50-199-0036

p130 Rb2Rabbit anti-Human, Mouse, Rat, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-0036-Each-of-1 In Stock ₹ 50,884.24

50-199-0036 - Each of 1

₹ 50,884.24

In Stock

Quantity

1

Base Price: ₹ 50,884.24

GST (18%): ₹ 9,159.163

Total Price: ₹ 60,043.403

Antigen

p130 Rb2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RBL2

Gene Alias

130 kDa retinoblastoma-associated protein; FLJ26459; p130; PPAR-alpha-interacting complex protein 128; pRb2; PRIC128; RB transcriptional corepressor like 2; RB2; Rbl2; RBR-2; retinoblastoma-like 2; Retinoblastoma-like protein 2; Retinoblastoma-related protein 2

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Applications

ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

85 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

O55081, Q08999, Q64700

Gene Symbols

RBL2

Immunogen

Rb2 (p130) peptide corresponding to a region near the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory Status

RUO

Gene ID (Entrez)

19651, 5934, 81758

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Antiserum will specifically react with a 130 kDa Rb2 protein from human, rat and mouse tissue
  • No reaction was observed against other related tumor supressor proteins
  • Cross reactivity with Rb2 (p130) from other species may also occur
  • RBL2 (also known as p130) or Retinoblastoma-like protein 2 is a key regulator of entry into cell division
  • It is directly involved in heterochromatin formation by maintaining overall chromatin structure and (in particular) that of constitutive heterochromatin by stabilizing histone methylation
  • RBL2 recruits and targets histone methyltransferases KMT5B and KMT5C leading to epigenetic transcriptional repression
  • It controls histone H4 'Lys20' trimethylation
  • It probably also acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters
  • RBL2 serves as a potent inhibitor of E2F-mediated trans-activation and associates preferentially with E2F5.

Compare Similar Items

Show Difference

Img

Rockland Immunochemicals

50-199-0036

--


Antigen:
p130 Rb2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RBL2

Gene Alias:
130 kDa retinoblastoma-associated protein; FLJ26459; p130; PPAR-alpha-interacting complex protein 128; pRb2; PRIC128; RB transcriptional corepressor like 2; RB2; Rbl2; RBR-2; retinoblastoma-like 2; Retinoblastoma-like protein 2; Retinoblastoma-related protein 2

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
85 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O55081, Q08999, Q64700

Gene Symbols:
RBL2

Immunogen:
Rb2 (p130) peptide corresponding to a region near the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory Status:
RUO

Gene ID (Entrez):
19651, 5934, 81758

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0037

--


Antigen:
RFX5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RFX5

Gene Alias:
DNA-binding protein RFX5; Regulatory factor X 5; regulatory factor X, 5 (influences HLA class II expression); regulatory factor X5; RFX5; RP11-126K1.5

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Western Blot

Concentration:
90 mg/mL

Formulation:
Antibody with 0.01% sodium azide; pH

Gene Accession No.:
P48382

Gene Symbols:
RFX5

Immunogen:
RFX5 (C-terminal specific) peptide corresponding to a region near the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory Status:
RUO

Gene ID (Entrez):
5993

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0038

--


Antigen:
CIITA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIITA

Gene Alias:
C2ta; Ciita; CIITAIV; class II transactivator; class II, major histocompatibility complex, transactivator; EG669998; Gm9475; MH NLRA; MHC class II transactivator; MHC class II transactivator type I; MHC class II transactivator type III; MHC class II transactivator type IV; MHC2TA; NLR family, acid domain containing; NLRA; nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Western Blot

Concentration:
90 mg/mL

Formulation:
Antibody with 0.01% sodium azide; pH

Gene Accession No.:
P33076

Gene Symbols:
CIITA

Immunogen:
This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the N-terminal end of the human CIITA gene conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory Status:
RUO

Gene ID (Entrez):
4261

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0039

--


Antigen:
RFX5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RFX5

Gene Alias:
DNA-binding protein RFX5; Regulatory factor X 5; regulatory factor X, 5 (influences HLA class II expression); regulatory factor X5; RFX5; RP11-126K1.5

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Western Blot

Concentration:
90 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P48382

Gene Symbols:
RFX5

Immunogen:
RFX5 (N-terminal specific) peptide corresponding to a region near the N-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory Status:
RUO

Gene ID (Entrez):
5993

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid