50-199-2718

HIRA Monoclonal Antibody (WC15), Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-2718-Each-of-1 In Stock ₹ 12,834.00

50-199-2718 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

HIRA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.

P54198, Q61666

Gene Symbols

HIRA

Immunogen

This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.

Quantity

10 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunoprecipitation, Western Blot

Clone

WC15

Conjugate

Unconjugated

Gene

HIRA

Gene Alias

AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

15260, 7290

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes
  • Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochromatin
  • It plays an important role in the formation of the senescence-associated heterochromatin foci
  • These foci likely mediate the irreversible cell cycle changes that occur in senescent cells
  • It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.

Compare Similar Items

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Img

Fischer Scientific

50-199-2718

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Antigen:
HIRA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P54198, Q61666

Gene Symbols:
HIRA

Immunogen:
This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
WC15

Conjugate:
Unconjugated

Gene:
HIRA

Gene Alias:
AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
15260, 7290

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-2721

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Antigen:
Phospho-RNA pol II CTD (Ser2)

Classification:
Polyclonal

Concentration:
Lot-Specific

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P09884, P24928

Gene Symbols:
POLA1, POLR2A

Immunogen:
This RNA pol II CTD phospho Ser2 antibody was raised against a peptide containing the RNA Pol II CTD sequence phosphorylated at serine 2.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot, Immunoprecipitation, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
POLR2A

Gene Alias:
220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; polymerase, alpha 1; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II largest subunit; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; RPB1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5422, 5430

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-2722

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Antigen:
Phospho-RNA pol II CTD (Ser2)

Classification:
Polyclonal

Concentration:
Lot-Specific

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P09884, P24928

Gene Symbols:
POLA1, POLR2A

Immunogen:
This RNA pol II CTD phospho Ser2 antibody was raised against a peptide containing the RNA Pol II CTD sequence phosphorylated at serine 2.

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot, Immunoprecipitation, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
POLR2A

Gene Alias:
220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; polymerase, alpha 1; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II largest subunit; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; RPB1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5422, 5430

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-2723

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Antigen:
Histone H3K79ac

Classification:
Polyclonal

Concentration:
Lot-Specific

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Immunogen:
This Histone H3 acetyl Lys79 antibody was raised against a peptide containing acetyl-lysine 79 of human histone H3.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Dot Blot, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
H3-3A

Gene Alias:
Acetyl H3; Acetyl Histone H3; Acetyl-H3 K79; Acetyl-H3 Lys79; Acetyl-Histone H3 K79; Acetyl-Histone H3 Lys79; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K79ac; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3c10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3f3b; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K79; H3Lys79ac; Hist1; HIST1H3A; Hist1h3b; Hist1h3c; HIST1H3D; HIST1H3E; Hist1h3f; Hist1h3g; Hist1h3h; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1;

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid