50-199-3363

JMJD3 / KDM6B Monoclonal Antibody (67-A2), Active Motif™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-3363-Each-of-1 In Stock ₹ 50,480.40

50-199-3363 - Each of 1

₹ 50,480.40

In Stock

Quantity

1

Base Price: ₹ 50,480.40

GST (18%): ₹ 9,086.472

Total Price: ₹ 59,566.872

Antigen

JMJD3 / KDM6B

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.

O15054, Q5NCY0

Gene Symbols

KDM6B

Immunogen

This antibody was raised against a recombinant protein corresponding to amino acids 1028-1684 of human JMJD3 / kDM6B.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

67-A2

Conjugate

Unconjugated

Gene

KDM6B

Gene Alias

1700064E03Rik; BC038313; JmjC domain-containing protein 3; Jmjd3; jumonji domain containing 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing 3; Jumonji domain-containing protein 3; KDM1 lysine (K)-specific demethylase 6B; Kdm6b; Kiaa0346; lysine (K)-specific demethylase 6B; Lysine demethylase 6B; Lysine-specific demethylase 6B; mKIAA0346

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

216850, 23135

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Covalent modification of histones plays critical role in regulating chromatin structure and transcription
  • While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones
  • A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function
  • Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate
  • Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9)
  • Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.

Compare Similar Items

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Img

Fischer Scientific

50-199-3363

--


Antigen:
JMJD3 / KDM6B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
O15054, Q5NCY0

Gene Symbols:
KDM6B

Immunogen:
This antibody was raised against a recombinant protein corresponding to amino acids 1028-1684 of human JMJD3 / kDM6B.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
67-A2

Conjugate:
Unconjugated

Gene:
KDM6B

Gene Alias:
1700064E03Rik; BC038313; JmjC domain-containing protein 3; Jmjd3; jumonji domain containing 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing 3; Jumonji domain-containing protein 3; KDM1 lysine (K)-specific demethylase 6B; Kdm6b; Kiaa0346; lysine (K)-specific demethylase 6B; Lysine demethylase 6B; Lysine-specific demethylase 6B; mKIAA0346

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
216850, 23135

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3364

--


Antigen:
JMJD3 / KDM6B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
O15054, Q5NCY0

Gene Symbols:
KDM6B

Immunogen:
This antibody was raised against a recombinant protein corresponding to amino acids 1028-1684 of human JMJD3 / kDM6B.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
67-A2

Conjugate:
Unconjugated

Gene:
KDM6B

Gene Alias:
1700064E03Rik; BC038313; JmjC domain-containing protein 3; Jmjd3; jumonji domain containing 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing 3; Jumonji domain-containing protein 3; KDM1 lysine (K)-specific demethylase 6B; Kdm6b; Kiaa0346; lysine (K)-specific demethylase 6B; Lysine demethylase 6B; Lysine-specific demethylase 6B; mKIAA0346

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
216850, 23135

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3365

--


Antigen:
Tet2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q6N021

Gene Symbols:
TET2

Immunogen:
This antibody was raised against a recombinant protein corresponding to amino acids 1-300 of human Tet2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunoprecipitation, Western Blot

Clone:
21F11

Conjugate:
Unconjugated

Gene:
TET2

Gene Alias:
Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; Methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; Tet2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
54790

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3366

--


Antigen:
Tet2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q6N021

Gene Symbols:
TET2

Immunogen:
This antibody was raised against a recombinant protein corresponding to amino acids 1-300 of human Tet2.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunoprecipitation, Western Blot

Clone:
21F11

Conjugate:
Unconjugated

Gene:
TET2

Gene Alias:
Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; Methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; Tet2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
54790

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid