50-198-8910

SERPINB3 + SERPINB4 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-8910-Each-of-1 In Stock ₹ 36,897.75

50-198-8910 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

SERPINB3 + SERPINB4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SERPINB4

Gene Alias

1110001H02Rik; 1110013A16Rik; HsT1196; Leupin; Peptidase inhibitor 11; PI11; PI-11; protease inhibitor (leucine-serpin); Protein T4-A; RGD1562868; SCC; SCCA; SCCA1; SCCA-1; SCCA2; SCCA-2; SCCA2/SCCA1 fusion protein; SCCA-PD; serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; serine peptidase inhibitor, clade B, member 3A; serine protease inhibitor B3; Serpin B3; Serpin B4; serpin family B member 3; serpin family B member 4; serpin peptidase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINB3; Serpinb3a; SERPINB4; Sqn5; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2; SSCA1; T4-A

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6317, 6318

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P29508, P48594

Gene Symbols

Serpinb3, SERPINB4

Immunogen

KLH conjugated synthetic peptide derived from human SERPINB3 (same as SERPINB4).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins
  • Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase
  • In 1985, Dr
  • Jim Travis and Dr
  • R.W
  • Carrell designated an emerging family of serine protease inhibitors as the serpin fam-ily, which share homology in both primary amino acid sequence and tertiary structure
  • Serpins contain a stretch of peptide that mimics a true substrate for a corresponding serine protease
  • Serine proteases bind to this substrate mimic in a 1:1 stoichiometric fashion and become catalytically inactive
  • Aberrant ex-pression of serpin family members can contribute to a number of conditions, including emphysema (a-1 antitrypsin deficiency), fatal bleeding (elastase to thrombin specificity) and thrombosis (antithrombin deficiency), and are indicators of cancer stage phenotypes (circulating levels of squamous cell carcinoma antigen, known as SCCA1, increase in advancing stages of some cervical, lung, esophageal and head and neck cancers)
  • Human chromosome position 18q21.3 contains a cluster of serpins, including a tandem duplication of the SCCA gene, plasminogen activator inhibitor type 2, and maspin
  • SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1
  • The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.

Compare Similar Items

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Img

Bioss

50-198-8910

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Antigen:
SERPINB3 + SERPINB4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SERPINB4

Gene Alias:
1110001H02Rik; 1110013A16Rik; HsT1196; Leupin; Peptidase inhibitor 11; PI11; PI-11; protease inhibitor (leucine-serpin); Protein T4-A; RGD1562868; SCC; SCCA; SCCA1; SCCA-1; SCCA2; SCCA-2; SCCA2/SCCA1 fusion protein; SCCA-PD; serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; serine peptidase inhibitor, clade B, member 3A; serine protease inhibitor B3; Serpin B3; Serpin B4; serpin family B member 3; serpin family B member 4; serpin peptidase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINB3; Serpinb3a; SERPINB4; Sqn5; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2; SSCA1; T4-A

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6317, 6318

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P29508, P48594

Gene Symbols:
Serpinb3, SERPINB4

Immunogen:
KLH conjugated synthetic peptide derived from human SERPINB3 (same as SERPINB4).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8911

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Antigen:
Cystatin D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CST5

Gene Alias:
CST5; CSTD; cystatin 5; cystatin D; Cystatin-5; Cystatin-D; cysteine-proteinase inhibitor; MGC71922

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1473

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P28325

Gene Symbols:
CST5

Immunogen:
KLH conjugated synthetic peptide derived from human Cystatin D.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8913

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Antigen:
CST9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CST9

Gene Alias:
CLM; CST9; CTES7A; cystatin 9; cystatin 9 (testatin); Cystatin-9; Cystatin-like molecule; testatin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
128822

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q5W186

Gene Symbols:
CST9

Immunogen:
KLH conjugated synthetic peptide derived from human CST9/Cystatin 9.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-8916

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Antigen:
C1orf187

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DRAXIN

Gene Alias:
2610109H07Rik; AGPA3119; C1orf187; Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; Draxin; FLJ34999; MGC117222; Neucrin; neural tissue-specific cysteine-rich protein; PSEC0258; UNQ3119; UNQ3119/PRO10268

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
374946

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8NBI3

Gene Symbols:
DRAXIN

Immunogen:
KLH conjugated synthetic peptide derived from human C1orf187.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG