50-199-1514

IL-35 EBI3 Rat anti-Mouse, Biotin, Clone: 10J811, Rockland™

Manufacturer: Rockland Immunochemicals

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Pack Size SKU Availability Price
Each of 1 50-199-1514-Each-of-1 In Stock ₹ 52,903.46

50-199-1514 - Each of 1

₹ 52,903.46

In Stock

Quantity

1

Base Price: ₹ 52,903.46

GST (18%): ₹ 9,522.623

Total Price: ₹ 62,426.083

Antigen

IL-35 EBI3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Accession No.

O35228, Q8K3I6

Gene Symbols

Ebi3, IL27

Immunogen

Anti-EBI-3 (RAT) Monoclonal Antibody was produced in rat by repeated immunizations with mature full length recombinant mouse EBI-3 produced in E.coli followed by hybridoma development.

Regulatory Status

RUO

Gene ID (Entrez)

246779, 50498

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

ELISA, Flow Cytometry, Western Blot

Clone

10J811

Conjugate

Biotin

Gene

IL27

Gene Alias

cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Store vial at 4°C prior to restoration
  • Restore with 0.1 mL of deionized water (or equivalent)
  • For extended storage aliquot contents and freeze at -20°C or below
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antibody is specific for mouse EBI3 protein
  • A BLAST analysis was used to suggest cross-reactivity with EBI3 from mouse sources based on 100% homology with the immunizing sequence
  • Cross-reactivity with EBI-3 from other sources has not been determined
  • IL-27 (Interleukin 27) is a cytokine belonging to the IL-12 family, and is a heterodimeric cytokine composed of EBI3 and p28 subunits
  • IL-27 is produced by activated dendritic cells and macrophages in response to Toll-like receptor ligands and pro-inflammatory cytokines
  • IL-27 promotes CD4+ T cell differentiation to the Th1 lineage by inducing expression of the transcription factor T-bet and up regulating IL-12R beta2, which in turn suppresses Th2 and Th17 differentiation and proliferation
  • IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines
  • IL-27 acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting IL-27 involvement in the regulation of immune processes
  • It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet
  • In humans, the gene is located on the p arm of chromosome 16.

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Rockland Immunochemicals

50-199-1514

--


Antigen:
IL-35 EBI3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O35228, Q8K3I6

Gene Symbols:
Ebi3, IL27

Immunogen:
Anti-EBI-3 (RAT) Monoclonal Antibody was produced in rat by repeated immunizations with mature full length recombinant mouse EBI-3 produced in E.coli followed by hybridoma development.

Regulatory Status:
RUO

Gene ID (Entrez):
246779, 50498

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
10J811

Conjugate:
Biotin

Gene:
IL27

Gene Alias:
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Rockland Immunochemicals

50-199-1517

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Antigen:
IL-17A

Classification:
Polyclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2

Gene Accession No.:
Q61453, Q62386

Gene Symbols:
IL17A

Immunogen:
This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant rat IL17-A protein.

Regulatory Status:
RUO

Gene ID (Entrez):
16171, 301289

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
IL17A

Gene Alias:
BOS_21471; CTLA8; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; IL17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17A-like; interleukin-17; Interleukin17A; Interleukin-17A; LOC100339322; R-IL-17-A

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
__

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Rockland Immunochemicals

50-199-1519

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Antigen:
IL-17A

Classification:
Polyclonal

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q61453, Q62386

Gene Symbols:
IL17A

Immunogen:
This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant rat IL17-A protein.

Regulatory Status:
RUO

Gene ID (Entrez):
16171, 301289

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
__

Conjugate:
Biotin

Gene:
IL17A

Gene Alias:
BOS_21471; CTLA8; CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; IL17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17A-like; interleukin-17; Interleukin17A; Interleukin-17A; LOC100339322; R-IL-17-A

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
__

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Bioworld

50-199-152

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__