50-199-0054

Smac/DiabloRabbit anti-Human, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

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Pack Size SKU Availability Price
Each of 1 50-199-0054-Each-of-1 In Stock ₹ 50,884.24

50-199-0054 - Each of 1

₹ 50,884.24

In Stock

Quantity

1

Base Price: ₹ 50,884.24

GST (18%): ₹ 9,159.163

Total Price: ₹ 60,043.403

Antigen

Smac/Diablo

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DIABLO

Gene Alias

0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); Diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; Direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; SMAC; Smac protein; SMAC3

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Immunoprecipitation, Western Blot

Concentration

85 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q9NR28

Gene Symbols

DIABLO

Immunogen

This whole rabbit serum was prepared by repeated immunizations with recombinant His6-tagged human Smac/DIABLO protein (amino acids 56-239).

Regulatory Status

RUO

Gene ID (Entrez)

56616

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antiserum is directed against human Smac/DIABLO and is useful in determining its presence in various assays
  • DIABLO (smac), a mitochondrial protein, activates various forms of apoptosis
  • This activation may be due to the neutralization of one or more members of the IAP family of apoptosis inhibitory proteins
  • Smac exits the mitochondria and enter the cytosol during certain apoptosis triggered events
  • Mitochondrial-mediated apoptosis is important in animal development and tissue homeostasis, with alterations resulting in a range of malignant disorders
  • Upon apoptotic stimuli, the mitochondrial proteins cytochrome c and Smac/DIABLO are released into the cytosol
  • The release of these proteins, however, occurs via different mechanisms
  • Smac/DIABLO has also been found to play a key role in regulating the sensitization of cancer cells to apoptosis (both immune and drug-induced).

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Rockland Immunochemicals

50-199-0054

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Antigen:
Smac/Diablo

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DIABLO

Gene Alias:
0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); Diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; Direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; SMAC; Smac protein; SMAC3

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
85 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q9NR28

Gene Symbols:
DIABLO

Immunogen:
This whole rabbit serum was prepared by repeated immunizations with recombinant His6-tagged human Smac/DIABLO protein (amino acids 56-239).

Regulatory Status:
RUO

Gene ID (Entrez):
56616

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0055

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Antigen:
CIITA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIITA

Gene Alias:
C2ta; Ciita; CIITAIV; class II transactivator; class II, major histocompatibility complex, transactivator; EG669998; Gm9475; MH NLRA; MHC class II transactivator; MHC class II transactivator type I; MHC class II transactivator type III; MHC class II transactivator type IV; MHC2TA; NLR family, acid domain containing; NLRA; nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
90 mg/mL

Formulation:
Antibody with 0.01% sodium azide; pH

Gene Accession No.:
P33076

Gene Symbols:
CIITA

Immunogen:
The immunogen used for this study was a bacterially produced recombinant FLAG-CIITA corresponding to amino acids 1 through 333 of the human protein.

Regulatory Status:
RUO

Gene ID (Entrez):
4261

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0056

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Antigen:
BIVM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BIVM

Gene Alias:
Basic immunoglobulin-like variable motif-containing protein; basic, immunoglobulin-like variable motif containing; BIVM; RP11-484I6.1

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
90 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q86UB2

Gene Symbols:
BIVM

Immunogen:
BIVM peptide corresponding to a region near carboxy terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory Status:
RUO

Gene ID (Entrez):
54841

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0058

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Antigen:
Phospho-NFkB (RelA) (Ser529)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RELA

Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; BOS_24973; EBP-1; I79_021812; MGC131774; NFkappaB p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NFKB1; Nfkb3; NFkB-p50; nuclear factor kappa B subunit p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; Putative transcription factor p65 homolog; rel1; Rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; XRel1; xrela

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
75 mg/mL

Formulation:
Antibody with 0.1% sodium azide; pH

Gene Accession No.:
Q04206

Gene Symbols:
RELA

Immunogen:
NFkB p65 (Rel A) peptide corresponding to a region near phospho Serine 529 of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory Status:
RUO

Gene ID (Entrez):
5970

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid