50-199-3409

SETD7 / SET7 Polyclonal Antibody, Active Motif™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-199-3409-Each-of-1 In Stock ₹ 12,834.00

50-199-3409 - Each of 1

₹ 12,834.00

In Stock

Quantity

1

Base Price: ₹ 12,834.00

GST (18%): ₹ 2,310.12

Total Price: ₹ 15,144.12

Antigen

SETD7 / SET7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Setd7

Gene Alias

1600028F23Rik; FLJ21193; H3-K4 methyltransferase; H3-K4-HMTase; H3-K4-HMTase SETD7; H3K4MT; Histone H3-K4 methyltransferase SETD7; histone H3-lysine 4-specific methyltransferase; Histone-lysine N-methyltransferase SETD7; Kiaa1717; KMT7; Lysine N-methyltransferase 7; mKIAA1717; OTTHUMP00000220049; SET domain containing (lysine methyltransferase) 7; SET domain containing lysine methyltransferase 7; SET domain-containing protein 7; Set7; SET7/9; Set9; Setd7

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

80854

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

Lot-Specific

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.

Q8WTS6

Gene Symbols

Setd7

Immunogen

This antibody was raised against a peptide within human SETD7 / SET7.

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3
  • H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation
  • Plays a central role in the transcriptional activation of genes such as collagenase or insulin
  • Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription
  • Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins
  • Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II
  • Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation
  • Also able to demethylated 'Lys-372' of p53/TP53 in vitro.

Compare Similar Items

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Img

Fischer Scientific

50-199-3409

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Antigen:
SETD7 / SET7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Setd7

Gene Alias:
1600028F23Rik; FLJ21193; H3-K4 methyltransferase; H3-K4-HMTase; H3-K4-HMTase SETD7; H3K4MT; Histone H3-K4 methyltransferase SETD7; histone H3-lysine 4-specific methyltransferase; Histone-lysine N-methyltransferase SETD7; Kiaa1717; KMT7; Lysine N-methyltransferase 7; mKIAA1717; OTTHUMP00000220049; SET domain containing (lysine methyltransferase) 7; SET domain containing lysine methyltransferase 7; SET domain-containing protein 7; Set7; SET7/9; Set9; Setd7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80854

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q8WTS6

Gene Symbols:
Setd7

Immunogen:
This antibody was raised against a peptide within human SETD7 / SET7.

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-199-3410

--


Antigen:
O-GlcNAc

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
GlcNAc

Host Species:
Mouse

Purification Method:
IgM

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
This antibody was raised against a peptide containing O-GlcNAc - serine. This antibody recognizes single O-GlcNAc residues in b-O-glycosidic linkage to serine and threonine.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Multi-species, Mouse, Rat

Product Type:
Antibody

Isotype:
IgM

Img

Fischer Scientific

50-199-3411

--


Antigen:
O-GlcNAc

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
GlcNAc

Host Species:
Mouse

Purification Method:
IgM

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
This antibody was raised against a peptide containing O-GlcNAc - serine. This antibody recognizes single O-GlcNAc residues in b-O-glycosidic linkage to serine and threonine.

Quantity:
10 μg

Primary or Secondary:
Primary

Target Species:
Human, Multi-species, Mouse, Rat

Product Type:
Antibody

Isotype:
IgM

Img

Fischer Scientific

50-199-3414

--


Antigen:
KDM1B / LSD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KDM1B

Gene Alias:
4632428N09Rik; AI482520; amine oxidase (flavin containing) domain 1; amine oxidase, flavin containing 1; Aof1; bA204B7.3; C6orf193; dJ298J15.2; Flavin-containing amine oxidase domain-containing protein 1; KDM1B; LOC100340794; LSD2; lysine (K)-specific demethylase 1B; lysine demethylase 1B; Lysine-specific histone demethylase 1B; Lysine-specific histone demethylase 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
218214

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Accession No.:
Q8CIG3

Gene Symbols:
KDM1B

Immunogen:
This antibody was raised against a peptide within the N-terminal region of mouse kDM1B / LSD2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG