50-271-8662
IL18BP Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-271-8662-Each-of-1 | In Stock | ₹ 1,68,767.10 |
50-271-8662 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,68,767.10
GST (18%): ₹ 30,378.078
Total Price: ₹ 1,99,145.178
Antigen
IL18BP
Classification
Polyclonal
Conjugate
Biotin
Gene
IL18BP
Gene Alias
Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa
Host Species
Goat
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16068
Content And Storage
-20°C
Isotype
IgG
Applications
Western Blot, ELISA
Concentration
0.1-1.0 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q9Z0M9
Gene Symbols
IL18BP
Immunogen
E.coli-derived Recombinant Murine IL-18BP
Quantity
500μg
Primary or Secondary
Primary
Target Species
Mouse
Form
Lyophilized
Related Products
Description
- Preparation: Produced from sera of goats immunized with highly pure Recombinant Murine IL-18BP
- Anti-Murine IL-18BP-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Murine IL-18BP by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine IL-18BP (500-P153G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine IL-18BP
- Western Blot: To detect mIL-18BP by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant mIL-18BP is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P153GBT-1MG will be provided as 2 x 500 μg Interleukin-18 binding protein (IL-18BP) is a constitutively secreted glycoprotein that acts as a natural antagonist for interleukin-18 (IL-18) by preventing interaction between IL-18 and its receptors
- Through this binding, IL-18BP neutralizes the proinflammatory role of IL-18 in cell-mediated immune responses, resulting in reduced IFN-gamma production by T helper type I cells and inhibition of allospecific cytotoxic T lymphocyte (CTL) activity through augmented natural killer (NK) cell cytotoxicity
- As an inhibitor of IL-18 and an essential component of skin homeostasis, IL-18BP has been linked to a variety of diseases, including eczema, asthma, and the autoimmune condition, Crohn's disease
- The upregulation of IL-18BP by keratinocytes expressing the human papillomavirus (HPV) E7 oncoprotein has been shown to decrease IL-18-induced IFN-gamma production and IL-18-mediated T cell activation
- Elevated levels of IL-18 and IL-18BP, as well as proinflammatory cytokines IFN-gamma, TNF-alpha, IL-1beta and IL-8, have been linked to chronic inflammation and observed in macrophages (including Kupffer cells) isolated from lesions and intestinal tissues of Crohn's disease patients
- As a member of the immunoglobulin-like class of receptors, IL-18BP contains a single immunoglobulin (Ig) domain; although two (b and d) of the four identified human isoforms (a-d) contain incomplete domains that greatly reduce their binding affinity.
Compare Similar Items
Show Difference
Antigen: IL18BP
Classification: Polyclonal
Conjugate: Biotin
Gene: IL18BP
Gene Alias: Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa
Host Species: Goat
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16068
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9Z0M9
Gene Symbols: IL18BP
Immunogen: E.coli-derived Recombinant Murine IL-18BP
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Lyophilized
Antigen:
IL18BP
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
IL18BP
Gene Alias:
Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa
Host Species:
Goat
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16068
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9Z0M9
Gene Symbols:
IL18BP
Immunogen:
E.coli-derived Recombinant Murine IL-18BP
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Lyophilized
Antigen: FGF17
Classification: Polyclonal
Conjugate: Biotin
Gene: FGF17
Gene Alias: FGF; FGF-13; FGF17; FGF-17; Fibroblast growth factor; Fibroblast growth factor 17; HH20; UNQ161/PRO187
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8822
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O60258
Gene Symbols: FGF17
Immunogen: E.coli-derived Recombinant Human FGF-17
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
FGF17
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
FGF17
Gene Alias:
FGF; FGF-13; FGF17; FGF-17; Fibroblast growth factor; Fibroblast growth factor 17; HH20; UNQ161/PRO187
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8822
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O60258
Gene Symbols:
FGF17
Immunogen:
E.coli-derived Recombinant Human FGF-17
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: FGF10
Classification: Polyclonal
Conjugate: Biotin
Gene: FGF10
Gene Alias: AEY17; BB213776; FGF; Fgf10; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Gsfaey17; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
Host Species: Goat
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2255
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O15520
Gene Symbols: FGF10
Immunogen: E.coli-derived Recombinant Human FGF-10
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
FGF10
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
FGF10
Gene Alias:
AEY17; BB213776; FGF; Fgf10; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Gsfaey17; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
Host Species:
Goat
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2255
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O15520
Gene Symbols:
FGF10
Immunogen:
E.coli-derived Recombinant Human FGF-10
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized
Antigen: TNFRSF11B
Classification: Polyclonal
Conjugate: Biotin
Gene: TNFRSF11B
Gene Alias: LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4982
Content And Storage: -20°C
Isotype: IgG
Applications: Western Blot, ELISA
Concentration: 0.1-1.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O00300
Gene Symbols: TNFRSF11B
Immunogen: E.coli-derived, 20.0 kDa Recombinant Human OPG
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Human
Form: Lyophilized
Antigen:
TNFRSF11B
Classification:
Polyclonal
Conjugate:
Biotin
Gene:
TNFRSF11B
Gene Alias:
LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4982
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Western Blot, ELISA
Concentration:
0.1-1.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O00300
Gene Symbols:
TNFRSF11B
Immunogen:
E.coli-derived, 20.0 kDa Recombinant Human OPG
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Lyophilized