50-271-8605

CCL4 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-271-8605-Each-of-1 In Stock ₹ 1,68,767.10

50-271-8605 - Each of 1

₹ 1,68,767.10

In Stock

Quantity

1

Base Price: ₹ 1,68,767.10

GST (18%): ₹ 30,378.078

Total Price: ₹ 1,99,145.178

Antigen

CCL4

Classification

Polyclonal

Conjugate

Biotin

Gene

CCL4

Gene Alias

ACT2; ACT-2; AT744.1; CC chemokine ligand 4; C-C motif chemokine 4; C-C motif chemokine ligand 4; Ccl4; chemokine (C-C motif) ligand 4; G-26; G-26 T-lymphocyte-secreted protein; HC21; immune activation gene 2; immune activation gene-2; immune activation protein 2; LAG1; LAG-1; Lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1 beta; MGC104418; MGC126025; MGC126026; MIP-1 beta; MIP1b; MIP-1B; Mip1-b; MIP1B1; MIP1beta; MIP-1BETA; MIP-1-beta; MIP1-beta; MIP-1-beta(1-69); MIP-1-beta(3-69); PAT 744; Protein H400; putative MIP-1beta protein; RP23-320E6.8; SCY4A; SCYA2; Scya4; secreted protein G-26; SIS-gamma; small inducible cytokine A4; small inducible cytokine A4 (homologous to mouse Mip-1b); small-inducible cytokine A4; T-cell activation protein 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20303

Content And Storage

-20°C

Isotype

IgG

Applications

Western Blot, ELISA

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P14097

Gene Symbols

CCL4

Immunogen

E.coli-derived Recombinant Murine MIP-1beta (CCL4)

Quantity

500μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine MIP-1beta (CCL4)
  • Anti-Murine MIP-1beta (CCL4)-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Murine MIP-1beta by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine MIP-1beta (500-P213) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine MIP-1beta
  • Western Blot: To detect Murine MIP-1beta by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Murine MIP-1beta is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P213BT-1MG will be provided as 2 x 500 μg CCL4 (macrophage inflammatory protein 1-beta, MIP1B) belongs to the intercrine beta (chemokine CC) family
  • Functionally, CCL4 is involved in chemotactic and proinflammatory effects, and homeostasis
  • CCL4 is produced by macrophages upon stimulation by bacterial endotoxins
  • CCL4 recruits and stimulates various inflammatory cells at sites of inflammation
  • CCL4 is produced by lymphocytes, macrophages and dendritic cells
  • Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells
  • While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ, with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes
  • Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells
  • The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells
  • CCL4 binds with high affinity to CCR5 receptors.

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Antigen:
CCL4

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
CCL4

Gene Alias:
ACT2; ACT-2; AT744.1; CC chemokine ligand 4; C-C motif chemokine 4; C-C motif chemokine ligand 4; Ccl4; chemokine (C-C motif) ligand 4; G-26; G-26 T-lymphocyte-secreted protein; HC21; immune activation gene 2; immune activation gene-2; immune activation protein 2; LAG1; LAG-1; Lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1 beta; MGC104418; MGC126025; MGC126026; MIP-1 beta; MIP1b; MIP-1B; Mip1-b; MIP1B1; MIP1beta; MIP-1BETA; MIP-1-beta; MIP1-beta; MIP-1-beta(1-69); MIP-1-beta(3-69); PAT 744; Protein H400; putative MIP-1beta protein; RP23-320E6.8; SCY4A; SCYA2; Scya4; secreted protein G-26; SIS-gamma; small inducible cytokine A4; small inducible cytokine A4 (homologous to mouse Mip-1b); small-inducible cytokine A4; T-cell activation protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20303

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P14097

Gene Symbols:
CCL4

Immunogen:
E.coli-derived Recombinant Murine MIP-1beta (CCL4)

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

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Antigen:
WISP2

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
CCN5

Gene Alias:
CCN family member 5; CCN family protein COP-1; Ccn5; connective tissue growth factor-like protein; Connective tissue growth factor-related protein 58; Cop1; Crgr4; CT58; CTGFL; CTGF-L; Rcop1; UNQ228/PRO261; WISP2; WISP-2; WNT1 inducible signaling pathway protein 2; WNT1-inducible-signaling pathway protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8839

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O76076

Gene Symbols:
CCN5

Immunogen:
E.coli-derived Recombinant Human CTGFL/WISP-2

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

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Antigen:
IL-22

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL22

Gene Alias:
Cytokine Zcyto18; EGK_03903; il 22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; ILTIF; IL-TIF; ILTIF alpha; IL-TIF alpha; ILTIFa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50616

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9GZX6

Gene Symbols:
IL22

Immunogen:
E.coli-derived Recombinant Human IL-22

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

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Antigen:
IL-10

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL10

Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3586

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Western Blot, ELISA

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P22301

Gene Symbols:
IL10

Immunogen:
E.coli-derived Recombinant Human IL-10

Quantity:
500μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized