50-199-3945

LSD1 / KDM1A Rabbit anti-Human, Mouse, Unconjugated, Polyclonal, Active Motif™

Manufacturer: Active Motif

Select a Size

Pack Size SKU Availability Price
Each of 1 50-199-3945-Each-of-1 In Stock ₹ 51,490.01

50-199-3945 - Each of 1

₹ 51,490.01

In Stock

Quantity

1

Base Price: ₹ 51,490.01

GST (18%): ₹ 9,268.202

Total Price: ₹ 60,758.212

Antigen

LSD1 / KDM1A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KDM1A

Gene Alias

1810043O07Rik; 5330429M20; AA408884; amine oxidase (flavin containing) domain 2; Aof2; BHC110; BOS_2431; BOS_26437; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; EBI; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; F-box-like/WD repeat-containing protein TBL1X; Flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; Lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RGD1563868; RP1-184J9.1; SMAP55; TBL1; Tbl1x; transducin (beta)-like 1 X-linked; transducin (beta)-like 1X-linked; transducin beta like 1 X-linked; transducin beta-like 1; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06; zgc:158242

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

ChIP Assay, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.

O60341, O60907, Q6ZQ88, Q9QXE7

Gene Symbols

KDM1A, TBL1X

Immunogen

This antibody was raised against full-length recombinant human LSD1 / kDM1A protein.

Regulatory Status

RUO

Gene ID (Entrez)

21372, 23028, 6907, 99982

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Active Motif

50-255-6792

--

Img

Qed Bioscience Inc

50-227-7982

--

Img

Qed Bioscience Inc

50-227-7988

--

Img

Qed Bioscience Inc

50-227-8179

--

Img

Qed Bioscience Inc

50-227-8191

--

Img

Rockland Immunochemicals

50-194-3767

--

Img

Qed Bioscience Inc

50-227-7915

--

Img

Qed Bioscience Inc

50-227-7916

--

Description

  • LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor
  • LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain
  • This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase
  • It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed
  • LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3
  • This protein may play a role in the repression of neuronal genes
  • Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity
  • It may also demethylate 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to derepression of androgen receptor target genes
  • Mutations affecting this gene can result in cleft palate, psychomotor retardation, and distintive facial features.

Compare Similar Items

Show Difference

Img

Active Motif

50-199-3945

--


Antigen:
LSD1 / KDM1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KDM1A

Gene Alias:
1810043O07Rik; 5330429M20; AA408884; amine oxidase (flavin containing) domain 2; Aof2; BHC110; BOS_2431; BOS_26437; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; EBI; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; F-box-like/WD repeat-containing protein TBL1X; Flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; Lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RGD1563868; RP1-184J9.1; SMAP55; TBL1; Tbl1x; transducin (beta)-like 1 X-linked; transducin (beta)-like 1X-linked; transducin beta like 1 X-linked; transducin beta-like 1; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06; zgc:158242

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
O60341, O60907, Q6ZQ88, Q9QXE7

Gene Symbols:
KDM1A, TBL1X

Immunogen:
This antibody was raised against full-length recombinant human LSD1 / kDM1A protein.

Regulatory Status:
RUO

Gene ID (Entrez):
21372, 23028, 6907, 99982

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3948

--


Antigen:
MEP50

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WDR77

Gene Alias:
2610003I18Rik; 2610312E17Rik; Ac2-269; Androgen receptor cofactor p44; C79984; HKMT1069; Mep50; MEP-50; Methylosome protein 50; MGC2722; Nbla10071; OTTHUMP00000013473; p44; p44/Mep50; RGD1310479; RP11-552M11.3; testis tissue sperm-binding protein Li 44a; WD repeat domain 77; WD repeat-containing protein 77; WD45; WDR77

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
Q9BQA1

Gene Symbols:
WDR77

Immunogen:
This MEP50 antibody was raised against full-length human MEP50 with an N-terminal His-Tag.

Regulatory Status:
RUO

Gene ID (Entrez):
79084

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3949

--


Antigen:
MEP50

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WDR77

Gene Alias:
2610003I18Rik; 2610312E17Rik; Ac2-269; Androgen receptor cofactor p44; C79984; HKMT1069; Mep50; MEP-50; Methylosome protein 50; MGC2722; Nbla10071; OTTHUMP00000013473; p44; p44/Mep50; RGD1310479; RP11-552M11.3; testis tissue sperm-binding protein Li 44a; WD repeat domain 77; WD repeat-containing protein 77; WD45; WDR77

Host Species:
Rabbit

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
Q9BQA1

Gene Symbols:
WDR77

Immunogen:
This MEP50 antibody was raised against full-length human MEP50 with an N-terminal His-Tag.

Regulatory Status:
RUO

Gene ID (Entrez):
79084

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

50-199-3954

--


Antigen:
Histone H2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
1190022L06; Acetyl-Histone H2; AW228881; BOS_14476; BOS_21793; BOS_6451; dJ160A22.4; dJ86C11.1; gammaH2ax; h2a; H2A 615 antibody; H2A GL101 antibody; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member X; H2A histone family, member Z; H2A.1; H2A.1 antibody; H2A.1b; H2A.2; H2A.3; H2a.x; H2A.z; H2a.z-1; H2A/a; H2A/c; H2A/d; H2A/E; H2A/g; H2A/m; H2A/p; H2A/S; H2a/x; H2A/z; H2a-291A; H2a-53; h2a-A; H2ac11; H2ac13; H2AC15; H2AC16; H2AC17; H2ae; H2AFA; H2AFALii; H2AFC; H2AFD; H2AFE; H2AFG; H2AFI; H2AFM; H2AFN; H2AFP; H2afx; H2AFZ; H2AG; H2AH; H2ak; H2AK5ac; H2ax; H2AX histone; H2az; H2AZ histone; HIS; Hist1h2aa; Hist1h2ab; Hist1h2ac; HIST1H2AD; HIST1H2AE; HIST1H2AE antibody; HIST1H2AG; Hist1h2ah; HIST1H2AI; HIST1H2AJ; HIST1H2AK; HIST1H2AL; HIST1H2AM; Hist1

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Yeast

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
This Histone H2A antibody was raised against recombinant yeast histone H2A.

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid