI; FLJ38093; human urine deoxyribonuclease I

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1773

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P24855

Gene Symbols:
DNASE1

Immunogen:
KLH conjugated synthetic peptide derived from human DNase I.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7899

--


Antigen:
DNase 2 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNASE2

Gene Alias:
Acid DNase; Deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; Deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; Dnase2; Dnase2a; DNL; Dnl2; Lysosomal DNase II; R31240_2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1777

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O00115

Gene Symbols:
DNASE2

Immunogen:
KLH conjugated synthetic peptide derived from human DNase II alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7900

--


Antigen:
DNase gamma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNASE1L3

Gene Alias:
deoxyribonuclease 1-like 3; Deoxyribonuclease gamma; deoxyribonuclease I like 3; Deoxyribonuclease I-like 3; deoxyribonuclease I-like III; DHP2; DNAS1L3; DNase gamma; DNase I homolog protein 2; DNase I homolog protein DHP2; DNase I-like 3; DNASE1L3; DNasegamma; DNaseY; Liver and spleen DNase; Lsd; LS-DNase; macrophage specific DNase I; SLEB16

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1776

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q13609

Gene Symbols:
DNASE1L3

Immunogen:
KLH conjugated synthetic peptide derived from human DNase gamma.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG