50-271-8621
IL-21 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-271-8621-Each-of-1 | In Stock | ₹ 1,68,767.10 |
50-271-8621 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,68,767.10
GST (18%): ₹ 30,378.078
Total Price: ₹ 1,99,145.178
Antigen
IL-21
Classification
Polyclonal
Conjugate
Biotin
Gene
IL21
Gene Alias
CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
59067
Content And Storage
-20°C
Isotype
IgG
Applications
Western Blot, ELISA
Concentration
0.1-1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q9HBE4
Gene Symbols
IL21
Immunogen
E.coli-derived Recombinant Human IL-21
Quantity
500μg
Primary or Secondary
Primary
Target Species
Human
Form
Lyophilized
Related Products
Description
- AA Sequence of recombinant protein: MQDRHMIRMR QLIDIVDQLK NYVNDLVPEF LPAPEDVETN CEWSAFSCFQ KAQLKSANTG NNERIINVSI KKLKRKPPST NAGRRQKHRL TCPSCDSYEK KPPKEFLERF KSLLQKMIHQ HLSSRTHGSE DS
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IL-21
- Anti-Human IL-21-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect hIL-21 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human IL-21 (500-P191) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hIL-21
- Western Blot: To detect Human IL-21 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human IL-21 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P191BT-1MG will be provided as 2 x 500 μg IL-21 is a 17 kDa immunomodulatory cytokine produced mainly by Natural Killer Cells (NKT), T helper (Th) 17 and T follicular helper (TFH) cells
- In TFH cells, IL-21 expression leads to autocrine signaling through the IL-21 receptor (IL-21R) and STAT3, which leads to additional transcriptional activation by Bcl6
- As with IFN gamma for Th1 and IL-4 for Th2 cells, IL-21 is critical for TFH cell development and effector function
- IL-21 plays a role in T cell-dependent B cell differentiation into plasma cells and memory cells, stimulation of IgG production and induction of apoptotic signaling in naive B cells
- In Th17 cells, IL-21 expression and autocrine feedback through STAT3, IRF4 and ROR gamma t lead to upregulation of the IL-23R, thereby preparing Th17 cells for maturation and maintenance by the inflammatory cytokine IL-23
- While upregulating IRF4 and ROR gamma t, IL-21 also mediates the downregulation of Foxp3
- IL-21 deficient mice are protected from developing colitis upon chemical treatment by their inability to upregulate Th17-associated molecules
- In comparison, elevated levels of IL-21 are present in chemically-induced colitis mouse models.
Compare Similar Items
Show Difference
Antigen: IL-21
Classification: Polyclonal
Conjugate: Biotin
Gene: IL21
Gene Alias: CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 59067
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9HBE4
Gene Symbols: IL21
Immunogen: E.coli-derived Recombinant Human IL-21
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
IL-21
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
IL21
Gene Alias:
CVID11; CX2; il 21; IL21; IL-21; ILN; Interleukin; interleukin 21; Interleukin21; interleukin-21; interleukin-21 isoform; porcine interleukin-21; Za11
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
59067
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9HBE4
Gene Symbols:
IL21
Immunogen:
E.coli-derived Recombinant Human IL-21
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: IL-20
Classification: Polyclonal
Conjugate: Biotin
Gene: Il20
Gene Alias: cytokine Zcyto10; four alpha helix cytokine; four alpha helix cytokine ZCYTO10; four helix bundle cytokine 10; il 20; IL10D; Il20; IL-20; ILN; Interleukin; interleukin 20; interleukin-20; MGC96907; PRO1801; UNQ852; UNQ852/PRO1801; ZCYTO10
Host Species: Goat
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 50604
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9NYY1
Gene Symbols: Il20
Immunogen: E.coli-derived Recombinant Human IL-20
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
IL-20
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
Il20
Gene Alias:
cytokine Zcyto10; four alpha helix cytokine; four alpha helix cytokine ZCYTO10; four helix bundle cytokine 10; il 20; IL10D; Il20; IL-20; ILN; Interleukin; interleukin 20; interleukin-20; MGC96907; PRO1801; UNQ852; UNQ852/PRO1801; ZCYTO10
Host Species:
Goat
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
50604
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9NYY1
Gene Symbols:
Il20
Immunogen:
E.coli-derived Recombinant Human IL-20
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: FGF2
Classification: Polyclonal
Conjugate: Biotin
Gene: FGF2
Gene Alias: Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2247
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P09038
Gene Symbols: FGF2
Immunogen: E.coli-derived Recombinant Human FGF-basic (154 a.a.)
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
FGF2
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
FGF2
Gene Alias:
Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2247
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P09038
Gene Symbols:
FGF2
Immunogen:
E.coli-derived Recombinant Human FGF-basic (154 a.a.)
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: IL-19
Classification: Polyclonal
Conjugate: Biotin
Gene: IL19
Gene Alias: il 19; IL-10C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG.1; ZMDA1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29949
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9UHD0
Gene Symbols: IL19
Immunogen: E.coli-derived Recombinant Human IL-19
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
IL-19
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
IL19
Gene Alias:
il 19; IL-10C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG.1; ZMDA1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29949
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9UHD0
Gene Symbols:
IL19
Immunogen:
E.coli-derived Recombinant Human IL-19
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized