50-199-2134

Methyl-Retinoblastoma (Lys860) Polyclonal Antibody, Rockland™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-2134-Each-of-1 In Stock ₹ 14,374.08

50-199-2134 - Each of 1

₹ 14,374.08

In Stock

Quantity

1

Base Price: ₹ 14,374.08

GST (18%): ₹ 2,587.334

Total Price: ₹ 16,961.414

Antigen

Methyl-Retinoblastoma K860 Me1 (Lys860)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RB1

Gene Alias

Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; Rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; Retinoblastoma 1 (including osteosarcoma); retinoblastoma protein; retinoblastoma suspectibility protein; Retinoblastoma-associated protein

Host Species

Rabbit

Regulatory Status

RUO

Gene ID (Entrez)

5925

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Dot Blot, ELISA, Immunoprecipitation, Western Blot

Concentration

0.99 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

P06400

Gene Symbols

RB1

Quantity

25 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This affinity purified antibody is directed against human Retinoblastoma
  • This antibody reacts with human RB1 surrounding aa860 and is specific for K860 Me1
  • Blast analysis of the sequence of the immunogen shows 100% identity with human and 92% identity to rat and mouse
  • Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA
  • It is phosphorylated on serine and threonine, but not on tyrosine residues
  • It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E
  • Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth
  • Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-2134

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Antigen:
Methyl-Retinoblastoma K860 Me1 (Lys860)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RB1

Gene Alias:
Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; Rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; Retinoblastoma 1 (including osteosarcoma); retinoblastoma protein; retinoblastoma suspectibility protein; Retinoblastoma-associated protein

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
5925

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunoprecipitation, Western Blot

Concentration:
0.99 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P06400

Gene Symbols:
RB1

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Fischer Scientific

50-199-2135

--


Antigen:
PIAS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIAS1

Gene Alias:
2900068C24Rik; AR interacting protein; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; E3 SUMO-protein transferase PIAS1; GBP; Gu binding protein; GU/RH-II; Gu-binding protein; PIAS1; protein inhibitor of activated STAT 1; Protein inhibitor of activated STAT protein 1; protein inhibitor of activated STAT, 1; protein inhibitor of activated STAT-1; RING-type E3 ubiquitin transferase PIAS1; RNA helicase II-binding protein; zinc finger, MIZ-type containing 3; ZMIZ3

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
8554

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.01M sodium phosphate with 0.25M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O75925

Gene Symbols:
PIAS1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Fischer Scientific

50-199-2136

--


Antigen:
PIAS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIAS1

Gene Alias:
2900068C24Rik; AR interacting protein; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; E3 SUMO-protein transferase PIAS1; GBP; Gu binding protein; GU/RH-II; Gu-binding protein; PIAS1; protein inhibitor of activated STAT 1; Protein inhibitor of activated STAT protein 1; protein inhibitor of activated STAT, 1; protein inhibitor of activated STAT-1; RING-type E3 ubiquitin transferase PIAS1; RNA helicase II-binding protein; zinc finger, MIZ-type containing 3; ZMIZ3

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
8554

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.01M sodium phosphate with 0.25M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O75925

Gene Symbols:
PIAS1

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Img

Fischer Scientific

50-199-2139

--


Antigen:
H2AX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2AX

Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2a.x; H2a/x; h2afx; H2AX; H2AX histone; Hist5-2ax; histone 5 protein 2ax; Histone H2A.X; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329

Host Species:
Rabbit

Regulatory Status:
RUO

Gene ID (Entrez):
3014

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P16104

Gene Symbols:
H2AX

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody