50-198-9653
Smad4 Rabbit anti-Human, Clone: 3A1, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-9653-Each-of-1 | In Stock | ₹ 47,374.57 |
50-198-9653 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,374.57
GST (18%): ₹ 8,527.423
Total Price: ₹ 55,901.993
Antigen
Smad4
Classification
Monoclonal
Concentration
1 μg/mL
Formulation
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.
Q13485
Gene Symbols
SMAD4
Immunogen
Recombinant human Smad4 protein, around N-terminal 1-200aa.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
3A1
Conjugate
Unconjugated
Gene
SMAD4
Gene Alias
AW743858; D18Wsu70e; deleted in pancreatic carcinoma locus 4; Deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; Dpc4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MADH4; Mothers against decapentaplegic homolog 4; mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; Smad4
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4089
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Smad4 is encoded by the Smad4 gene that is located on chromosome 18 in humans
- Smad4 is also known as Smad family member 4, Sma- and Mad-related protein 4 or Mothers against decapentaplegic (MAD) homolog 4
- Smad4 contains N-terminal MH1 (MAD homology 1) and C-terminal MH2 (MAD homology 2) globular domains that are involved in DNA binding and protein interactions respectively
- Binding of the TGF-beta superfamily of ligands that includes Transforming Growth Factor -beta (TGF-beta) and bone morphogenetic protein (BMP) to its cognate receptor allows phosphorylation of Smad 1, 2, 3, 5 and 8 (R-Smad, Receptor Smad)
- This signals for heterotrimerization with Smad4 (co-Smad, co-mediator Smad) and translocation of the complex to the nucleus
- Inhibitory or antagonistic Smad (I-Smad) that includes Smad 6 and 7, interact with activated R-Smads and attenuate the signaling pathway
- Smad4 acts as a tumor suppressor protein by transcriptionally regulating its target genes such as Cyclin D1 (downregulation) and collagen (upregulation) that inhibit cell proliferation
- Dephosphorylation regulates nuclear export and nucleocytoplasmic dynamics of Smads.
Compare Similar Items
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Antigen: Smad4
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: Q13485
Gene Symbols: SMAD4
Immunogen: Recombinant human Smad4 protein, around N-terminal 1-200aa.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 3A1
Conjugate: Unconjugated
Gene: SMAD4
Gene Alias: AW743858; D18Wsu70e; deleted in pancreatic carcinoma locus 4; Deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; Dpc4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MADH4; Mothers against decapentaplegic homolog 4; mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; Smad4
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4089
Content And Storage: -20°C
Form: Liquid
Antigen:
Smad4
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
Q13485
Gene Symbols:
SMAD4
Immunogen:
Recombinant human Smad4 protein, around N-terminal 1-200aa.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
3A1
Conjugate:
Unconjugated
Gene:
SMAD4
Gene Alias:
AW743858; D18Wsu70e; deleted in pancreatic carcinoma locus 4; Deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; Dpc4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MADH4; Mothers against decapentaplegic homolog 4; mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; Smad4
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4089
Content And Storage:
-20°C
Form:
Liquid
Antigen: STAT2
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: P52630
Gene Symbols: Stat2
Immunogen: Recombinant human STAT2 protein, around N-terminal 1-100aa.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: 4B1
Conjugate: Unconjugated
Gene: Stat2
Gene Alias: 1600010G07Rik; AW496480; BOS_5470; IMD44; interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; Signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; STAT; STAT 2; STAT113; STAT2; STAT-2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6773
Content And Storage: -20°C
Form: Liquid
Antigen:
STAT2
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
P52630
Gene Symbols:
Stat2
Immunogen:
Recombinant human STAT2 protein, around N-terminal 1-100aa.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
4B1
Conjugate:
Unconjugated
Gene:
Stat2
Gene Alias:
1600010G07Rik; AW496480; BOS_5470; IMD44; interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; Signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; STAT; STAT 2; STAT113; STAT2; STAT-2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6773
Content And Storage:
-20°C
Form:
Liquid
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Immunogen: __
Quantity: __
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
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Antigen:
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Classification:
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Concentration:
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Formulation:
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Gene Accession No.:
__
Gene Symbols:
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Immunogen:
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Quantity:
__
Primary or Secondary:
__
Target Species:
__
Product Type:
__
Isotype:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
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Host Species:
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Purification Method:
__
Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
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Form:
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Antigen: STAT5a
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.: P42229
Gene Symbols: STAT5A
Immunogen: Recombinant human STAT5a protein, around C-terminal 100aa.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 6E5
Conjugate: Unconjugated
Gene: STAT5A
Gene Alias: AA959963; BOS_19069; Mammary gland factor; mammary gland factor STAT5A; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5A; STAT; STAT5; Stat5a; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6776
Content And Storage: -20°C
Form: Liquid
Antigen:
STAT5a
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Accession No.:
P42229
Gene Symbols:
STAT5A
Immunogen:
Recombinant human STAT5a protein, around C-terminal 100aa.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
6E5
Conjugate:
Unconjugated
Gene:
STAT5A
Gene Alias:
AA959963; BOS_19069; Mammary gland factor; mammary gland factor STAT5A; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5A; STAT; STAT5; Stat5a; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6776
Content And Storage:
-20°C
Form:
Liquid