50-199-1389

IL-35 EBI3Rabbit anti-Human, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

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Pack Size SKU Availability Price
Each of 1 50-199-1389-Each-of-1 In Stock ₹ 50,884.24

50-199-1389 - Each of 1

₹ 50,884.24

In Stock

Quantity

1

Base Price: ₹ 50,884.24

GST (18%): ₹ 9,159.163

Total Price: ₹ 60,043.403

Antigen

IL-35 EBI3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL27

Gene Alias

cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Western Blot

Concentration

1 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2

Gene Accession No.

Q14213, Q8NEV9

Gene Symbols

Ebi3, IL27

Immunogen

Anti-EBI-3 Antibody / Anti-IL27 is an IgG fraction antibody was prepared from rabbit antiserum after repeated immunizations with mature length recombinant human EBI3 protein produced in E.coli.

Regulatory Status

RUO

Gene ID (Entrez)

10148, 246778

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Description

  • Store vial at 4°C prior to restoration
  • For extended storage aliquot contents and freeze at -20°C or below
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Anti-EBI-3 Antibody / Anti-IL27 is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above
  • This antibody is specific for human EBI3 protein
  • A BLAST analysis was used to suggest cross-reactivity with EBI3 from human sources based on 100% homology with the immunizing sequence
  • Based on 97% homology, there is a chance of cross-reactivity to EBI3 from chimpanzee
  • Cross-reactivity with EBI-3 from other sources has not been determined
  • IL-27 (Interleukin 27) is a cytokine belonging to the IL-12 family, and is a heterodimeric cytokine composed of EBI3 and p28 subunits
  • IL-27 is produced by activated dendritic cells and macrophages in response to Toll-like receptor ligands and pro-inflammatory cytokines
  • IL-27 promotes CD4+ T cell differentiation to the Th1 lineage by inducing expression of the transcription factor T-bet and up regulating IL-12R beta2, which in turn suppresses Th2 and Th17 differentiation and proliferation
  • IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines
  • IL-27 acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting IL-27 involvement in the regulation of immune processes
  • It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet
  • In humans, the gene is located on the p arm of chromosome 16.

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Rockland Immunochemicals

50-199-1389

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Antigen:
IL-35 EBI3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL27

Gene Alias:
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2

Gene Accession No.:
Q14213, Q8NEV9

Gene Symbols:
Ebi3, IL27

Immunogen:
Anti-EBI-3 Antibody / Anti-IL27 is an IgG fraction antibody was prepared from rabbit antiserum after repeated immunizations with mature length recombinant human EBI3 protein produced in E.coli.

Regulatory Status:
RUO

Gene ID (Entrez):
10148, 246778

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

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Bioworld

50-199-139

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Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Img

Rockland Immunochemicals

50-199-1390

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Antigen:
IL-1 beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL1B

Gene Alias:
BOS_11619; Catabolin; IL 1ß; IL-1; IL1 B; IL-1 beta; Il1b; Il-1b; IL1beta; IL-1beta; IL1-BETA; IL1F2; IL1ß; ILN; Interleukin; interleukin 1 beta; interleukin 1, beta; Interleukin1 beta; Interleukin-1 beta; interleukin-1 beta proprotein; interleukin-1 beta-like; interleukin-beta; LOC100052414; Lymphocyte proliferation-potentiating factor; preinterleukin 1 beta; prointerleukin-1 beta; pro-interleukin-1-beta

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Non-human Primate

Product Type:
Antibody

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2

Gene Accession No.:
P01584, Q28292

Gene Symbols:
IL1B

Immunogen:
This antibody was prepared by repeated immunizations with recombinant human IL-1beta produced in E.coli. The MW of the recombinant 153 aa IL-1beta was 17 kDa with the N-terminal amino acid at position alanine 117. This cleavage site is generated by the IL-1beta converting enzyme (ICE, capase-1).

Regulatory Status:
RUO

Gene ID (Entrez):
3553, 403974

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Img

Rockland Immunochemicals

50-199-1391

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Antigen:
NAG-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gdf15

Gene Alias:
GDF15; GDF-15; growth differentiation factor 15; Growth/differentiation factor 15; macrophage inhibiting cytokine-1; Macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; Placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; Sbf

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
1.37 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q99988, Q9Z0J7

Gene Symbols:
Gdf15

Immunogen:
This Protein-A purified antibody was prepared by repeated immunizations with an MBP-tagged recombinant protein produced in E.coli corresponding to mature human NAG-1 protein. Cross reactivity to MBP was removed via cross-adsorption chromatography.

Regulatory Status:
RUO

Gene ID (Entrez):
23886, 9518

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid