50-199-3322
Phospho-RNA pol II CTD (Thr4) Polyclonal Antibody, Active Motif™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-199-3322-Each-of-1 | In Stock | ₹ 50,480.40 |
50-199-3322 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,480.40
GST (18%): ₹ 9,086.472
Total Price: ₹ 59,566.872
Antigen
Phospho-RNA pol II CTD (Thr4)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
POLR2A
Gene Alias
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5430
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Dot Blot, Western Blot
Concentration
Lot-Specific
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.
P24928
Gene Symbols
POLR2A
Immunogen
This RNA Pol II CTD phospho Thr4 antibody was raised against a peptide containing the RNA Pol II CTD sequence phosphorylated at threonine 4.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- DNA-directed RNA polymerase II subunit RPB1 (POLR1A) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
- POLR1A is the largest subunit and is a catalytic component of RNA polymerase II which synthesizes mRNA precurors and many functional non-coding RNAs
- It also forms the polymerase active center together with the second largest subunit
- Pol II is the central component of the basal RNA polymerase II transcription machinery
- It is composed of mobile elements that move relative to each other
- RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft, and the jaws that are though to grab the incoming DNA template
- At the start of transcription, a single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II
- A bridging helix emanates from RPB1 and crosses the cleft near the catalytic stie and is through to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition
- During transcription elongation, Pol II moves on the template as the transcript elongates
- Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II's largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination, and mRNA processing
- Regulation of gene expression levels depends on the balance between methylation and acetylation levelts of the CTD-lysines.
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Antigen: Phospho-RNA pol II CTD (Thr4)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: POLR2A
Gene Alias: 220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5430
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Dot Blot, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: P24928
Gene Symbols: POLR2A
Immunogen: This RNA Pol II CTD phospho Thr4 antibody was raised against a peptide containing the RNA Pol II CTD sequence phosphorylated at threonine 4.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-RNA pol II CTD (Thr4)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
POLR2A
Gene Alias:
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5430
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Dot Blot, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
P24928
Gene Symbols:
POLR2A
Immunogen:
This RNA Pol II CTD phospho Thr4 antibody was raised against a peptide containing the RNA Pol II CTD sequence phosphorylated at threonine 4.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-RNA pol II CTD (Thr4)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: POLR2A
Gene Alias: 220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5430
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Dot Blot, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: P24928
Gene Symbols: POLR2A
Immunogen: This RNA Pol II CTD phospho Thr4 antibody was raised against a peptide containing the RNA Pol II CTD sequence phosphorylated at threonine 4.
Quantity: 10 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-RNA pol II CTD (Thr4)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
POLR2A
Gene Alias:
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5430
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Dot Blot, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
P24928
Gene Symbols:
POLR2A
Immunogen:
This RNA Pol II CTD phospho Thr4 antibody was raised against a peptide containing the RNA Pol II CTD sequence phosphorylated at threonine 4.
Quantity:
10 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FOXP1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: FOXP1
Gene Alias: 12CC4; 3110052D19Rik; 4932443N09Rik; AI461938; AW494214; FLJ23741; fork head-related protein like B; forkhead box P1; Forkhead box protein P1; Forkhead-related transcription factor 1; FOXP1; glutamine-rich factor 1; hFKH1B; HSPC215; Mac-1-regulated forkhead; MFH; MGC12942; MGC88572; MGC99551; QRF1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 108655
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ChIP Assay, Gel Shift, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: P58462
Gene Symbols: FOXP1
Immunogen: This FOXP1 antibody was raised against a recombinant protein corresponding to amino acids 495-578 of mouse FOXP1. This antibody detects three isoforms.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
FOXP1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
FOXP1
Gene Alias:
12CC4; 3110052D19Rik; 4932443N09Rik; AI461938; AW494214; FLJ23741; fork head-related protein like B; forkhead box P1; Forkhead box protein P1; Forkhead-related transcription factor 1; FOXP1; glutamine-rich factor 1; hFKH1B; HSPC215; Mac-1-regulated forkhead; MFH; MGC12942; MGC88572; MGC99551; QRF1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
108655
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ChIP Assay, Gel Shift, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
P58462
Gene Symbols:
FOXP1
Immunogen:
This FOXP1 antibody was raised against a recombinant protein corresponding to amino acids 495-578 of mouse FOXP1. This antibody detects three isoforms.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1
Antigen: Histone H2BK15ac
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2BC12
Gene Alias: 2610022J01Rik; Acetyl-Histone H2; Acetyl-Histone H2B K15; Acetyl-Histone H2B Lys15; AV127319; dJ193B12.2; dJ221C16.3; dJ221C16.8; GL105; H2B; H2b 613; H2B GL105; H2B histone family, member A; H2B histone family, member D; H2B histone family, member K; H2B histone family, member L; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member S; H2B histone family, member T; H2B K; H2B.1; H2B.1A; H2B.2; H2B/a; H2B/d; H2B/g; H2B/h; H2B/I; H2B/k; H2B/l; H2B/n; H2B/o; H2B/q; H2B/s; H2B/t; H2b-613; H2BC10; H2BC4; H2BC6; H2BC7; H2bc8; H2BFA; H2BFAiii; H2BFD; H2BFG; H2BFH; H2BFK; H2BFL; H2BFN; H2BFO; H2BFQ; H2bfs; H2BFT; H2BGL105; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2BLys15ac; H2BQ; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRIP1; Hist1h2ba; Hist1h2bc; Hist1h2be; HIST1H2BF; HIST1H2BG; HIST1H2BI; Hist1h2bk; HIST1H2BN; HIST1H2BO; HIST1H3I; HIST2H2BC; HIST2H2BD; HIST2H2BE; HIST2H2BF; histone 1, H2ba; histone 1, H2bc; histone 1, H2bg; histone 1, H2bi; histone 1, H2bk; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone cluster 1, H2ba; histone cluster 1, H2bc; histone cluster 1, H2bg; histone cluster 1, H2bi; histone cluster 1, H2bk; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 2, H2bc (pseudogene); histone cluster 2, H2bd (pseudogene); histone cluster 2, H2be; histone cluster 2, H2bf; histone family member; histone H2B; Histone H2B type 1-A; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; Histone H2B type 1-K; Histone H2B type 1-N; Histone H2B type 1-O; Histone H2B type 2-E; Histone H2B type 2-F; Histone H2B, testis; Histone H2B.1 A; Histone H2B.2; Histone H2B.a; Histone H2B.d; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.k; Histone H2B.l; Histone H2B.n; Histone H2B.q; Histone H2B-GL105; MGC125414; MGC125415; MGC125416; MGC9388; R74621; RP1-193B12.10; T25626; testis-specific histone 2b; Testis-specific histone H2B; Th2b
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 337873, 337874, 440689, 8339, 8341, 8346, 8347, 8348, 8349, 85236
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Dot Blot, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.: O60814, P23527, P62807, Q16778, Q5QNW6, Q6DN03, Q6DRA6, Q99877
Gene Symbols: H2BC10, H2BC12, H2BC15, H2BC17, H2BC18, H2BC19P, H2BC20P, H2BC21, H2BC4, H2BC8
Immunogen: This antibody was raised against a peptide including acetyl-lysine 15 of human histone H2B.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2BK15ac
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2BC12
Gene Alias:
2610022J01Rik; Acetyl-Histone H2; Acetyl-Histone H2B K15; Acetyl-Histone H2B Lys15; AV127319; dJ193B12.2; dJ221C16.3; dJ221C16.8; GL105; H2B; H2b 613; H2B GL105; H2B histone family, member A; H2B histone family, member D; H2B histone family, member K; H2B histone family, member L; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member S; H2B histone family, member T; H2B K; H2B.1; H2B.1A; H2B.2; H2B/a; H2B/d; H2B/g; H2B/h; H2B/I; H2B/k; H2B/l; H2B/n; H2B/o; H2B/q; H2B/s; H2B/t; H2b-613; H2BC10; H2BC4; H2BC6; H2BC7; H2bc8; H2BFA; H2BFAiii; H2BFD; H2BFG; H2BFH; H2BFK; H2BFL; H2BFN; H2BFO; H2BFQ; H2bfs; H2BFT; H2BGL105; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2BLys15ac; H2BQ; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRIP1; Hist1h2ba; Hist1h2bc; Hist1h2be; HIST1H2BF; HIST1H2BG; HIST1H2BI; Hist1h2bk; HIST1H2BN; HIST1H2BO; HIST1H3I; HIST2H2BC; HIST2H2BD; HIST2H2BE; HIST2H2BF; histone 1, H2ba; histone 1, H2bc; histone 1, H2bg; histone 1, H2bi; histone 1, H2bk; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone cluster 1, H2ba; histone cluster 1, H2bc; histone cluster 1, H2bg; histone cluster 1, H2bi; histone cluster 1, H2bk; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 2, H2bc (pseudogene); histone cluster 2, H2bd (pseudogene); histone cluster 2, H2be; histone cluster 2, H2bf; histone family member; histone H2B; Histone H2B type 1-A; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; Histone H2B type 1-K; Histone H2B type 1-N; Histone H2B type 1-O; Histone H2B type 2-E; Histone H2B type 2-F; Histone H2B, testis; Histone H2B.1 A; Histone H2B.2; Histone H2B.a; Histone H2B.d; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.k; Histone H2B.l; Histone H2B.n; Histone H2B.q; Histone H2B-GL105; MGC125414; MGC125415; MGC125416; MGC9388; R74621; RP1-193B12.10; T25626; testis-specific histone 2b; Testis-specific histone H2B; Th2b
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
337873, 337874, 440689, 8339, 8341, 8346, 8347, 8348, 8349, 85236
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Dot Blot, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Accession No.:
O60814, P23527, P62807, Q16778, Q5QNW6, Q6DN03, Q6DRA6, Q99877
Gene Symbols:
H2BC10, H2BC12, H2BC15, H2BC17, H2BC18, H2BC19P, H2BC20P, H2BC21, H2BC4, H2BC8
Immunogen:
This antibody was raised against a peptide including acetyl-lysine 15 of human histone H2B.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG