50-198-9619
Phospho-IKB alpha (Ser32) Rabbit anti-Human, Clone: 13E7, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-9619-Each-of-1 | In Stock | ₹ 47,374.57 |
50-198-9619 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,374.57
GST (18%): ₹ 8,527.423
Total Price: ₹ 55,901.993
Antigen
Phospho-IKB alpha (Ser32)
Classification
Monoclonal
Concentration
1 μg/mL
Formulation
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.
P25963
Gene Symbols
NFKBIA
Immunogen
Synthetic peptide derived from human IKB alpha (Ser32) around 1-50 amino acids.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Western Blot
Clone
13E7
Conjugate
Unconjugated
Gene
NFKBIA
Gene Alias
AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4792
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
- The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
- The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
- A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
- These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
- In humans, the gene is located on the q arm of chromosome 14
- Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
- IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
- IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
- Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
- The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.
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Antigen: Phospho-IKB alpha (Ser32)
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: P25963
Gene Symbols: NFKBIA
Immunogen: Synthetic peptide derived from human IKB alpha (Ser32) around 1-50 amino acids.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Western Blot
Clone: 13E7
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4792
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-IKB alpha (Ser32)
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
P25963
Gene Symbols:
NFKBIA
Immunogen:
Synthetic peptide derived from human IKB alpha (Ser32) around 1-50 amino acids.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Western Blot
Clone:
13E7
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4792
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-p53 (Ser376)
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: P04637
Gene Symbols: Tp53
Immunogen: Synthetic peptide derived from human p53 (S376), around 350-400aa (phospho S376).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 7C9
Conjugate: Unconjugated
Gene: Tp53
Gene Alias: 53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7157
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-p53 (Ser376)
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
P04637
Gene Symbols:
Tp53
Immunogen:
Synthetic peptide derived from human p53 (S376), around 350-400aa (phospho S376).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
7C9
Conjugate:
Unconjugated
Gene:
Tp53
Gene Alias:
53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7157
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-PRKCA (Thr638)
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: P17252
Gene Symbols: PRKCA
Immunogen: Synthetic peptide derived from human PRKCA around PRKCA (Thr638) .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 4B3
Conjugate: Unconjugated
Gene: PRKCA
Gene Alias: AAG6; aging-associated gene 6; AI875142; BOS_19579; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; PKCA; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; PRKCA; prkcaa; protein kinase C alpha; Protein kinase C alpha type; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; protein kinase, C alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045)
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5578
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-PRKCA (Thr638)
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
P17252
Gene Symbols:
PRKCA
Immunogen:
Synthetic peptide derived from human PRKCA around PRKCA (Thr638) .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
4B3
Conjugate:
Unconjugated
Gene:
PRKCA
Gene Alias:
AAG6; aging-associated gene 6; AI875142; BOS_19579; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; PKCA; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; PRKCA; prkcaa; protein kinase C alpha; Protein kinase C alpha type; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; protein kinase, C alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045)
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5578
Content And Storage:
-20°C
Form:
Liquid
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