50-198-7908

MDM4 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-7908-Each-of-1 In Stock ₹ 36,897.75

50-198-7908 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

MDM4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MDM4

Gene Alias

4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; Double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; Protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4194

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O15151

Gene Symbols

MDM4

Immunogen

KLH conjugated synthetic peptide derived from human MDM4.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • The MDM2 protein is the primary regulator of p53 protein stability
  • MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2
  • The gene that encodes MDMX (also designated MDM4) is a target for amplification in malignant gliomas
  • ARF interacts with MDMX to sequester MDMX within the nucleolus
  • This sequestration of MDMX by ARF results in an increase in p53 transactivation
  • In addition, expression of MDMX can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation
  • Like MDM2, MDMX also binds p73 and stabilizes the level of p73
  • Therefore, in striking contrast to p53, the half-life of p73 is increased by binding to MDM2.

Compare Similar Items

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Bioss

50-198-7908

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Antigen:
MDM4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MDM4

Gene Alias:
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; Double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; Protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4194

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O15151

Gene Symbols:
MDM4

Immunogen:
KLH conjugated synthetic peptide derived from human MDM4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7909

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Antigen:
TMUB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMUB1

Gene Alias:
C7orf21; Dendritic cell-derived ubiquitin-like protein; DULP; Hepatocyte odd protein shuttling protein; HOPS; iHOPS; SB144; TMUB1; transmembrane and ubiquitin like domain containing 1; transmembrane and ubiquitin-like domain containing 1; Transmembrane and ubiquitin-like domain-containing protein 1; ubiquitin-like protein DULP; Ubiquitin-like protein SB144; UNQ763/PRO1555

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
83590

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9BVT8

Gene Symbols:
TMUB1

Immunogen:
KLH conjugated synthetic peptide derived from human TMUB1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7910

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Antigen:
NUP50

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUP50

Gene Alias:
1700030K07Rik; 50 kDa nucleoporin; AI413123; BOS_6216; CTA-268H5.7; DKFZP564A043; LOC100359099; MGC39961; Npap60; NPAP60L; nuclear pore associated protein; nuclear pore associated protein 60 kDa; nuclear pore associated protein-like; Nuclear pore complex protein Nup50; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 50; nucleoporin 50 kDa; nucleoporin 50kD; nucleoporin 50kDa; Nucleoporin Nup50; nucleoprotein 50; Nucleoprotein 50kD; NUP50; NUP50 protein; OTTHUMP00000199530; PRO1146; Rtp60

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10762

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UKX7

Gene Symbols:
NUP50

Immunogen:
KLH conjugated synthetic peptide derived from human NUP50.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-7911

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Antigen:
PDCD2L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDCD2L

Gene Alias:
6030457N17Rik; MGC13096; Pdcd2l; programmed cell death 2 like; programmed cell death 2-like; Programmed cell death protein 2-like; RGD1308249

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
84306

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9BRP1

Gene Symbols:
PDCD2L

Immunogen:
KLH conjugated synthetic peptide derived from human PDCD2L/MGC13096.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG