50-252-9368

MMP2 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-252-9368-Each-of-1 In Stock ₹ 24,812.40

50-252-9368 - Each of 1

₹ 24,812.40

In Stock

Quantity

1

Base Price: ₹ 24,812.40

GST (18%): ₹ 4,466.232

Total Price: ₹ 29,278.632

Antigen

MMP2

Classification

Polyclonal

Formulation

PBS with no preservative

Gene Accession No.

P08253

Gene Symbols

MMP2

Immunogen

E.coli-derived, 62.0 kDa Recombinant Human MMP-2

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

Applications

ELISA, Western Blot

Conjugate

Biotin

Gene

MMP2

Gene Alias

72 kDa gelatinase, 72 kDa type IV collagenase, 72 kDa type IV collagenase isoform a preproprotein, 72kD gelatinase, 72kD type IV collagenase, 72kDa gelatinase, 72kDa type IV collagenase, CLG 4A, CLG4, CLG4A, Collagenase, collagenase type IV-A, endopeptidase, GelA, gelatinase A, Gelatinase alpha, Mat, matrix metallo protease, matrix metallopeptidase 2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloprotease 2, matrix metalloproteinase, matrix metalloproteinase 2, matrix metalloproteinase 2 (72 KDa type IV collagenase), matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloproteinase-2, matrix metalloproteinase-II, MMP, MMP2, MMP-2, MMP-2 protein, MMP-II, MMPs, MONA, neutrophil gelatinase, PEX, prepro-72kDa matrix metalloproteinase, Progelatinase A, TBE1, TBE-1, wu:fa99h12, wu:fk89d01

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4313

Content And Storage

-20°C

Description

  • AA Seq: MYNFFPRKPK WDKNQITYRI IGYTPDLDPE TVDDAFARAF QVWSDVTPLR FSRIHDGEAD IMINFGRWEH GDGYPFDGKD GLLAHAFAPG TGVGGDSHFD DDELWTLGEG QVVRVKYGNA DGEYCKFPFL FNGKEYNSCT DTGRSDGFLW CSTTYNFEKD GKYGFCPHEA LFTMGGNAEG QPCKFPFRFQ GTSYDSCTTE GRTDGYRWCG TTEDYDRDKK YGFCPETAMS TVGGNSEGAP CVFPFTFLGN KYESCTSAGR SDGKMWCATT ANYDDDRKWG FCPDQGYSLF LVAAHEFGHA MGLEHSQDPG ALMAPIYTYT KNFRLSQDDI KGIQELYGAS PDIDLGTGPT PTLGPVTPEI CKQDIVFDGI AQIRGEIFFF KDRFIWRTVT PRDKPMGPLL VATFWPELPE KIDAVYEAPQ EEKAVFFAGN EYWIYSASTL ERGYPKPLTS LGLPPDVQRV DAAFNWSKNK KTYIFAGDKF WRYNEVKKKM DPGFPKLIAD AWNAIPDNLD AVVDLQGGGH SYFFKGAYYL KLENQSLKSV KFGSIKSDWL GC Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MMP-2
  • Anti-Human MMP-2-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human MMP-2 by sandwich ELISA (using 100 μL/well) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human MMP-2 (500-P307) as a capture antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human MMP-2
  • Western Blot: To detect Human MMP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2μg/ml
  • When used in conjunction with compatible development reagents the detection limit for Recombinant Human MMP-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • MMP (matrix metalloproteinase) are proteolytic enzymes capable of degrading connective tissue components
  • MMP have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs)
  • MMPa and TIMPs play a significant role in regulating angiogenesis
  • MMP2 is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids, and contains the basic structure of propeptide, catalytic, and hemopexin domains
  • The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane-bound zincendopeptidases
  • Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non-fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins
  • In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc-binding site characterizes the structure of the MMPs
  • Functionally, MMP2 is involved in tissue remodeling
  • Mutations in MMP-2 gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome
  • Two transcript variants encoding different isoforms of MMP-2 have been found.

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Fischer Scientific

50-252-9368

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Antigen:
MMP2

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P08253

Gene Symbols:
MMP2

Immunogen:
E.coli-derived, 62.0 kDa Recombinant Human MMP-2

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Gene:
MMP2

Gene Alias:
72 kDa gelatinase, 72 kDa type IV collagenase, 72 kDa type IV collagenase isoform a preproprotein, 72kD gelatinase, 72kD type IV collagenase, 72kDa gelatinase, 72kDa type IV collagenase, CLG 4A, CLG4, CLG4A, Collagenase, collagenase type IV-A, endopeptidase, GelA, gelatinase A, Gelatinase alpha, Mat, matrix metallo protease, matrix metallopeptidase 2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloprotease 2, matrix metalloproteinase, matrix metalloproteinase 2, matrix metalloproteinase 2 (72 KDa type IV collagenase), matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloproteinase-2, matrix metalloproteinase-II, MMP, MMP2, MMP-2, MMP-2 protein, MMP-II, MMPs, MONA, neutrophil gelatinase, PEX, prepro-72kDa matrix metalloproteinase, Progelatinase A, TBE1, TBE-1, wu:fa99h12, wu:fk89d01

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4313

Content And Storage:
-20°C

Img

Fischer Scientific

50-252-9369

--


Antigen:
MMP2

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P08253

Gene Symbols:
MMP2

Immunogen:
E.coli-derived, 62.0 kDa Recombinant Human MMP-2

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Gene:
MMP2

Gene Alias:
72 kDa gelatinase, 72 kDa type IV collagenase, 72 kDa type IV collagenase isoform a preproprotein, 72kD gelatinase, 72kD type IV collagenase, 72kDa gelatinase, 72kDa type IV collagenase, CLG 4A, CLG4, CLG4A, Collagenase, collagenase type IV-A, endopeptidase, GelA, gelatinase A, Gelatinase alpha, Mat, matrix metallo protease, matrix metallopeptidase 2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloprotease 2, matrix metalloproteinase, matrix metalloproteinase 2, matrix metalloproteinase 2 (72 KDa type IV collagenase), matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloproteinase-2, matrix metalloproteinase-II, MMP, MMP2, MMP-2, MMP-2 protein, MMP-II, MMPs, MONA, neutrophil gelatinase, PEX, prepro-72kDa matrix metalloproteinase, Progelatinase A, TBE1, TBE-1, wu:fa99h12, wu:fk89d01

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4313

Content And Storage:
-20°C

Img

Fischer Scientific

50-252-9379

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Antigen:
IL-12 p70

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P29459, P29460

Gene Symbols:
IL12A, Il12b

Immunogen:
HEK293 cells-derived Recombinant Human IL-12 p70

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Gene:
IL12A

Gene Alias:
20C2, CLMF, CLMF p35, CLMF p40, CLMF2, cytokine, cytotoxic lymphocyte maturation factor 1, p35, cytotoxic lymphocyte maturation factor 35 kDa subunit, Cytotoxic lymphocyte maturation factor 40 kDa subunit, il 12, IL 12p70, Il12, IL-12, Il-12 p35, IL-12 p75, IL-12 subunit p35, IL-12 subunit p40, IL-12, subunit p35, IL12, subunit p40, Il-12, cytokine, IL12A, IL-12A, IL12A/B, IL12AB, IL12B, Il-12b, IL12P35, IL-12p35, Il12p40, Il-12p40, IL35 subunit, ILN, IMD28, IMD29, Interleukin, interleukin 12 35 kDa subunit, interleukin 12 35kDa subunit, interleukin 12 40 kDa subunit, interleukin 12 40kDa subunit, interleukin 12 p35 subunit, interleukin 12 p40 subunit precursor, interleukin 12 polypeptide 35, interleukin 12, p35, interleukin 12, p40, interleukin 12A, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35), interleukin 12B, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40), interleu

Host Species:
Goat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3592, 3593

Content And Storage:
-20°C

Img

Fischer Scientific

50-252-9380

--


Antigen:
IL-12 p70

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P29459, P29460

Gene Symbols:
IL12A, Il12b

Immunogen:
HEK293 cells-derived Recombinant Human IL-12 p70

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Gene:
Il12b

Gene Alias:
20C2, CLMF, CLMF p35, CLMF p40, CLMF2, cytokine, cytotoxic lymphocyte maturation factor 1, p35, cytotoxic lymphocyte maturation factor 35 kDa subunit, Cytotoxic lymphocyte maturation factor 40 kDa subunit, il 12, IL 12p70, Il12, IL-12, Il-12 p35, IL-12 p75, IL-12 subunit p35, IL-12 subunit p40, IL-12, subunit p35, IL12, subunit p40, Il-12, cytokine, IL12A, IL-12A, IL12A/B, IL12AB, IL12B, Il-12b, IL12P35, IL-12p35, Il12p40, Il-12p40, IL35 subunit, ILN, IMD28, IMD29, Interleukin, interleukin 12 35 kDa subunit, interleukin 12 35kDa subunit, interleukin 12 40 kDa subunit, interleukin 12 40kDa subunit, interleukin 12 p35 subunit, interleukin 12 p40 subunit precursor, interleukin 12 polypeptide 35, interleukin 12, p35, interleukin 12, p40, interleukin 12A, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35), interleukin 12B, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40), interleu

Host Species:
Goat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3592, 3593

Content And Storage:
-20°C