50-199-1580
GRK2 Polyclonal Antibody, Rockland™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-1580-Each-of-1 | In Stock | ₹ 14,374.08 |
50-199-1580 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,374.08
GST (18%): ₹ 2,587.334
Total Price: ₹ 16,961.414
Antigen
GRK2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRK2
Gene Alias
Adrbk1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; Beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; GRK2; GRK-2
Host Species
Goat
Regulatory Status
RUO
Gene ID (Entrez)
110355, 156
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration
0.89 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
P25098, Q99MK8
Gene Symbols
GRK2
Quantity
25 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This affinity purified antibody is directed against human GRK2
- A BLAST analysis of the sequence shows 100% reactivity to human, and 90% to rat, mouse, and golden hamster
- G protein-coupled receptor kinases (GRKs) are important regulators of G protein-coupled receptors(GPCRs)
- GRK2 (83 kDa), one of six members of this family that have been identified, is ubiquitously expressed in mammals
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs (e.g., ?2-adrenergic receptor) are phosphorylated by GRKs
- Internalization of the GPCRs ,regulated by beta-arrestin-1, leads to activation of the Ras - Raf - ERK1&2 signaling pathway
- GRK2 activity is tightly controlled by different mechanisms including phosphorylation by kinases such as PKC, Src and ERK1&2, as well as interaction with various proteins
- ERK phosphorylates and thus inactivates GRK2 on serine 670 in a negative feedback mechanism.
Compare Similar Items
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Antigen: GRK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GRK2
Gene Alias: Adrbk1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; Beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; GRK2; GRK-2
Host Species: Goat
Regulatory Status: RUO
Gene ID (Entrez): 110355, 156
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration: 0.89 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P25098, Q99MK8
Gene Symbols: GRK2
Quantity: 25 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Antigen:
GRK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GRK2
Gene Alias:
Adrbk1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; Beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; GRK2; GRK-2
Host Species:
Goat
Regulatory Status:
RUO
Gene ID (Entrez):
110355, 156
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration:
0.89 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P25098, Q99MK8
Gene Symbols:
GRK2
Quantity:
25 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Antigen: Doublecortin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DCX
Gene Alias: BOS_25702; DBCN; Dbct; DC; Dcn; Dcx; doublecortex; doublecortin; Doublin; Lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS
Host Species: Goat
Regulatory Status: RUO
Gene ID (Entrez): 13193, 1641, 84394
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration: 0.79 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: O43602, O88809, Q9ESI7
Gene Symbols: DCX
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Antigen:
Doublecortin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DCX
Gene Alias:
BOS_25702; DBCN; Dbct; DC; Dcn; Dcx; doublecortex; doublecortin; Doublin; Lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS
Host Species:
Goat
Regulatory Status:
RUO
Gene ID (Entrez):
13193, 1641, 84394
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration:
0.79 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
O43602, O88809, Q9ESI7
Gene Symbols:
DCX
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Antigen: Doublecortin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DCX
Gene Alias: BOS_25702; DBCN; Dbct; DC; Dcn; Dcx; doublecortex; doublecortin; Doublin; Lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS
Host Species: Goat
Regulatory Status: RUO
Gene ID (Entrez): 13193, 1641, 84394
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration: 0.79 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: O43602, O88809, Q9ESI7
Gene Symbols: DCX
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Antigen:
Doublecortin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DCX
Gene Alias:
BOS_25702; DBCN; Dbct; DC; Dcn; Dcx; doublecortex; doublecortin; Doublin; Lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS
Host Species:
Goat
Regulatory Status:
RUO
Gene ID (Entrez):
13193, 1641, 84394
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration:
0.79 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
O43602, O88809, Q9ESI7
Gene Symbols:
DCX
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Antigen: Brn3b
Classification: Polyclonal
Conjugate: Unconjugated
Gene: POU4F2
Gene Alias: BOS_16291; Brain-3B; Brain-specific homeobox/POU domain protein 3B; brn3.2; Brn-3.2; BRN3B; brn-3b; Brn3b POU domain transcription factor; mBrn3-3R; POU class 4 homeobox 2; POU domain class 4 transcription factor 2; POU domain protein; POU domain transcription factor Brn3b-l; POU domain transcription factor Brn3b-s; POU domain, class 4, transcription factor 2; POU domain, class 4, transcription factor, related sequence 1; POU4F2; pou4f2/brn-3b; Pou4f-rs1
Host Species: Goat
Regulatory Status: RUO
Gene ID (Entrez): 171355, 18997
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration: 1.05 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: G3V7L5, Q63934
Gene Symbols: POU4F2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Antigen:
Brn3b
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
POU4F2
Gene Alias:
BOS_16291; Brain-3B; Brain-specific homeobox/POU domain protein 3B; brn3.2; Brn-3.2; BRN3B; brn-3b; Brn3b POU domain transcription factor; mBrn3-3R; POU class 4 homeobox 2; POU domain class 4 transcription factor 2; POU domain protein; POU domain transcription factor Brn3b-l; POU domain transcription factor Brn3b-s; POU domain, class 4, transcription factor 2; POU domain, class 4, transcription factor, related sequence 1; POU4F2; pou4f2/brn-3b; Pou4f-rs1
Host Species:
Goat
Regulatory Status:
RUO
Gene ID (Entrez):
171355, 18997
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Concentration:
1.05 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
G3V7L5, Q63934
Gene Symbols:
POU4F2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody