50-199-3311

MLL / HRX Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-3311-Each-of-1 In Stock ₹ 51,490.01

50-199-3311 - Each of 1

₹ 51,490.01

In Stock

Quantity

1

Base Price: ₹ 51,490.01

GST (18%): ₹ 9,268.202

Total Price: ₹ 60,758.212

Antigen

MLL / HRX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KMT2A

Gene Alias

ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; Histone-lysine N-methyltransferase 2A; HRX; HTRX; HTRX1; KMT2A; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; Lysine N-methyltransferase 2A; mixed lineage leukemia 1; MLL; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; Trithorax-like protein; TRX1; WDSTS; Zinc finger protein HRX

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

214162, 4297

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence

Concentration

Lot-Specific

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.

P55200, Q03164

Gene Symbols

KMT2A

Immunogen

This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 2829-2883 of human MLL.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Fischer Scientific

50-199-3312

--

Img

Fischer Scientific

50-199-2887

--

Img

Fischer Scientific

50-199-2888

--

Img

Fischer Scientific

50-199-2925

--

Img

Fischer Scientific

50-199-2924

--

Img

Fischer Scientific

50-199-3017

--

Img

Fischer Scientific

50-199-3018

--

Img

Fischer Scientific

50-199-3253

--

Description

  • KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis
  • It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac)
  • In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation
  • KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity
  • It has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', and has higher activity toward H3 acetylated on 'Lys-9'
  • Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-199-3311

--


Antigen:
MLL / HRX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KMT2A

Gene Alias:
ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; Histone-lysine N-methyltransferase 2A; HRX; HTRX; HTRX1; KMT2A; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; Lysine N-methyltransferase 2A; mixed lineage leukemia 1; MLL; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; Trithorax-like protein; TRX1; WDSTS; Zinc finger protein HRX

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
214162, 4297

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence

Concentration:
Lot-Specific

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
P55200, Q03164

Gene Symbols:
KMT2A

Immunogen:
This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 2829-2883 of human MLL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-3312

--


Antigen:
MLL / HRX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KMT2A

Gene Alias:
ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; Histone-lysine N-methyltransferase 2A; HRX; HTRX; HTRX1; KMT2A; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; Lysine N-methyltransferase 2A; mixed lineage leukemia 1; MLL; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; Trithorax-like protein; TRX1; WDSTS; Zinc finger protein HRX

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
214162, 4297

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence

Concentration:
Lot-Specific

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
P55200, Q03164

Gene Symbols:
KMT2A

Immunogen:
This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 2829-2883 of human MLL.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-3313

--


Antigen:
KLF6

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Klf6

Gene Alias:
Aa1017; AI448727; BCD1; B-cell-derived protein 1; C86813; CBA1; COPEB; core promoter element binding protein; Core promoter element-binding protein; CPBP; FM2; FM6; GBF; GC-rich binding factor; GC-rich sites-binding factor GBF; Ierepo1; Ierepo3; immediate early response, erythropoietin 1; KLF6; Krueppel-like factor 6; Kruppel like factor 6; Kruppel-like factor 6; Kruppel-like zinc finger protein Zf9; PAC1; Proto-oncogene BCD1; protooncogene B-cell derived 1; R75280; ST12; suppression of tumorigenicity 12 (prostate); Suppressor of tumorigenicity 12 protein; Transcription factor Zf9; ZF9

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1316

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q99612

Gene Symbols:
Klf6

Immunogen:
This kLF6 antibody was raised against a recombinant protein corresponding to amino acids 28-199 of human kruppel-like factor 6 (kLF6).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

Fischer Scientific

50-199-3314

--


Antigen:
KLF6

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Klf6

Gene Alias:
Aa1017; AI448727; BCD1; B-cell-derived protein 1; C86813; CBA1; COPEB; core promoter element binding protein; Core promoter element-binding protein; CPBP; FM2; FM6; GBF; GC-rich binding factor; GC-rich sites-binding factor GBF; Ierepo1; Ierepo3; immediate early response, erythropoietin 1; KLF6; Krueppel-like factor 6; Kruppel like factor 6; Kruppel-like factor 6; Kruppel-like zinc finger protein Zf9; PAC1; Proto-oncogene BCD1; protooncogene B-cell derived 1; R75280; ST12; suppression of tumorigenicity 12 (prostate); Suppressor of tumorigenicity 12 protein; Transcription factor Zf9; ZF9

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1316

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q99612

Gene Symbols:
Klf6

Immunogen:
This kLF6 antibody was raised against a recombinant protein corresponding to amino acids 28-199 of human kruppel-like factor 6 (kLF6).

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a