50-245-798

CD11c Monoclonal Antibody (N418), eFluor™ 615, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 50-245-798-Each-of-1 In Stock ₹ 23,871.24

50-245-798 - Each of 1

₹ 23,871.24

In Stock

Quantity

1

Base Price: ₹ 23,871.24

GST (18%): ₹ 4,296.823

Total Price: ₹ 28,168.063

Antigen

CD11c

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q9QXH4

Gene Symbols

Itgax

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16411

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen)

Clone

N418

Conjugate

eFluor 615

Gene

Itgax

Gene Alias

AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6

Host Species

Armenian Hamster

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Description: The N418 monoclonal antibody reacts with mouse CD11c, the integrin alpha X
  • CD11c non-covalently associates with beta 2 integrin to form the CD11c/CD18 heterodimer
  • CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells
  • CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions
  • N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer
  • Applications Reported: This N418 antibody has been reported for use in immunohistochemical staining of frozen tissue sections and immunocytochemistry
  • Applications Tested: This N418 antibody has been tested by immunohistochemistry on frozen mouse spleen (IHC-F) at less than or equal to 5 μg/mL
  • It is recommended that this antibody be carefully titrated for optimal performance in the assay of interest
  • This product has not been validated for flow cytometric analysis
  • Filter Recommendation: When using this eFluor™ 615 antibody conjugate, we recommend a filter that will capture the 615 emission wavelength
  • (for example, Excitation 560/55, 585LP, Emission 645/75)
  • A standard Alexa Fluor™ 594 filter is acceptable
  • Excitation: 595 nm; Emission: 615 nm
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD11, along with CD18, form a heterodimer adhesion molecule
  • In particular, CD11 is composed of CD11a, CD11b and CD11c
  • CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils
  • CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes
  • CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.

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Invitrogen

50-245-798

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Antigen:
CD11c

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9QXH4

Gene Symbols:
Itgax

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16411

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen)

Clone:
N418

Conjugate:
eFluor 615

Gene:
Itgax

Gene Alias:
AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6

Host Species:
Armenian Hamster

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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eMolecules​

50-245-7981

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