50-255-0874

IL-17A Monoclonal Antibody (eBio64CAP17), Functional Grade, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-255-0874-Each-of-1 In Stock ₹ 1,87,804.20

50-255-0874 - Each of 1

₹ 1,87,804.20

In Stock

Quantity

1

Base Price: ₹ 1,87,804.20

GST (18%): ₹ 33,804.756

Total Price: ₹ 2,21,608.956

Antigen

IL-17A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative, pH 7.2

Gene Accession No.

Q16552

Gene Symbols

IL17A

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3605

Content And Storage

4°, C

Form

Liquid

Applications

Functional Assay, Immunostaining, Neutralization

Clone

eBio64CAP17

Conjugate

Functional Grade

Gene

IL17A

Gene Alias

Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species

Mouse

Quantity

5 mg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Description

  • Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
  • IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
  • High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
  • In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
  • In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
  • Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
  • IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

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Img

Fischer Scientific

50-255-0874

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Antigen:
IL-17A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative, pH 7.2

Gene Accession No.:
Q16552

Gene Symbols:
IL17A

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3605

Content And Storage:
4°, C

Form:
Liquid

Applications:
Functional Assay, Immunostaining, Neutralization

Clone:
eBio64CAP17

Conjugate:
Functional Grade

Gene:
IL17A

Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species:
Mouse

Quantity:
5 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

50-255-0876

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Antigen:
Lamin A

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
P02545, P48678

Gene Symbols:
LMNA

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16905, 4000

Content And Storage:
4°, C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
4A4-A4

Conjugate:
Unconjugated

Gene:
LMNA

Gene Alias:
70 kDa lamin, CDCD1, CDDC, CMD1A, CMT2B1, Dhe, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, lamin, lamin A, lamin A/C, lamin A/C-like 1, lamin C, lamin C2, lamin-A/C, LDP1, LFP, LGMD1B, LMN1, Lmna, LMNA protein, LMNC, LMNL1, OTTHUMP00000015843, OTTHUMP00000015846, OTTHUMP00000015847, Prelamin-A/C, PRO1, renal carcinoma antigen NY-REN-32, unnamed protein product

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
__

Isotype:
IgG1 κ

Img

Bioworld

50-255-088

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

Fischer Scientific

50-255-0880

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Antigen:
CD271 (NGF Receptor)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P07174, P08138, Q9Z0W1

Gene Symbols:
Ngfr

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100349095, 100525607, 101119064, 18053, 24596, 4804, 491071

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
ME20.4

Conjugate:
Unconjugated

Gene:
Ngfr

Gene Alias:
CD271; CD271 antigen; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 16; low-affinity nerve growth factor receptor; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; NGFR; NGR; p75; p-75; p75 ICD; p75 neurotrophin receptor; p75 ntr; p75(NTR); p75NGFR; p75NTR; RNNGFRR; TNFR superfamily, member 16; Tnfrsf16; TNR16; Tumor necrosis factor receptor superfamily member 16

Host Species:
Mouse

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Ovine, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG1 κ