50-199-1889

Pdcd4Rabbit anti-Human, Mouse, Rat, Xenopus laevis, Polyclonal, Rockland™

Manufacturer: Rockland Immunochemicals

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Pack Size SKU Availability Price
Each of 1 50-199-1889-Each-of-1 In Stock ₹ 14,374.08

50-199-1889 - Each of 1

₹ 14,374.08

In Stock

Quantity

1

Base Price: ₹ 14,374.08

GST (18%): ₹ 2,587.334

Total Price: ₹ 16,961.414

Antigen

Pdcd4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PDCD4

Gene Alias

D19Ucla1; Death up-regulated gene protein; death-upregulated; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; PDCD4; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); Programmed cell death protein 4; Protein 197/15a; Protein MA-3; RP11-348N5.4; Tis; Topoisomerase-inhibitor suppressed protein

Host Species

Rabbit

Regulatory Status

RUO

Gene ID (Entrez)

18569, 27250, 64031

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q53EL6, Q61823, Q9JID1

Gene Symbols

PDCD4

Quantity

25 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat, X. laevis

Product Type

Antibody

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Directed against human Pdcd4 protein
  • A BLAST analysis was used to suggest cross-reactivity with Pdcd4 from human, mouse, rat and Xenopus based on 100% homology with the immunizing sequence
  • Cross-reactivity with Pdcd4 from other sources has not been determined
  • The antibody reacts with Pdcd4 protein that is either phosphorylated or non-phosphorylated at Ser457
  • Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation
  • During this process, the expression patterns of numerous genes are radically altered
  • One such gene is the programmed cell death protein 4 (PDCD4), whose expression was found to be upregulated in all cell lines following the onset of apoptosis
  • PDCD4 encodes a tumor suppressor protein whose expression is lost in carcinomas of breast, colon, lung and prostate
  • It can bind to and inhibit the helicase activity of the eukaryotic translation initiation factor 4A and inhibit the transactivation and transformation mediated by the transcription factor AP-1
  • The kinase Akt regulates PDCD4 by phosphorylation, decreasing the ability of PDCD4 to interfere with the transactivation of AP-1-responsive promoter by c-Jun
  • There are two known isoforms of PDCD4.

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Rockland Immunochemicals

50-199-1889

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Antigen:
Pdcd4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDCD4

Gene Alias:
D19Ucla1; Death up-regulated gene protein; death-upregulated; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; PDCD4; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); Programmed cell death protein 4; Protein 197/15a; Protein MA-3; RP11-348N5.4; Tis; Topoisomerase-inhibitor suppressed protein

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
18569, 27250, 64031

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q53EL6, Q61823, Q9JID1

Gene Symbols:
PDCD4

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, X. laevis

Product Type:
Antibody

Img

Bioworld

50-199-189

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Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Img

Rockland Immunochemicals

50-199-1890

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Antigen:
DAXX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAXX

Gene Alias:
BING2; BOS_21285; CENP-C binding protein; DADB-159G18.9; DAP6; DAXX; death domain associated protein; Death domain-associated protein 6; death-associated protein 6; death-domain associated protein; EAP1; ETS1-associated protein 1; Fas death domain-associated protein; Fas-binding protein; hDaxx; MGC126245; MGC126246

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
13163, 140926, 1616

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Western Blot

Concentration:
1.06 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O35613, Q8VIB2, Q9UER7

Gene Symbols:
DAXX

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Img

Fischer Scientific

50-199-1891

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Antigen:
ABCB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABCB1

Gene Alias:
ABC20; ABCB1; Abcb1a; Abcb1b; Abcb4; ATP binding cassette subfamily B member 1; ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette sub-family B member 1; ATP-binding cassette sub-family B member 1A; ATP-binding cassette sub-family B member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette, subfamily B (MDR/TAP), member 1A; ATP-binding cassette, sub-family B (MDR/TAP), member 1A; ATP-binding cassette, subfamily B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 1B; ATP-binding cassette, sub-family B (MDR/TAP), member 4; ATP-binding cassette, subfamily B, member 1A; ATP-binding cassette, subfamily B, member 1B; ATP-dependent translocase ABCB1; BOS_4142; CD243; CLCS; colchicin sensitivity; doxorubicin resistance; ecotropic viral integration site 32; Evi32; GP170; mdr; MDR1; M

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
170913, 18669, 18671, 24646, 403879, 5243

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P06795, P08183, P21447

Gene Symbols:
ABCB1, Abcb1a, Abcb1b

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Monkey, Mouse, Rat

Product Type:
Antibody