50-199-2981
SREBP-1 Monoclonal Antibody (IgG-2A4), Active Motif™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-2981-Each-of-1 | In Stock | ₹ 50,480.40 |
50-199-2981 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,480.40
GST (18%): ₹ 9,086.472
Total Price: ₹ 59,566.872
Antigen
SREBP-1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.
P36956
Gene Symbols
SREBF1
Immunogen
This SREBP-1 antibody was raised against a recombinant protein corresponding to amino acids 301-407 of human SREBP-1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ChIP Assay, Gel Shift, Immunoprecipitation, Western Blot
Clone
IgG-2A4
Conjugate
Unconjugated
Gene
SREBF1
Gene Alias
ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; BHLHD1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; Sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
6720
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Sterol regulatory element-binding proteins (SREBPs) are transcription factors that are members of the basic helix-loop-helix leucine zipper family of DNA binding proteins
- Three isoforms have been identified in mammalian tissues that vary in structure, regulation, and function
- SREBP-1a and SREBP-1c (originally cloned as ADD1) are protein products of alternative promoter usage of the SREBP-1 gene
- The third isoform is transcribed from a different gene, SREBP-2
- SREBPs are present as 120 kDa inactive precursors in the endoplasmic reticulum (ER) membrane
- Upon activation, the SREBP protein is translocated to the Golgi and proteolytic cleavage occurs resulting in a mature transcriptionally active 60-78 kDa fragment
- In liver and adipose tissues, SREBPs have a significant influence on lipid and cholesterol accumulation by inducing the transcription of genes involved in these processes
- While SREBP-1 is thought to be more important in regulating the expression of genes involved in triglyceride synthesis and accumulation, SREBP-2 has been more closely linked to those involved in cholesterol synthesis and accumulation.
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Antigen: SREBP-1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: P36956
Gene Symbols: SREBF1
Immunogen: This SREBP-1 antibody was raised against a recombinant protein corresponding to amino acids 301-407 of human SREBP-1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Gel Shift, Immunoprecipitation, Western Blot
Clone: IgG-2A4
Conjugate: Unconjugated
Gene: SREBF1
Gene Alias: ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; BHLHD1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; Sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6720
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SREBP-1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
P36956
Gene Symbols:
SREBF1
Immunogen:
This SREBP-1 antibody was raised against a recombinant protein corresponding to amino acids 301-407 of human SREBP-1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Gel Shift, Immunoprecipitation, Western Blot
Clone:
IgG-2A4
Conjugate:
Unconjugated
Gene:
SREBF1
Gene Alias:
ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; BHLHD1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; Sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6720
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SREBP-1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: P36956
Gene Symbols: SREBF1
Immunogen: This SREBP-1 antibody was raised against a recombinant protein corresponding to amino acids 301-407 of human SREBP-1.
Quantity: 10 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Gel Shift, Immunoprecipitation, Western Blot
Clone: IgG-2A4
Conjugate: Unconjugated
Gene: SREBF1
Gene Alias: ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; BHLHD1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; Sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6720
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SREBP-1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
P36956
Gene Symbols:
SREBF1
Immunogen:
This SREBP-1 antibody was raised against a recombinant protein corresponding to amino acids 301-407 of human SREBP-1.
Quantity:
10 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Gel Shift, Immunoprecipitation, Western Blot
Clone:
IgG-2A4
Conjugate:
Unconjugated
Gene:
SREBF1
Gene Alias:
ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; BHLHD1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; Sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6720
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SREBP-2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: Q12772
Gene Symbols: SREBF2
Immunogen: This SREBP-2 antibody was raised against a recombinant protein corresponding to amino acids 833-1141 of human SREBP-2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: IgG-1C6
Conjugate: Unconjugated
Gene: SREBF2
Gene Alias: AI608257; BHLHD2; Class D basic helix-loop-helix protein 2; EMBL:AAI01903.1}; lop13; nuc; Processed sterol regulatory element-binding protein 2; srebf2; srebf2 {ECO:0000312; Srebf2_retired; SREBP2; SREBP-2; SREBP2gc; sterol regulatory element binding factor 2; sterol regulatory element binding protein 2; sterol regulatory element binding transcription factor 2; Sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2; zgc:158371
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6721
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SREBP-2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
Q12772
Gene Symbols:
SREBF2
Immunogen:
This SREBP-2 antibody was raised against a recombinant protein corresponding to amino acids 833-1141 of human SREBP-2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
IgG-1C6
Conjugate:
Unconjugated
Gene:
SREBF2
Gene Alias:
AI608257; BHLHD2; Class D basic helix-loop-helix protein 2; EMBL:AAI01903.1}; lop13; nuc; Processed sterol regulatory element-binding protein 2; srebf2; srebf2 {ECO:0000312; Srebf2_retired; SREBP2; SREBP-2; SREBP2gc; sterol regulatory element binding factor 2; sterol regulatory element binding protein 2; sterol regulatory element binding transcription factor 2; Sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2; zgc:158371
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6721
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SREBP-2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.: Q12772
Gene Symbols: SREBF2
Immunogen: This SREBP-2 antibody was raised against a recombinant protein corresponding to amino acids 833-1141 of human SREBP-2.
Quantity: 10 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: IgG-1C6
Conjugate: Unconjugated
Gene: SREBF2
Gene Alias: AI608257; BHLHD2; Class D basic helix-loop-helix protein 2; EMBL:AAI01903.1}; lop13; nuc; Processed sterol regulatory element-binding protein 2; srebf2; srebf2 {ECO:0000312; Srebf2_retired; SREBP2; SREBP-2; SREBP2gc; sterol regulatory element binding factor 2; sterol regulatory element binding protein 2; sterol regulatory element binding transcription factor 2; Sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2; zgc:158371
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6721
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SREBP-2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Accession No.:
Q12772
Gene Symbols:
SREBF2
Immunogen:
This SREBP-2 antibody was raised against a recombinant protein corresponding to amino acids 833-1141 of human SREBP-2.
Quantity:
10 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
IgG-1C6
Conjugate:
Unconjugated
Gene:
SREBF2
Gene Alias:
AI608257; BHLHD2; Class D basic helix-loop-helix protein 2; EMBL:AAI01903.1}; lop13; nuc; Processed sterol regulatory element-binding protein 2; srebf2; srebf2 {ECO:0000312; Srebf2_retired; SREBP2; SREBP-2; SREBP2gc; sterol regulatory element binding factor 2; sterol regulatory element binding protein 2; sterol regulatory element binding transcription factor 2; Sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2; zgc:158371
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6721
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid