50-199-2836
Estrogen Receptor beta Monoclonal Antibody (CO1531), Active Motif™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-2836-Each-of-1 | In Stock | ₹ 50,480.40 |
50-199-2836 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,480.40
GST (18%): ₹ 9,086.472
Total Price: ₹ 59,566.872
Antigen
Estrogen Receptor beta
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.
Q92731
Gene Symbols
ESR2
Immunogen
This Estrogen Receptor beta antibody was raised against a recombinant protein corresponding to amino acids 212-477 of human Estrogen Receptor beta.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
CO1531
Conjugate
Unconjugated
Gene
ESR2
Gene Alias
ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; ESR2; ESRB; ESR-BETA; Estrb; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; Estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; Nr3a2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
2100
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described
- Human ER beta was initially cloned and characterized from testis
- Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
- The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
- When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
- There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
- Estrogen receptor beta (ER beta) binds estrogens with an affinity similar to that of estrogen receptor alpha
- Some ER beta isoforms dominantly inhibit the activity of estrogen receptor alpha in reproductive tissues
- ER beta is found widely in many tissues throughout the body and can act as a potent tumor suppressor, playing a crucial role in many cancer types such as prostate cancer, autism spectrum disorder, medullary thyroid carcinoma, De Quervain Disease and risk of cardiovascular disease.
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Antigen: Estrogen Receptor beta
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: Q92731
Gene Symbols: ESR2
Immunogen: This Estrogen Receptor beta antibody was raised against a recombinant protein corresponding to amino acids 212-477 of human Estrogen Receptor beta.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: CO1531
Conjugate: Unconjugated
Gene: ESR2
Gene Alias: ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; ESR2; ESRB; ESR-BETA; Estrb; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; Estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; Nr3a2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 2100
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Estrogen Receptor beta
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
Q92731
Gene Symbols:
ESR2
Immunogen:
This Estrogen Receptor beta antibody was raised against a recombinant protein corresponding to amino acids 212-477 of human Estrogen Receptor beta.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
CO1531
Conjugate:
Unconjugated
Gene:
ESR2
Gene Alias:
ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; ESR2; ESRB; ESR-BETA; Estrb; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; Estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; Nr3a2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
2100
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Estrogen Receptor beta
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: Q92731
Gene Symbols: ESR2
Immunogen: This Estrogen Receptor beta antibody was raised against a recombinant protein corresponding to amino acids 212-477 of human Estrogen Receptor beta.
Quantity: 10 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: CO1531
Conjugate: Unconjugated
Gene: ESR2
Gene Alias: ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; ESR2; ESRB; ESR-BETA; Estrb; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; Estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; Nr3a2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 2100
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Estrogen Receptor beta
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
Q92731
Gene Symbols:
ESR2
Immunogen:
This Estrogen Receptor beta antibody was raised against a recombinant protein corresponding to amino acids 212-477 of human Estrogen Receptor beta.
Quantity:
10 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
CO1531
Conjugate:
Unconjugated
Gene:
ESR2
Gene Alias:
ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; ESR2; ESRB; ESR-BETA; Estrb; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; Estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; Nr3a2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
2100
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Immunogen: __
Quantity: __
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Primary or Secondary:
__
Target Species:
__
Product Type:
__
Isotype:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
__
Antigen: EuHMT1
Classification: Polyclonal
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: Q9H9B1
Gene Symbols: EHMT1
Immunogen: This EuHMT1 antibody was raised against a peptide derived from the N-terminal region of human EuHMT1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: __
Conjugate: Unconjugated
Gene: EHMT1
Gene Alias: bA188C12.1; EHMT1; euchromatic histone lysine methyltransferase 1; Euchromatic histone-lysine N-methyltransferase 1; EUHMTASE1; Eu-HMTase1; FP13812; G9a-like protein 1; GLP; GLP1; H3-K9-HMTase 5; Histone H3-K9 methyltransferase 5; Histone-lysine N-methyltransferase EHMT1; histone-lysine N-methyltransferase, H3 lysine-9 specific 5; KIAA1876; KMT1D; Lysine N-methyltransferase 1D
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 79813
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
EuHMT1
Classification:
Polyclonal
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
Q9H9B1
Gene Symbols:
EHMT1
Immunogen:
This EuHMT1 antibody was raised against a peptide derived from the N-terminal region of human EuHMT1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
EHMT1
Gene Alias:
bA188C12.1; EHMT1; euchromatic histone lysine methyltransferase 1; Euchromatic histone-lysine N-methyltransferase 1; EUHMTASE1; Eu-HMTase1; FP13812; G9a-like protein 1; GLP; GLP1; H3-K9-HMTase 5; Histone H3-K9 methyltransferase 5; Histone-lysine N-methyltransferase EHMT1; histone-lysine N-methyltransferase, H3 lysine-9 specific 5; KIAA1876; KMT1D; Lysine N-methyltransferase 1D
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
79813
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid