50-198-8065

SKA2 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-8065-Each-of-1 In Stock ₹ 36,897.75

50-198-8065 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

SKA2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SKA2

Gene Alias

1110001A07Rik; C78640; Fam33a; family with sequence similarity 33, member A; Protein FAM33A; Ska2; spindle and kinetochore associated complex subunit 2; Spindle and kinetochore-associated protein 2; spindle and KT (kinetochore) associated 2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

348235

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q8WVK7

Gene Symbols

SKA2

Immunogen

KLH conjugated synthetic peptide derived from human SKA2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Upon entry into mitosis, the cell’s microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes
  • Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs
  • A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset
  • Depletion of either SKA1 or SKA2 by siRNA results in the loss of both proteins from the KT, but does not impact overall KT structure
  • Cells depleted of the SKA complex undergo a prolonged checkpoint-dependent delay in a metaphase-like state, indicating the importance of the SKA complex in the maintenance of the metaphase plate and spindle checkpoint silencing
  • SKA2 has also been shown to interact with glucocorticoid receptors and to be involved in glucocorticoid signaling and cell proliferation.

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Bioss

50-198-8065

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Antigen:
SKA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKA2

Gene Alias:
1110001A07Rik; C78640; Fam33a; family with sequence similarity 33, member A; Protein FAM33A; Ska2; spindle and kinetochore associated complex subunit 2; Spindle and kinetochore-associated protein 2; spindle and KT (kinetochore) associated 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
348235

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8WVK7

Gene Symbols:
SKA2

Immunogen:
KLH conjugated synthetic peptide derived from human SKA2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8066

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Antigen:
SKA3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKA3

Gene Alias:
C13orf3; F630043A04Rik; RAMA1; RGD1307201; RP11-101P17.12-002; Ska3; spindle and kinetochore associated complex subunit 3; Spindle and kinetochore-associated protein 3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
221150

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8IX90

Gene Symbols:
SKA3

Immunogen:
KLH conjugated synthetic peptide derived from human SKA3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8068

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Antigen:
MPS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPS27

Gene Alias:
3200001M24Rik; 40S ribosomal protein S27; metallopanstimulin 1; Metallopan-stimulin 1; MPS1; MPS-1; RGD:621045}; ribosomal protein S27; RP11-422P24.3; RPS27; rps27 {ECO:0000312; S27; S27-1; Small ribosomal subunit protein eS27

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6232

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P42677

Gene Symbols:
RPS27

Immunogen:
KLH conjugated synthetic peptide derived from human MPS1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8070

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Antigen:
ZWINT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZWINT

Gene Alias:
2010007E07Rik; 2600001N01Rik; D10Ertd749e; human ZW10 interacting protein-1; HZwint-1; KNTC2AP; neuroprotective protein 8; Scoilin; Sip30; SNAP25 interacting protein 30; SNAP25 interacting protein of 30 kDa; SNAP25-interacting protein 30; ZW10 interacting kinetochore protein; ZW10 interacting protein-1; ZW10 interactor; ZW10 interactor, kinetochore protein; ZW10-interacting protein 1; ZWINT; ZWINT1; Zwint-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11130

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O95229

Gene Symbols:
ZWINT

Immunogen:
KLH conjugated synthetic peptide derived from human ZWINT.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG