50-225-6760

PAX8 Rabbit anti-Human, CoraLite 488, Polyclonal, Proteintech

Manufacturer: Proteintech Group Inc

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Pack Size SKU Availability Price
Pack of 1 50-225-6760-Pack-of-1 In Stock ₹ 42,443.75

50-225-6760 - Pack of 1

₹ 42,443.75

In Stock

Quantity

1

Base Price: ₹ 42,443.75

GST (18%): ₹ 7,639.875

Total Price: ₹ 50,083.625

Antigen

PAX8

Classification

Polyclonal

Conjugate

CoraLite 488

Quantity

100 μL

Gene ID (Entrez)

7849

Form

Liquid

Applications

Immunofluorescence

Concentration

1000 μg/mL

Host Species

Rabbit

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG

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Description

  • PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain
  • It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system
  • It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas
  • PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243)
  • PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas
  • This antibody can detect all 5 isoforms of PAX8 (31 kDa, 34 kDa, 41 kDa, 43 kDa and 48 kDa)
  • A 58-60 kDa form has also been reported (PMID:15650356, 1049952)
  • Proteintech's 10336-1-AP antibody has cross-reactivities with the other PAX family members.

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Antigen:
PAX8

Classification:
Polyclonal

Conjugate:
CoraLite 488

Quantity:
100 μL

Gene ID (Entrez):
7849

Form:
Liquid

Applications:
Immunofluorescence

Concentration:
1000 μg/mL

Host Species:
Rabbit

Primary or Secondary:
Primary

Target Species:
Human

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IgG

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Antigen:
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Quantity:
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Gene ID (Entrez):
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__