50-199-1505

IL-17A Monoclonal Antibody (20B4.G10.F5), Rockland™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-199-1505-Each-of-1 In Stock ₹ 51,893.85

50-199-1505 - Each of 1

₹ 51,893.85

In Stock

Quantity

1

Base Price: ₹ 51,893.85

GST (18%): ₹ 9,340.893

Total Price: ₹ 61,234.743

Antigen

Mouse IL-17A

Classification

Monoclonal

Concentration

2.94 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q62386

Gene Symbols

IL17A

Immunogen

This Mouse IL-17A monoclonal antibody was produced in rats by repeated immunizations with full length recombinant mouse IL-17A protein (produced in E.coli) followed by hybridoma development.

Regulatory Status

RUO

Gene ID (Entrez)

16171

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Flow Cytometry, Western Blot

Clone

20B4.G10.F5

Conjugate

Unconjugated

Gene

IL17A

Gene Alias

BOS_21471; CTLA8; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; IL17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17A-like; interleukin-17; Interleukin17A; Interleukin-17A; LOC100339322; R-IL-17-A

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This monoclonal antibody is purified by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above
  • This antibody is specific for mouse IL-17A protein
  • Cross-reactivity with IL-17A from other sources has not been determined
  • Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
  • IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
  • High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
  • In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
  • In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
  • Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
  • IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

Compare Similar Items

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Img

Fischer Scientific

50-199-1505

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Antigen:
Mouse IL-17A

Classification:
Monoclonal

Concentration:
2.94 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q62386

Gene Symbols:
IL17A

Immunogen:
This Mouse IL-17A monoclonal antibody was produced in rats by repeated immunizations with full length recombinant mouse IL-17A protein (produced in E.coli) followed by hybridoma development.

Regulatory Status:
RUO

Gene ID (Entrez):
16171

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
20B4.G10.F5

Conjugate:
Unconjugated

Gene:
IL17A

Gene Alias:
BOS_21471; CTLA8; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; IL17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17A-like; interleukin-17; Interleukin17A; Interleukin-17A; LOC100339322; R-IL-17-A

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

50-199-1506

--


Antigen:
Mouse IL-17A

Classification:
Monoclonal

Concentration:
2.94 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q62386

Gene Symbols:
IL17A

Immunogen:
This Mouse IL-17A monoclonal antibody was produced in rats by repeated immunizations with full length recombinant mouse IL-17A protein (produced in E.coli) followed by hybridoma development.

Regulatory Status:
RUO

Gene ID (Entrez):
16171

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
20B4.G10.F5

Conjugate:
Unconjugated

Gene:
IL17A

Gene Alias:
BOS_21471; CTLA8; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; IL17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17A-like; interleukin-17; Interleukin17A; Interleukin-17A; LOC100339322; R-IL-17-A

Host Species:
Rat

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Fischer Scientific

50-199-1507

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Antigen:
MIP-3 alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O89093

Gene Symbols:
CCL20

Immunogen:
Anti-MIP-3alpha (RAT) Monoclonal Antibody was produced in rat by repeated immunizations with mature full length recombinant mouse MIP-3alpha produced in E.coli followed by hybridoma development.

Regulatory Status:
RUO

Gene ID (Entrez):
20297

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
4N5F7

Conjugate:
Unconjugated

Gene:
CCL20

Gene Alias:
beta chemokine exodus-1; Beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; C-C motif chemokine 20; C-C motif chemokine ligand 20; Ccl20; CCL20(1-64); CCL20(1-67); CCL20(2-70); chemokine (C-C motif) ligand 20; CKb4; Exodus; exodus-1; Larc; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 a; MIP 3alpha; MIP 3a; MIP3 a; MIP3 alpha; MIP3 a; MIP-3[a]; MIP3A; MIP-3a; MIP-3-alpha; M-MIP-3-alpha; SCYA20; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; Small-inducible cytokine A20; St38

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-1508

--


Antigen:
MIP-3 alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O89093

Gene Symbols:
CCL20

Immunogen:
Anti-MIP-3alpha (RAT) Monoclonal Antibody was produced in rat by repeated immunizations with mature full length recombinant mouse MIP-3alpha produced in E.coli followed by hybridoma development.

Regulatory Status:
RUO

Gene ID (Entrez):
20297

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Clone:
4N5F7

Conjugate:
Unconjugated

Gene:
CCL20

Gene Alias:
beta chemokine exodus-1; Beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; C-C motif chemokine 20; C-C motif chemokine ligand 20; Ccl20; CCL20(1-64); CCL20(1-67); CCL20(2-70); chemokine (C-C motif) ligand 20; CKb4; Exodus; exodus-1; Larc; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 a; MIP 3alpha; MIP 3a; MIP3 a; MIP3 alpha; MIP3 a; MIP-3[a]; MIP3A; MIP-3a; MIP-3-alpha; M-MIP-3-alpha; SCYA20; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; Small-inducible cytokine A20; St38

Host Species:
Rat

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG