50-198-8991
NHLRC1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-8991-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-8991 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
NHLRC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NHLRC1
Gene Alias
AI505271; B230309E09Rik; bA204B7.2; E3 ubiquitin-protein ligase NHLRC1; EPM2A; EPM2B; Malin; NHL repeat containing 1; NHL repeat containing E3 ubiquitin protein ligase 1; NHL repeat-containing protein 1; Nhlrc1; RING-type E3 ubiquitin transferase NHLRC1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
378884
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q6VVB1
Gene Symbols
NHLRC1
Immunogen
KLH conjugated synthetic peptide derived from human NHLRC1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Progressive myoclonic epilepsy type 2 (EPM2), also called Lafora disease, is an autosomal recessive disease characterized by grand mal seizures and/or myoclonus at about 15 years of age
- Rapid and severe mental deterioration follows, often with psychotic features
- Survival is less than 10 years after onset
- Starch-like, endoplasmic reticulum-associated polyglucosans, called Lafora bodies, can be observed in brain, muscle, liver and heart
- One cause of Lafora disease is due to mutations in NHLRC1, the gene encoding Malin
- Forty-nine different mutations in NHLRC1 have been shown to cause EPM2
- Malin, also called NHL repeat-containing protein 1, is a single subunit E3 ubiquitin ligase, containing 6 NHL repeats and 1 RING-type zinc finger
- Malin′s RING domain is responsible for its ability to mediate ubiquitination
- Malin interacts with and polyubiquitinates Laforin, a protein also implicated in EPM2
- Malin localizes to the endoplasmic reticulum and, to a lesser extent, in the nucleus
- Malin is expressed in brain, cerebellum, spinal cord, medulla, heart, liver, skeletal muscle and pancreas.
Compare Similar Items
Show Difference
Antigen: NHLRC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NHLRC1
Gene Alias: AI505271; B230309E09Rik; bA204B7.2; E3 ubiquitin-protein ligase NHLRC1; EPM2A; EPM2B; Malin; NHL repeat containing 1; NHL repeat containing E3 ubiquitin protein ligase 1; NHL repeat-containing protein 1; Nhlrc1; RING-type E3 ubiquitin transferase NHLRC1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 378884
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q6VVB1
Gene Symbols: NHLRC1
Immunogen: KLH conjugated synthetic peptide derived from human NHLRC1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NHLRC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NHLRC1
Gene Alias:
AI505271; B230309E09Rik; bA204B7.2; E3 ubiquitin-protein ligase NHLRC1; EPM2A; EPM2B; Malin; NHL repeat containing 1; NHL repeat containing E3 ubiquitin protein ligase 1; NHL repeat-containing protein 1; Nhlrc1; RING-type E3 ubiquitin transferase NHLRC1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
378884
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q6VVB1
Gene Symbols:
NHLRC1
Immunogen:
KLH conjugated synthetic peptide derived from human NHLRC1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NHLRC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NHLRC2
Gene Alias: 1200003G01Rik; NHL repeat containing 2; NHL repeat-containing protein 2; NHLRC2; novel NHL repeat domain containing protein
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 374354
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q8NBF2
Gene Symbols: NHLRC2
Immunogen: KLH conjugated synthetic peptide derived from human NHLRC2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NHLRC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NHLRC2
Gene Alias:
1200003G01Rik; NHL repeat containing 2; NHL repeat-containing protein 2; NHLRC2; novel NHL repeat domain containing protein
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
374354
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q8NBF2
Gene Symbols:
NHLRC2
Immunogen:
KLH conjugated synthetic peptide derived from human NHLRC2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NHLRC3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NHLRC3
Gene Alias: 4833441N19; 8030451K01Rik; BOS_12438; mKIAA4083; NHL repeat containing 3; NHL repeat-containing protein 3; Nhlrc3; RGD1565414
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 387921
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q5JS37
Gene Symbols: NHLRC3
Immunogen: KLH conjugated synthetic peptide derived from human NHLRC3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NHLRC3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NHLRC3
Gene Alias:
4833441N19; 8030451K01Rik; BOS_12438; mKIAA4083; NHL repeat containing 3; NHL repeat-containing protein 3; Nhlrc3; RGD1565414
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
387921
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q5JS37
Gene Symbols:
NHLRC3
Immunogen:
KLH conjugated synthetic peptide derived from human NHLRC3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MARCH2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Gene Alias: E3 ubiquitin-protein ligase MARCH2; March2; membrane associated ring-CH-type finger 2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: __
Gene Symbols: __
Immunogen: KLH conjugated synthetic peptide derived from human MARCH2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MARCH2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
E3 ubiquitin-protein ligase MARCH2; March2; membrane associated ring-CH-type finger 2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
KLH conjugated synthetic peptide derived from human MARCH2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG