50-271-8525

MMP2 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-271-8525-Each-of-1 In Stock ₹ 1,68,767.10

50-271-8525 - Each of 1

₹ 1,68,767.10

In Stock

Quantity

1

Base Price: ₹ 1,68,767.10

GST (18%): ₹ 30,378.078

Total Price: ₹ 1,99,145.178

Antigen

MMP2

Classification

Polyclonal

Formulation

PBS with no preservative

Gene Accession No.

P08253

Gene Symbols

MMP2

Immunogen

E.coli-derived, 62.0 kDa Recombinant Human MMP-2

Quantity

500μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

Applications

Western Blot, ELISA

Conjugate

Biotin

Gene

MMP2

Gene Alias

72 kDa gelatinase, 72 kDa type IV collagenase, 72 kDa type IV collagenase isoform a preproprotein, 72kD gelatinase, 72kD type IV collagenase, 72kDa gelatinase, 72kDa type IV collagenase, CLG 4A, CLG4, CLG4A, Collagenase, collagenase type IV-A, endopeptidase, GelA, gelatinase A, Gelatinase alpha, Mat, matrix metallo protease, matrix metallopeptidase 2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloprotease 2, matrix metalloproteinase, matrix metalloproteinase 2, matrix metalloproteinase 2 (72 KDa type IV collagenase), matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloproteinase-2, matrix metalloproteinase-II, MMP, MMP2, MMP-2, MMP-2 protein, MMP-II, MMPs, MONA, neutrophil gelatinase, PEX, prepro-72kDa matrix metalloproteinase, Progelatinase A, TBE1, TBE-1, wu:fa99h12, wu:fk89d01

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4313

Content And Storage

-20°C

Isotype

IgG

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Description

  • AA Seq: MYNFFPRKPK WDKNQITYRI IGYTPDLDPE TVDDAFARAF QVWSDVTPLR FSRIHDGEAD IMINFGRWEH GDGYPFDGKD GLLAHAFAPG TGVGGDSHFD DDELWTLGEG QVVRVKYGNA DGEYCKFPFL FNGKEYNSCT DTGRSDGFLW CSTTYNFEKD GKYGFCPHEA LFTMGGNAEG QPCKFPFRFQ GTSYDSCTTE GRTDGYRWCG TTEDYDRDKK YGFCPETAMS TVGGNSEGAP CVFPFTFLGN KYESCTSAGR SDGKMWCATT ANYDDDRKWG FCPDQGYSLF LVAAHEFGHA MGLEHSQDPG ALMAPIYTYT KNFRLSQDDI KGIQELYGAS PDIDLGTGPT PTLGPVTPEI CKQDIVFDGI AQIRGEIFFF KDRFIWRTVT PRDKPMGPLL VATFWPELPE KIDAVYEAPQ EEKAVFFAGN EYWIYSASTL ERGYPKPLTS LGLPPDVQRV DAAFNWSKNK KTYIFAGDKF WRYNEVKKKM DPGFPKLIAD AWNAIPDNLD AVVDLQGGGH SYFFKGAYYL KLENQSLKSV KFGSIKSDWL GC Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MMP-2
  • Anti-Human MMP-2-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human MMP-2 by sandwich ELISA (using 100 μL/well) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human MMP-2 (500-P307) as a capture antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human MMP-2
  • Western Blot: To detect Human MMP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2μg/ml
  • When used in conjunction with compatible development reagents the detection limit for Recombinant Human MMP-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • MMP (matrix metalloproteinase) are proteolytic enzymes capable of degrading connective tissue components
  • MMP have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs)
  • MMPa and TIMPs play a significant role in regulating angiogenesis
  • MMP2 is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids, and contains the basic structure of propeptide, catalytic, and hemopexin domains
  • The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane-bound zincendopeptidases
  • Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non-fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins
  • In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc-binding site characterizes the structure of the MMPs
  • Functionally, MMP2 is involved in tissue remodeling
  • Mutations in MMP-2 gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome
  • Two transcript variants encoding different isoforms of MMP-2 have been found.

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Antigen:
MMP2

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P08253

Gene Symbols:
MMP2

Immunogen:
E.coli-derived, 62.0 kDa Recombinant Human MMP-2

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
Western Blot, ELISA

Conjugate:
Biotin

Gene:
MMP2

Gene Alias:
72 kDa gelatinase, 72 kDa type IV collagenase, 72 kDa type IV collagenase isoform a preproprotein, 72kD gelatinase, 72kD type IV collagenase, 72kDa gelatinase, 72kDa type IV collagenase, CLG 4A, CLG4, CLG4A, Collagenase, collagenase type IV-A, endopeptidase, GelA, gelatinase A, Gelatinase alpha, Mat, matrix metallo protease, matrix metallopeptidase 2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloprotease 2, matrix metalloproteinase, matrix metalloproteinase 2, matrix metalloproteinase 2 (72 KDa type IV collagenase), matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), matrix metalloproteinase-2, matrix metalloproteinase-II, MMP, MMP2, MMP-2, MMP-2 protein, MMP-II, MMPs, MONA, neutrophil gelatinase, PEX, prepro-72kDa matrix metalloproteinase, Progelatinase A, TBE1, TBE-1, wu:fa99h12, wu:fk89d01

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4313

Content And Storage:
-20°C

Isotype:
IgG

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Antigen:
EGFR

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P00533

Gene Symbols:
EGFR

Immunogen:
CHO cells-derived Recombinant Human EGF Receptor (EGFR)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
Western Blot, ELISA

Conjugate:
Biotin

Gene:
EGFR

Gene Alias:
2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1956

Content And Storage:
-20°C

Isotype:
IgG

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Antigen:
TRAIL

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P50592

Gene Symbols:
TNFSF10

Immunogen:
E.coli-derived, 20.0 kDa Recombinant Murine TRAIL

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

Applications:
Western Blot, ELISA

Conjugate:
Biotin

Gene:
TNFSF10

Gene Alias:
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22035

Content And Storage:
-20°C

Isotype:
IgG

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Antigen:
IL-9

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P15248

Gene Symbols:
Il9

Immunogen:
E.coli-derived Recombinant Human IL-9

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
Western Blot, ELISA

Conjugate:
Biotin

Gene:
Il9

Gene Alias:
cytokine P40; homolog of mouse T cell and mast cell growth factor 40; HP40; IL9; IL-9; ILN; Interleukin; interleukin 9; Interleukin9; interleukin-9; P40; p40 cytokine; p40 T-cell and mast cell growth factor; T-cell growth factor P40

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3578

Content And Storage:
-20°C

Isotype:
IgG