50-199-2293
Phospho-SMAD2 (Ser465, Ser467) Polyclonal Antibody, Rockland™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-2293-Each-of-1 | In Stock | ₹ 50,884.24 |
50-199-2293 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,884.24
GST (18%): ₹ 9,159.163
Total Price: ₹ 60,043.403
Antigen
Phospho-SMAD2 (Ser465, Ser467)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMAD2
Gene Alias
7120426M23Rik; BOS_22266; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; SMAD2; Smad-2; Smad2Deltaexon3
Host Species
Rabbit
Regulatory Status
RUO
Gene ID (Entrez)
4087
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Western Blot
Concentration
0.94 mg/mL
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.
Q15796
Gene Symbols
SMAD2
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Anti-SMAD2 pS465 pS467 antibody is directed against the phosphorylated form of human Smad2 protein at the pS465 and pS467 residues
- Reactivity occurs against human SMAD2
- Reactivity with non-phosphorylated human Smad2 is minimal by ELISA and western blot
- A BLAST analysis was used to suggest cross-reactivity with Smad2 protein from human, mouse, rat, orangutan, and bovine based on 100% homology with the immunizing sequence
- Reactivity against homologues from other sources is not known
- SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
- SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
- Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
- In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
- The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
- The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
- SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
- Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.
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Antigen: Phospho-SMAD2 (Ser465, Ser467)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD2
Gene Alias: 7120426M23Rik; BOS_22266; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; SMAD2; Smad-2; Smad2Deltaexon3
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 4087
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 0.94 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: Q15796
Gene Symbols: SMAD2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Antigen:
Phospho-SMAD2 (Ser465, Ser467)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD2
Gene Alias:
7120426M23Rik; BOS_22266; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; SMAD2; Smad-2; Smad2Deltaexon3
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
4087
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
0.94 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
Q15796
Gene Symbols:
SMAD2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Antigen: Phospho-SMAD2 (Ser465, Ser467)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD2
Gene Alias: 7120426M23Rik; BOS_22266; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; SMAD2; Smad-2; Smad2Deltaexon3
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 4087
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 0.94 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: Q15796
Gene Symbols: SMAD2
Quantity: 25 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Antigen:
Phospho-SMAD2 (Ser465, Ser467)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD2
Gene Alias:
7120426M23Rik; BOS_22266; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; SMAD2; Smad-2; Smad2Deltaexon3
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
4087
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
0.94 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
Q15796
Gene Symbols:
SMAD2
Quantity:
25 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Antigen: Methyl-Histone H3 (Lys27)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H3-3A
Gene Alias: H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3 K9; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3C10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3B; h3f3b.1; H3F3C; h3f3d; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K9; H3Lys9me3; Hist1; HIST1H3A; Hist1h3b; Hist1h3c; Hist1h3d; HIST1H3E; HIST1H3F; HIST1H3G; Hist1h3h; Hist1h3i; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone gene complex 1; histone H3; Histone H3.1; Histone H3.2; Histone H3.3; Histone H3.3C; Histone H3.5; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; Histone H3/m; Histone H3/o; Histone H3K9me3; histone variant H3.5; hypothetical protein LOC550262; M32461; methyl Histone 3; methyl Histone H3; PP781; Trimethyl H3; Tri-methyl H3; Trimethyl Histone H3; Tri-methyl Histone H3; Tri-Methyl-H3 K9; Tri-Methyl-H3 Lys9; Tri-Methyl-Histone H3 K9; Tri-Methyl-Histone H3 Lys9; wu:fa25h06; wu:fa96g06; wu:fb07a08; wu:fb36f01; zgc:110292; zgc:174300; zgc:56193; zgc:56418; zgc:64222; zgc:86731
Host Species: Rabbit
Regulatory Status: RUO
Gene ID (Entrez): 117056, 126961, 180073, 260423, 3020, 3021, 319150, 319152, 333932, 360198, 440093, 625328, 8350, 8357, 8358, 8968, 97114
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Dot Blot, Immunoprecipitation, Western Blot
Concentration: 0.83 mg/mL
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.: P02301, P09588, P68431, P68433, P84228, P84243, P84245, Q6NXT2, Q71DI3
Gene Symbols: H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7, his-3
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: C. elegans, Human, Mouse, Rat
Product Type: Antibody
Antigen:
Methyl-Histone H3 (Lys27)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H3-3A
Gene Alias:
H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3 K9; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3C10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3B; h3f3b.1; H3F3C; h3f3d; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K9; H3Lys9me3; Hist1; HIST1H3A; Hist1h3b; Hist1h3c; Hist1h3d; HIST1H3E; HIST1H3F; HIST1H3G; Hist1h3h; Hist1h3i; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone gene complex 1; histone H3; Histone H3.1; Histone H3.2; Histone H3.3; Histone H3.3C; Histone H3.5; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; Histone H3/m; Histone H3/o; Histone H3K9me3; histone variant H3.5; hypothetical protein LOC550262; M32461; methyl Histone 3; methyl Histone H3; PP781; Trimethyl H3; Tri-methyl H3; Trimethyl Histone H3; Tri-methyl Histone H3; Tri-Methyl-H3 K9; Tri-Methyl-H3 Lys9; Tri-Methyl-Histone H3 K9; Tri-Methyl-Histone H3 Lys9; wu:fa25h06; wu:fa96g06; wu:fb07a08; wu:fb36f01; zgc:110292; zgc:174300; zgc:56193; zgc:56418; zgc:64222; zgc:86731
Host Species:
Rabbit
Regulatory Status:
RUO
Gene ID (Entrez):
117056, 126961, 180073, 260423, 3020, 3021, 319150, 319152, 333932, 360198, 440093, 625328, 8350, 8357, 8358, 8968, 97114
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Dot Blot, Immunoprecipitation, Western Blot
Concentration:
0.83 mg/mL
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Accession No.:
P02301, P09588, P68431, P68433, P84228, P84243, P84245, Q6NXT2, Q71DI3
Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7, his-3
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
C. elegans, Human, Mouse, Rat
Product Type:
Antibody
Antigen: __
Classification: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Quantity: __
Primary or Secondary: __
Target Species: __
Product Type: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
__
Applications:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Quantity:
__
Primary or Secondary:
__
Target Species:
__
Product Type:
__