50-199-1968
NEDD4 Polyclonal Antibody, Rockland™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-1968-Each-of-1 | In Stock | ₹ 50,884.24 |
50-199-1968 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,884.24
GST (18%): ₹ 9,159.163
Total Price: ₹ 60,043.403
Antigen
NEDD4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NEDD4
Gene Alias
AA959633; AL023035; AU019897; Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; Nedd4; Nedd-4; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1
Host Species
Rabbit
Regulatory Status
RUO
Gene ID (Entrez)
100054735, 4734, 699550
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Concentration
0.64 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
P46934
Gene Symbols
NEDD4
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Equine, Human, Rhesus Monkey
Product Type
Antibody
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody reacts with endogenous Nedd4 protein
- A BLAST analysis was used to suggest reactivity with Nedd4 from human, horse and macaque based on a 100% homology with the immunizing sequence
- Expect reactivity with Nedd4 from chimpanzee, rabbit, dog, and cattle based on a 94% homology with the immunizing sequence
- Cross-reactivity with Nedd4 from other sources has not been determined
- The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein
- It contains one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains
- It is involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity
- It acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53
- It is also reported to be involved in the budding of many viruses and is the regulator of epithelial Na+ channels, which lead to arterial hypertension
- NEDD4 protein is localized to the sarcolemmal region of muscle fibers
- Increase in NEDD4 protein expression leads to unloaded and denervated muscles as well as a decrease in Notch1 expression
- Hence it acts as down regulator of Notch-1 gene expression.
Compare Similar Items
Show Difference
Antigen: NEDD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NEDD4
Gene Alias: AA959633; AL023035; AU019897; Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; Nedd4; Nedd-4; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 100054735, 4734, 699550
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Concentration: 0.64 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P46934
Gene Symbols: NEDD4
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Equine, Human, Rhesus Monkey
Product Type: Antibody
Antigen:
NEDD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEDD4
Gene Alias:
AA959633; AL023035; AU019897; Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; Nedd4; Nedd-4; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
100054735, 4734, 699550
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Concentration:
0.64 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P46934
Gene Symbols:
NEDD4
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Equine, Human, Rhesus Monkey
Product Type:
Antibody
Antigen: NEDD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NEDD4
Gene Alias: AA959633; AL023035; AU019897; Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; Nedd4; Nedd-4; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 100054735, 4734, 699550
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Concentration: 0.64 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P46934
Gene Symbols: NEDD4
Quantity: 25 μL
Primary or Secondary: Primary
Target Species: Equine, Human, Rhesus Monkey
Product Type: Antibody
Antigen:
NEDD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEDD4
Gene Alias:
AA959633; AL023035; AU019897; Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; Nedd4; Nedd-4; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
100054735, 4734, 699550
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Concentration:
0.64 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P46934
Gene Symbols:
NEDD4
Quantity:
25 μL
Primary or Secondary:
Primary
Target Species:
Equine, Human, Rhesus Monkey
Product Type:
Antibody
Antigen: c-Myb
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYB
Gene Alias: AI550390; Cmyb; c-myb; cmyb protein; c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; efg; gag-myb protein; M16449; Myb; myb proto-oncogene protein; MYB proto-oncogene, transcription factor; myeloblastosis oncogene; myeloblastosis proto-oncogene product; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; transcription factor cmyb; Transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 17863
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 1.51 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P06876
Gene Symbols: MYB
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Antigen:
c-Myb
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYB
Gene Alias:
AI550390; Cmyb; c-myb; cmyb protein; c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; efg; gag-myb protein; M16449; Myb; myb proto-oncogene protein; MYB proto-oncogene, transcription factor; myeloblastosis oncogene; myeloblastosis proto-oncogene product; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; transcription factor cmyb; Transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
17863
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
1.51 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P06876
Gene Symbols:
MYB
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Antigen: c-Myb
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYB
Gene Alias: AI550390; Cmyb; c-myb; cmyb protein; c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; efg; gag-myb protein; M16449; Myb; myb proto-oncogene protein; MYB proto-oncogene, transcription factor; myeloblastosis oncogene; myeloblastosis proto-oncogene product; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; transcription factor cmyb; Transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 17863
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 1.51 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P06876
Gene Symbols: MYB
Quantity: 25 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Antigen:
c-Myb
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYB
Gene Alias:
AI550390; Cmyb; c-myb; cmyb protein; c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; efg; gag-myb protein; M16449; Myb; myb proto-oncogene protein; MYB proto-oncogene, transcription factor; myeloblastosis oncogene; myeloblastosis proto-oncogene product; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; transcription factor cmyb; Transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
17863
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
1.51 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P06876
Gene Symbols:
MYB
Quantity:
25 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody