50-198-8013

CDCA2 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-8013-Each-of-1 In Stock ₹ 36,897.75

50-198-8013 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

CDCA2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDCA2

Gene Alias

2610311M19Rik; AI586158; CDCA2; cell division cycle associated 2; Cell division cycle-associated protein 2; FLJ25804; MGC129906; MGC129907; PPP1R81; protein phosphatase 1, regulatory subunit 81; Recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

157313

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q69YH5

Gene Symbols

CDCA2

Immunogen

KLH conjugated synthetic peptide derived from human CDCA2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Cell division cycle associated 2 (CDCA2, Repo-Man) is a cell-cycle protein that recruits protein phosphatase 1 (PP1) to mitotic chromatin at anaphase onset, which is essential for cell proliferation
  • Carboxy-terminal phosphorylation of CDCA2 at Ser893 by Aurora B inhibits the protein and leads to diffuse localization during prometaphase and metaphase
  • Dephosphorylation of CDCA2 by PP2A is necessary for CDCA2/PP1 complex reformation
  • The CDCA2/PP1 complex is required for chromatin binding and dephosphorylation of histone H3 at Thr3, Ser10, and Ser28
  • The CDCA2/PP1 complex is also involved in nuclear envelope reformation during mitotic exit for proper progression through the M/G1 transition
  • The interaction of CDCA2 with importin beta and Nup153, which is required for nuclear envelope formation, is negatively regulated by CDK phosphorylation of the amino-terminal domain of CDCA2
  • CDCA2 may play a role in DNA repair as the release of CDCA2 from chromatin at sites of DNA damage promotes the activation of DNA damage response
  • These results imply that the CDCA2/PP1 complex may play a part in cancer progression
  • Research studies indicate that CDCA2 may serve as a prognostic marker, as increased CDCA2 expression is seen in a number of cancers, including melanoma, neuroblastoma tumors, squamous cell carcinoma, and synovial sarcomas.

Compare Similar Items

Show Difference

Img

Bioss

50-198-8013

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Antigen:
CDCA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDCA2

Gene Alias:
2610311M19Rik; AI586158; CDCA2; cell division cycle associated 2; Cell division cycle-associated protein 2; FLJ25804; MGC129906; MGC129907; PPP1R81; protein phosphatase 1, regulatory subunit 81; Recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
157313

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q69YH5

Gene Symbols:
CDCA2

Immunogen:
KLH conjugated synthetic peptide derived from human CDCA2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8014

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Antigen:
CEP152

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CEP152

Gene Alias:
AI851464; asterless; CC-CKR-8; CCR-8; CDw198; centrosomal protein 152; centrosomal protein 152kDa; Centrosomal protein of 152 kDa; Cep152; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; Kiaa0912; MCPH4; MCPH9; microcephaly, primary autosomal recessive 4; mKIAA0912; SCKL5; TER1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22995

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O94986

Gene Symbols:
CEP152

Immunogen:
KLH conjugated synthetic peptide derived from human CEP152.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8016

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Antigen:
CHMP1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CHMP1B

Gene Alias:
2810405I11Rik; BOS_22260; C10orf2; C18orf2; C18-ORF2; Charged multivesicular body protein 1b; Charged multivesicular body protein 1b-1; CHMP1.5; CHMP1.5 protein; Chmp1b; Chmp1b1; CHMP1b-1; chromatin modifying protein 1B; Chromatin-modifying protein 1b; Chromatin-modifying protein 1b-1; fb10c03; hVps46-2; hypothetical protein LOC336426; Similar to RIKEN cDNA 2810405I11 gene; vacuolar protein sorting 46-2; Vacuolar protein sorting-associated protein 46-2; Vps46-2; Vps46B; wu:fb10c03; zgc:56134

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
57132

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q7LBR1

Gene Symbols:
CHMP1B

Immunogen:
KLH conjugated synthetic peptide derived from human CHMP1B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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50-198-8017

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Antigen:
CIRBP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIRBP

Gene Alias:
A18 hnRNP; A18HNRNP; CIRBP; CIRP; cold inducible RNA binding protein; cold inducible RNA-binding protein; Cold-inducible RNA-binding protein; glycine-rich RNA binding protein; Glycine-rich RNA-binding protein CIRP; R74941; testicular tissue protein Li 39

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1153

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q14011

Gene Symbols:
CIRBP

Immunogen:
KLH conjugated synthetic peptide derived from human CIRBP.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG