50-198-8834

COPS8 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-8834-Each-of-1 In Stock ₹ 36,897.75

50-198-8834 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

COPS8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cops8

Gene Alias

9430009J09Rik; AA408242; COP9; COP9 (constitutive photomorphogenic) homolog, subunit 8; COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana); COP9 constitutive photomorphogenic homolog subunit 8; COP9 homolog; COP9 signalosome complex subunit 8; COP9 signalosome subunit 8; COPS8; CSN8; hCOP9; JAB1-containing signalosome subunit 8; SGN8; signalosome subunit 8

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10920

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q99627

Gene Symbols

Cops8

Immunogen

KLH conjugated synthetic peptide derived from human COPS8.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • COPS8 is a COP9 signalosome (CSN), which is an evolutionarily conserved protein complex of the eight subunits that interacts with deubiquitinating enzymes and protein kinases and is highly homologous to the lid sub-complex of 26S proteasome
  • The CSN complex is an essential regulator of the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-complexes such as SCF, CSA or DDB2
  • It is also involved in phosphorylation of p53, c-jun/JUN, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases
  • CSN8 encodes the smallest and the least conserved but first identified subunit of CSN
  • Recent studies show CSN8 is essential for Drosophila development and is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.

Compare Similar Items

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Img

Bioss

50-198-8834

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Antigen:
COPS8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cops8

Gene Alias:
9430009J09Rik; AA408242; COP9; COP9 (constitutive photomorphogenic) homolog, subunit 8; COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana); COP9 constitutive photomorphogenic homolog subunit 8; COP9 homolog; COP9 signalosome complex subunit 8; COP9 signalosome subunit 8; COPS8; CSN8; hCOP9; JAB1-containing signalosome subunit 8; SGN8; signalosome subunit 8

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10920

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q99627

Gene Symbols:
Cops8

Immunogen:
KLH conjugated synthetic peptide derived from human COPS8.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8835

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Antigen:
COPS6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COPS6

Gene Alias:
BOS_22974; COP9 (constitutive photomorphogenic) homolog, subunit 6; COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana); COP9 (constitutive photomorphogenic), subunit 6; COP9 complex S6; COP9 constitutive photomorphogenic homolog subunit 6; COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis); COP9 signalosome complex subunit 6; COP9 signalosome subunit 6; Cops6; CSN6; H_NH0506M12.12; HVIP; hypothetical protein LOC550465; JAB1-containing signalosome subunit 6; LOC100344111; MOV34 homolog; MOV34 homolog, 34 kD; MOV34-34KD; Sgn3; SGN6; signalosome subunit 6; VIP/MOV34; Vpr-interacting protein; zgc:112075

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10980

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q7L5N1

Gene Symbols:
COPS6

Immunogen:
KLH conjugated synthetic peptide derived from human COPS6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8836

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Antigen:
FBXO21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FBXO21

Gene Alias:
2810425J22Rik; AU016673; F-box only protein 21; F-box protein 21; FBX21; FBXO21; KIAA0875; mKIAA0875

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23014

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O94952

Gene Symbols:
FBXO21

Immunogen:
KLH conjugated synthetic peptide derived from human FBXO21.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8837

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Antigen:
FBXO38

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FBXO38

Gene Alias:
6030410I24Rik; AU044865; AW214031; F-box only protein 38; F-box protein 38; F-box protein modulating KLF7 activity; Fbx38; FBXO38; FLJ13962; HMN2D; Modulator of KLF7 activity; modulator of KLF7 activity homolog; MoKA; SP329

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
81545

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q6PIJ6

Gene Symbols:
FBXO38

Immunogen:
KLH conjugated synthetic peptide derived from human FBXO38.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG