50-199-2687

SIRT1 Monoclonal Antibody (2G1/F7), Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-2687-Each-of-1 In Stock ₹ 12,834.00

50-199-2687 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

SIRT1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

10mM sodium phosphate with 150mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.

Q96EB6

Gene Symbols

SIRT1

Immunogen

This SIRT1 antibody was raised against a synthetic peptide corresponding to amino acids 581-630 of human SIRT1.

Quantity

10 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

2G1/F7

Conjugate

Unconjugated

Gene

SIRT1

Gene Alias

75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; Sir2; Sir2a; SIR2alpha; Sir2l1; sir2-like 1; SIR2-like protein 1; SIRT1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

23411

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • NAD-dependent protein deacetylase sirtuin-1 (SIRT1) links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, repsonse to DNA damage, metabolism, apoptosis, and autophagy
  • SIRT1 can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histone and DNA, leading to transcriptional repression
  • It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-2687

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Antigen:
SIRT1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
10mM sodium phosphate with 150mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q96EB6

Gene Symbols:
SIRT1

Immunogen:
This SIRT1 antibody was raised against a synthetic peptide corresponding to amino acids 581-630 of human SIRT1.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
2G1/F7

Conjugate:
Unconjugated

Gene:
SIRT1

Gene Alias:
75SirT1; AA673258; hSIR2; hSIRT1; mSIR2a; NAD-dependent deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; OTTHUMP00000198111; OTTHUMP00000198112; Regulatory protein SIR2 homolog 1; RP11-57G10.3; Sir2; Sir2a; SIR2alpha; Sir2l1; sir2-like 1; SIR2-like protein 1; SIRT1; SirtT1 75 kDa fragment; sirtuin 1; sirtuin 1 ((silent mating type information regulation 2, homolog) 1; sirtuin type 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
23411

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-2688

--


Antigen:
Ikaros

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
Q03267

Gene Symbols:
IKZF1

Immunogen:
This Ikaros antibody was raised against a recombinant protein corresponding to the N-terminal half of mouse Ikaros.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Clone:
2A9

Conjugate:
Unconjugated

Gene:
IKZF1

Gene Alias:
5832432G11Rik; BOS_3969; CLL-associated antigen KW-6; CVID13; DNA-binding protein Ikaros; hIk-1; hlk-1; Hs.54452; IK1; IKAROS; IKAROS family zinc finger 1; IKAROS family zinc finger 1 (Ikaros); Ikaros family zinc finger protein 1; IKZF1; KAROS family zinc finger 1 (Ikaros); LYF1; LyF-1; Lymphoid transcription factor LyF-1; mKIAA4227; PPP1R92; PRO0758; protein phosphatase 1, regulatory subunit 92; RGD1562979; Zfpn1a1; zinc finger containing transcription factor; zinc finger protein, subfamily 1A, 1 (Ikaros); ZNFN1A1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
22778

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-2689

--


Antigen:
Ikaros

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
Q03267

Gene Symbols:
IKZF1

Immunogen:
This Ikaros antibody was raised against a recombinant protein corresponding to the N-terminal half of mouse Ikaros.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Clone:
2A9

Conjugate:
Unconjugated

Gene:
IKZF1

Gene Alias:
5832432G11Rik; BOS_3969; CLL-associated antigen KW-6; CVID13; DNA-binding protein Ikaros; hIk-1; hlk-1; Hs.54452; IK1; IKAROS; IKAROS family zinc finger 1; IKAROS family zinc finger 1 (Ikaros); Ikaros family zinc finger protein 1; IKZF1; KAROS family zinc finger 1 (Ikaros); LYF1; LyF-1; Lymphoid transcription factor LyF-1; mKIAA4227; PPP1R92; PRO0758; protein phosphatase 1, regulatory subunit 92; RGD1562979; Zfpn1a1; zinc finger containing transcription factor; zinc finger protein, subfamily 1A, 1 (Ikaros); ZNFN1A1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
22778

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Bioworld

50-199-269

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