50-199-1930
SMAD4Rabbit anti-Human, Mouse, Xenopus laevis, Polyclonal, Rockland™
Manufacturer: Rockland Immunochemicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-1930-Each-of-1 | In Stock | ₹ 50,884.24 |
50-199-1930 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,884.24
GST (18%): ₹ 9,159.163
Total Price: ₹ 60,043.403
Antigen
SMAD4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMAD4
Gene Alias
AW743858; D18Wsu70e; deleted in pancreatic carcinoma locus 4; Deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; Dpc4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MADH4; Mothers against decapentaplegic homolog 4; mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; Smad4
Host Species
Rabbit
Regulatory Status
RUO
Gene ID (Entrez)
17128, 4089
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Western Blot
Concentration
1.2 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
P97471, Q13485
Gene Symbols
SMAD4
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, X. laevis
Product Type
Antibody
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Directed against human SMAD4 protein
- A BLAST analysis was used to suggest cross-reactivity with SMAD4 protein from human, mouse and Xenopus based on 100% homology with the immunizing sequence
- Reactivity against homologues from other sources is not known
- Smad4 is encoded by the Smad4 gene that is located on chromosome 18 in humans
- Smad4 is also known as Smad family member 4, Sma- and Mad-related protein 4 or Mothers against decapentaplegic (MAD) homolog 4
- Smad4 contains N-terminal MH1 (MAD homology 1) and C-terminal MH2 (MAD homology 2) globular domains that are involved in DNA binding and protein interactions respectively
- Binding of the TGF-beta superfamily of ligands that includes Transforming Growth Factor -beta (TGF-beta) and bone morphogenetic protein (BMP) to its cognate receptor allows phosphorylation of Smad 1, 2, 3, 5 and 8 (R-Smad, Receptor Smad)
- This signals for heterotrimerization with Smad4 (co-Smad, co-mediator Smad) and translocation of the complex to the nucleus
- Inhibitory or antagonistic Smad (I-Smad) that includes Smad 6 and 7, interact with activated R-Smads and attenuate the signaling pathway
- Smad4 acts as a tumor suppressor protein by transcriptionally regulating its target genes such as Cyclin D1 (downregulation) and collagen (upregulation) that inhibit cell proliferation
- Dephosphorylation regulates nuclear export and nucleocytoplasmic dynamics of Smads.
Compare Similar Items
Show Difference
Antigen: SMAD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD4
Gene Alias: AW743858; D18Wsu70e; deleted in pancreatic carcinoma locus 4; Deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; Dpc4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MADH4; Mothers against decapentaplegic homolog 4; mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; Smad4
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 17128, 4089
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 1.2 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P97471, Q13485
Gene Symbols: SMAD4
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, X. laevis
Product Type: Antibody
Antigen:
SMAD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD4
Gene Alias:
AW743858; D18Wsu70e; deleted in pancreatic carcinoma locus 4; Deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; Dpc4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MADH4; Mothers against decapentaplegic homolog 4; mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; Smad4
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
17128, 4089
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
1.2 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P97471, Q13485
Gene Symbols:
SMAD4
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, X. laevis
Product Type:
Antibody
Antigen: Phospho-Stat5 (Tyr694)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT5A
Gene Alias: AA959963; BOS_19069; Mammary gland factor; mammary gland factor STAT5A; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5A; STAT; STAT5; Stat5a; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 20850, 24918, 6776
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P42229, P42230, Q62771
Gene Symbols: STAT5A
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Antigen:
Phospho-Stat5 (Tyr694)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT5A
Gene Alias:
AA959963; BOS_19069; Mammary gland factor; mammary gland factor STAT5A; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5A; STAT; STAT5; Stat5a; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
20850, 24918, 6776
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P42229, P42230, Q62771
Gene Symbols:
STAT5A
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Antigen: Cenexin-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ODF2
Gene Alias: 84 kDa outer dense fiber protein; AI848335; cancer/testis antigen 134; Cenexin; cenexin 1; CT134; KKT4; MMTEST29; ODF2; ODF2/1; ODF2/2; Odf84; outer dense fiber of sperm tail 2; outer dense fiber of sperm tails 2; Outer dense fiber of sperm tails protein 2; outer dense fiber of sperm tails, 84-kD; Outer dense fiber protein 2; RP11-187B3.1; sperm outer dense fiber major protein 2; sperm tail structural protein; testis tissue sperm-binding protein Li 51e; testis-specific autoantigen
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 464769, 4957, 717505
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: Q5BJF6
Gene Symbols: ODF2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Chimpanzee, Human, Rhesus Monkey
Product Type: Antibody
Antigen:
Cenexin-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ODF2
Gene Alias:
84 kDa outer dense fiber protein; AI848335; cancer/testis antigen 134; Cenexin; cenexin 1; CT134; KKT4; MMTEST29; ODF2; ODF2/1; ODF2/2; Odf84; outer dense fiber of sperm tail 2; outer dense fiber of sperm tails 2; Outer dense fiber of sperm tails protein 2; outer dense fiber of sperm tails, 84-kD; Outer dense fiber protein 2; RP11-187B3.1; sperm outer dense fiber major protein 2; sperm tail structural protein; testis tissue sperm-binding protein Li 51e; testis-specific autoantigen
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
464769, 4957, 717505
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
Q5BJF6
Gene Symbols:
ODF2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Chimpanzee, Human, Rhesus Monkey
Product Type:
Antibody
Antigen: Phospho-Cenexin-1 (Ser796)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ODF2
Gene Alias: 84 kDa outer dense fiber protein; AI848335; cancer/testis antigen 134; Cenexin; cenexin 1; CT134; KKT4; MMTEST29; ODF2; ODF2/1; ODF2/2; Odf84; outer dense fiber of sperm tail 2; outer dense fiber of sperm tails 2; Outer dense fiber of sperm tails protein 2; outer dense fiber of sperm tails, 84-kD; Outer dense fiber protein 2; RP11-187B3.1; sperm outer dense fiber major protein 2; sperm tail structural protein; testis tissue sperm-binding protein Li 51e; testis-specific autoantigen
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 464769, 4957, 717505
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: Q5BJF6
Gene Symbols: ODF2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Chimpanzee, Human, Rhesus Monkey
Product Type: Antibody
Antigen:
Phospho-Cenexin-1 (Ser796)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ODF2
Gene Alias:
84 kDa outer dense fiber protein; AI848335; cancer/testis antigen 134; Cenexin; cenexin 1; CT134; KKT4; MMTEST29; ODF2; ODF2/1; ODF2/2; Odf84; outer dense fiber of sperm tail 2; outer dense fiber of sperm tails 2; Outer dense fiber of sperm tails protein 2; outer dense fiber of sperm tails, 84-kD; Outer dense fiber protein 2; RP11-187B3.1; sperm outer dense fiber major protein 2; sperm tail structural protein; testis tissue sperm-binding protein Li 51e; testis-specific autoantigen
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
464769, 4957, 717505
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
Q5BJF6
Gene Symbols:
ODF2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Chimpanzee, Human, Rhesus Monkey
Product Type:
Antibody