50-199-1359

IL-17A Mouse anti-Human, Biotin, Clone: 4H1524.1, Rockland™

Manufacturer: Rockland Immunochemicals

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Pack Size SKU Availability Price
Each of 1 50-199-1359-Each-of-1 In Stock ₹ 52,903.46

50-199-1359 - Each of 1

₹ 52,903.46

In Stock

Quantity

1

Base Price: ₹ 52,903.46

GST (18%): ₹ 9,522.623

Total Price: ₹ 62,426.083

Antigen

IL-17A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q16552

Gene Symbols

IL17A

Immunogen

Anti-IL-17A (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17A produced in E.coli followed by hybridoma development.

Regulatory Status

RUO

Gene ID (Entrez)

3605

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

ELISA, Flow Cytometry, Western Blot

Clone

4H1524.1

Conjugate

Biotin

Gene

IL17A

Gene Alias

BOS_21471; CTLA8; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; IL17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17A-like; interleukin-17; Interleukin17A; Interleukin-17A; LOC100339322; R-IL-17-A

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Description

  • Store vial at 4°C prior to restoration
  • Restore with 0.1 mL of deionized water (or equivalent)
  • For extended storage aliquot contents and freeze at -20°C or below
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antibody is specific for human IL-17A protein
  • A BLAST analysis was used to suggest cross-reactivity with IL-17A from human sources based on 100% homology with the immunizing sequence
  • Cross-reactivity with IL-17A from other sources has not been determined
  • Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
  • IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
  • High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
  • In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
  • In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
  • Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
  • IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

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Rockland Immunochemicals

50-199-1359

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Antigen:
IL-17A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q16552

Gene Symbols:
IL17A

Immunogen:
Anti-IL-17A (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17A produced in E.coli followed by hybridoma development.

Regulatory Status:
RUO

Gene ID (Entrez):
3605

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
4H1524.1

Conjugate:
Biotin

Gene:
IL17A

Gene Alias:
BOS_21471; CTLA8; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; IL17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17A-like; interleukin-17; Interleukin17A; Interleukin-17A; LOC100339322; R-IL-17-A

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

Bioworld

50-199-136

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

Rockland Immunochemicals

50-199-1360

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Antigen:
MIP-3 alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P78556

Gene Symbols:
CCL20

Immunogen:
Anti-MIP-3alpha (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human MIP-3alpha produced in E.coli followed by hybridoma development.

Regulatory Status:
RUO

Gene ID (Entrez):
6364

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Clone:
3N2D9

Conjugate:
Biotin

Gene:
CCL20

Gene Alias:
beta chemokine exodus-1; Beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; C-C motif chemokine 20; C-C motif chemokine ligand 20; Ccl20; CCL20(1-64); CCL20(1-67); CCL20(2-70); chemokine (C-C motif) ligand 20; CKb4; Exodus; exodus-1; Larc; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 a; MIP 3alpha; MIP 3a; MIP3 a; MIP3 alpha; MIP3 a; MIP-3[a]; MIP3A; MIP-3a; MIP-3-alpha; M-MIP-3-alpha; SCYA20; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; Small-inducible cytokine A20; St38

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

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Rockland Immunochemicals

50-199-1361

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Antigen:
IL-17F

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q96PD4

Gene Symbols:
IL17F

Immunogen:
Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.

Regulatory Status:
RUO

Gene ID (Entrez):
112744

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Western Blot

Clone:
4H450.1

Conjugate:
Biotin

Gene:
IL17F

Gene Alias:
C87042; CANDF6; Cytokine ML-1; Il17f; IL-17F; IL-24; ILN; Interleukin; interleukin 17F; Interleukin17F; Interleukin-17F; interleukin-24; ML1; ML-1; mutant IL-17F

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1