50-199-0185

IKB alphaRabbit anti-Human, Mouse, Rat, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

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Pack Size SKU Availability Price
Each of 1 50-199-0185-Each-of-1 In Stock ₹ 50,884.24

50-199-0185 - Each of 1

₹ 50,884.24

In Stock

Quantity

1

Base Price: ₹ 50,884.24

GST (18%): ₹ 9,159.163

Total Price: ₹ 60,043.403

Antigen

IKB alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NFKBIA

Gene Alias

AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Applications

ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

80 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2

Gene Accession No.

P25963, Q63746, Q9Z1E3

Gene Symbols

NFKBIA

Immunogen

IKB alpha Antibody was produced by repeated immunizations with a synthetic IkBa peptide corresponding to a region near the C-terminus of the human protein.

Regulatory Status

RUO

Gene ID (Entrez)

18035, 25493, 4792

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Anti- IkBa may react non-specifically with other proteins
  • Control peptide (code #100-4167P) will compete only with the specific reaction of antiserum with IkBa
  • IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
  • The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
  • The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
  • A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
  • These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
  • In humans, the gene is located on the q arm of chromosome 14
  • Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
  • IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
  • IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
  • Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
  • The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.

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Rockland Immunochemicals

50-199-0185

--


Antigen:
IKB alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NFKBIA

Gene Alias:
AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
80 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P25963, Q63746, Q9Z1E3

Gene Symbols:
NFKBIA

Immunogen:
IKB alpha Antibody was produced by repeated immunizations with a synthetic IkBa peptide corresponding to a region near the C-terminus of the human protein.

Regulatory Status:
RUO

Gene ID (Entrez):
18035, 25493, 4792

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0187

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Antigen:
Esterase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Rabbit

Quantity:
2 mL

Primary or Secondary:
Primary

Target Species:
Porcine

Product Type:
Antibody

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
85 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Esterase [Porcine Liver]

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Img

Rockland Immunochemicals

50-199-0189

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Antigen:
Lysozyme

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LYZ

Gene Alias:
1,4-beta-N-acetylmuramidase C; 1700038F02Rik; AI326280; bA534G20.1; c-type lysozyme; KAAG648; LYC2; Lys; Lysm; lysozyme; lysozyme (renal amyloidosis); lysozyme 1; lysozyme 2; Lysozyme C; Lysozyme C type M; Lysozyme C type P; Lysozyme C-1; Lysozyme C-2; lysozyme C-3; lysozyme d1; lysozyme F1; lysozyme like 1; lysozyme-like 1; Lysozyme-like protein 1; lysozyme-like protein 2; Lysz; Lyz; Lyz1; Lyz2; LYZD1; LYZF1; Lyzl1; Lyzs; LZM; Lzm-s1; Lzp; Lzp-s; P lysozyme structural; PRO1278; renal amyloidosis; RGD1559869; UNQ648/PRO1278

Host Species:
Rabbit

Quantity:
2 mL

Primary or Secondary:
Primary

Target Species:
Chicken

Product Type:
Antibody

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
80 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P00698

Gene Symbols:
LYZ

Immunogen:
Lysozyme [Hen Egg White]

Regulatory Status:
RUO

Gene ID (Entrez):
396218

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Img

Rockland Immunochemicals

50-199-0190

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Antigen:
Penicillinase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Beta lactamase; Oxacillinase

Host Species:
Rabbit

Quantity:
2 mL

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
90 mg/mL

Formulation:
0.01M sodium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Penicillinase [Enterobacter cloacae]

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized