50-199-3004

Lamin A, mature Monoclonal Antibody (4A4), Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-3004-Each-of-1 In Stock ₹ 12,834.00

50-199-3004 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

Lamin A, mature

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.

P02545

Gene Symbols

LMNA

Immunogen

This Lamin A, mature antibody was raised against a peptide within the C-terminus of mature human Lamin A.

Quantity

10 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

4A4

Conjugate

Unconjugated

Gene

LMNA

Gene Alias

70 kDa lamin; BOS_2775; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A; lamin A/C; lamin A/C-like 1; lamin C; lamin C2; Lamin-A/C; LDP1; LFP; LGMD1B; Lmn1; LMNA; LMNC; LMNL1; OTTHUMP00000015843; OTTHUMP00000015846; OTTHUMP00000015847; Prelamin-A/C; PRO1; Renal carcinoma antigen NY-REN-32

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

4000

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane
  • Two main subtypes of nuclear lamins can be distinguished, i.e
  • A-type lamins and B-type lamins
  • The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e
  • lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e
  • lamin B1 and lamin B2
  • Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy
  • In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.

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Img

Fischer Scientific

50-199-3004

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Antigen:
Lamin A, mature

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P02545

Gene Symbols:
LMNA

Immunogen:
This Lamin A, mature antibody was raised against a peptide within the C-terminus of mature human Lamin A.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
4A4

Conjugate:
Unconjugated

Gene:
LMNA

Gene Alias:
70 kDa lamin; BOS_2775; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A; lamin A/C; lamin A/C-like 1; lamin C; lamin C2; Lamin-A/C; LDP1; LFP; LGMD1B; Lmn1; LMNA; LMNC; LMNL1; OTTHUMP00000015843; OTTHUMP00000015846; OTTHUMP00000015847; Prelamin-A/C; PRO1; Renal carcinoma antigen NY-REN-32

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4000

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3007

--


Antigen:
Progerin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P02545

Gene Symbols:
LMNA

Immunogen:
This Progerin antibody was raised against a peptide corresponding to amino acids 604-611 of human Progerin.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
13A4

Conjugate:
Unconjugated

Gene:
LMNA

Gene Alias:
70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4000

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3008

--


Antigen:
Progerin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P02545

Gene Symbols:
LMNA

Immunogen:
This Progerin antibody was raised against a peptide corresponding to amino acids 604-611 of human Progerin.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
13A4

Conjugate:
Unconjugated

Gene:
LMNA

Gene Alias:
70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4000

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Active Motif

50-199-3014

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Antigen:
DAX-1 / NR0B1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Accession No.:
P51843, P70503, Q61066

Gene Symbols:
NR0B1

Immunogen:
This DAX-1 / NR0B1 antibody was raised against a peptide corresponding to amino acids 135-166 of human DAX-1 / NR0B1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Clone:
1DA-2F4

Conjugate:
Unconjugated

Gene:
NR0B1

Gene Alias:
adrenal hypoplasia, congenital homolog; AHC; Ahch; AHX; BOS_26183; DAX; DAX 1; DAX1; DAX-1; DSS; DSS-AHC critical region on the X chromosome protein 1; GTD; HHG; NR0B1; NROB1; nuclear hormone receptor; Nuclear receptor DAX-1; Nuclear receptor subfamily 0 group B member 1; nuclear receptor subfamily 0, group B, member 1; orphan nuclear receptor DAX-1; R0B1; SRXY2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11614, 190, 58850

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid