50-198-8119

Phospho-LATS1 (Thr1079) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-8119-Each-of-1 In Stock ₹ 36,897.75

50-198-8119 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-LATS1 (Thr1079)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LATS1

Gene Alias

AW208599; h-warts; large tumor suppressor; Large tumor suppressor homolog 1; large tumor suppressor kinase 1; large tumor supressor, homolog 1; LATS (large tumor suppressor, Drosophila) homolog 1; LATS, large tumor suppressor, homolog 1; Lats1; RGD1564085; Serine/threonine-protein kinase LATS1; WARTS; WARTS protein kinase; wts

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

9113

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O95835

Gene Symbols

LATS1

Immunogen

KLH conjugated synthetic phosphopeptide derived from human LATS1 around the phosphorylation site of Thr1079.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • LATS1 is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis
  • The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase
  • The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A
  • In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding
  • Biochemical and genetic data suggest a role as a tumor suppressor
  • This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.

Compare Similar Items

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Img

Bioss

50-198-8119

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Antigen:
Phospho-LATS1 (Thr1079)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LATS1

Gene Alias:
AW208599; h-warts; large tumor suppressor; Large tumor suppressor homolog 1; large tumor suppressor kinase 1; large tumor supressor, homolog 1; LATS (large tumor suppressor, Drosophila) homolog 1; LATS, large tumor suppressor, homolog 1; Lats1; RGD1564085; Serine/threonine-protein kinase LATS1; WARTS; WARTS protein kinase; wts

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9113

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O95835

Gene Symbols:
LATS1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human LATS1 around the phosphorylation site of Thr1079.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8120

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Antigen:
MOBKL2B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MOB3B

Gene Alias:
8430436F23Rik; A430018A01Rik; C9orf35; MOB kinase activator 3B; MOB kinase activator-like 2B; MOB1 (Mps One Binder) kinase activator-like 2B; Mob1 homolog 2b; MOB1, Mps One Binder kinase activator-like 2B; MOB1D; MOB3B; Mobkl2b; monopolar spindle 1 binding, MOB1, domain containing; Mps one binder kinase activator-like 2B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
79817

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q86TA1

Gene Symbols:
MOB3B

Immunogen:
KLH conjugated synthetic peptide derived from human MOBKL2B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8121

--


Antigen:
N acetylglucosamine kinase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NAGK

Gene Alias:
GlcNAc kinase; Gnk; HSA242910; N-acetyl-D-glucosamine kinase; N-acetylglucosamine kinase; Nagk

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55577

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UJ70

Gene Symbols:
NAGK

Immunogen:
KLH conjugated synthetic peptide derived from human N acetylglucosamine kinase.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8123

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Antigen:
PLK5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Plk5

Gene Alias:
6330514A18Rik; FG060302; Inactive serine/threonine-protein kinase PLK5; Plk5; PLK-5; PLK5P; polo like kinase 5; Polo-like kinase 5; polo-like kinase 5, pseudogene; serine/threonine-protein kinase PLK5; SgK384ps

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
126520

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q496M5

Gene Symbols:
Plk5

Immunogen:
KLH conjugated synthetic peptide derived from human PLK5.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG