50-271-8695
IGF1 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-271-8695-Each-of-1 | In Stock | ₹ 1,68,767.10 |
50-271-8695 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,68,767.10
GST (18%): ₹ 30,378.078
Total Price: ₹ 1,99,145.178
Antigen
IGF1
Classification
Polyclonal
Formulation
PBS with no preservative
Gene Accession No.
P05019
Gene Symbols
IGF1
Immunogen
E.coli-derived Recombinant Human IGF-I
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG
Applications
Western Blot, ELISA
Conjugate
Biotin
Gene
IGF1
Gene Alias
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3479
Form
Lyophilized
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Description
- AA Sequence of recombinant protein: GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-I
- Anti-Human IGF-I-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human IGF-I by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human IGF-I (500-P11) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IGF-I
- Western Blot: To detect hIGF-I by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant hIGF-I is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P11BT-1MG will be provided as 2 x 500 μg IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity
- A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival
- Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue
- IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake
- In circulation, IGFs are predominantly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues
- IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death
- Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins
- Low levels of IGF1 have been linked to Alzheimer's disease
- IGF1 is processed from a precursor, bound by a specific receptor, and secreted
- Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.
Compare Similar Items
Show Difference
Antigen: IGF1
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: P05019
Gene Symbols: IGF1
Immunogen: E.coli-derived Recombinant Human IGF-I
Quantity: 500 μg
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG
Applications: Western Blot, ELISA
Conjugate: Biotin
Gene: IGF1
Gene Alias: C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3479
Form: Lyophilized
Antigen:
IGF1
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
P05019
Gene Symbols:
IGF1
Immunogen:
E.coli-derived Recombinant Human IGF-I
Quantity:
500 μg
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG
Applications:
Western Blot, ELISA
Conjugate:
Biotin
Gene:
IGF1
Gene Alias:
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3479
Form:
Lyophilized
Antigen: CCL5 (RANTES)
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: P30882
Gene Symbols: CCL5
Immunogen: E.coli-derived, 7.8 kDa Recombinant Murine RANTES (CCL5)
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Mouse
Isotype: IgG
Applications: Western Blot, ELISA
Conjugate: Biotin
Gene: CCL5
Gene Alias: beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS d; SISd; SIS-delta; SISd; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20304
Form: Lyophilized
Antigen:
CCL5 (RANTES)
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
P30882
Gene Symbols:
CCL5
Immunogen:
E.coli-derived, 7.8 kDa Recombinant Murine RANTES (CCL5)
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Mouse
Isotype:
IgG
Applications:
Western Blot, ELISA
Conjugate:
Biotin
Gene:
CCL5
Gene Alias:
beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS d; SISd; SIS-delta; SISd; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20304
Form:
Lyophilized
Antigen: MIP-1 gamma
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: P51670
Gene Symbols: Ccl9
Immunogen: E.coli-derived Recombinant Murine MIP-1gamma (CCL9/10)
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Mouse
Isotype: IgG
Applications: Western Blot, ELISA
Conjugate: Biotin
Gene: Ccl9
Gene Alias: C-C motif chemokine 9; CCF18; Ccl9; CCL9(29-101); CCL9(30-101); CCL9(31-101); chemokine (C-C motif) ligand 9; chemokine CCL9; macrophage inflammatory protein 1-gamma; Macrophage inflammatory protein-related protein 2; MIP-1 gamma; MIP-1-gamma; Mrp2; MRP-2; RP23-320E6.3; Scya10; Scya9; small inducible cytokine A10; small inducible cytokine A9; Small-inducible cytokine A9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20308
Form: Lyophilized
Antigen:
MIP-1 gamma
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
P51670
Gene Symbols:
Ccl9
Immunogen:
E.coli-derived Recombinant Murine MIP-1gamma (CCL9/10)
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Mouse
Isotype:
IgG
Applications:
Western Blot, ELISA
Conjugate:
Biotin
Gene:
Ccl9
Gene Alias:
C-C motif chemokine 9; CCF18; Ccl9; CCL9(29-101); CCL9(30-101); CCL9(31-101); chemokine (C-C motif) ligand 9; chemokine CCL9; macrophage inflammatory protein 1-gamma; Macrophage inflammatory protein-related protein 2; MIP-1 gamma; MIP-1-gamma; Mrp2; MRP-2; RP23-320E6.3; Scya10; Scya9; small inducible cytokine A10; small inducible cytokine A9; Small-inducible cytokine A9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20308
Form:
Lyophilized
Antigen: MCP-3
Classification: Polyclonal
Formulation: PBS with no preservative
Gene Accession No.: Q03366
Gene Symbols: CCL7
Immunogen: E.coli-derived Recombinant Murine MCP-3 (CCL7)
Quantity: 500μg
Primary or Secondary: Primary
Target Species: Mouse
Isotype: IgG
Applications: Western Blot, ELISA
Conjugate: Biotin
Gene: CCL7
Gene Alias: C-C motif chemokine 7; C-C motif chemokine ligand 7; CCL7; chemokine (C-C motif) ligand 7; chemotactic protein-3; Fic; H-MCP-3; Intercrine/chemokine MARC; marc; Mcp3; MCP-3; MGC138463; MGC138465; Monocyte chemoattractant protein 3; monocyte chemotactic protein 3; NC28; Protein FIC; RANTES/sis homolog; RP23-350G1.4; SCYA6; Scya7; small inducible cytokine A7; small inducible cytokine A7 (monocyte chemotactic protein 3); small-inducible cytokine A7
Host Species: Goat
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20306
Form: Lyophilized
Antigen:
MCP-3
Classification:
Polyclonal
Formulation:
PBS with no preservative
Gene Accession No.:
Q03366
Gene Symbols:
CCL7
Immunogen:
E.coli-derived Recombinant Murine MCP-3 (CCL7)
Quantity:
500μg
Primary or Secondary:
Primary
Target Species:
Mouse
Isotype:
IgG
Applications:
Western Blot, ELISA
Conjugate:
Biotin
Gene:
CCL7
Gene Alias:
C-C motif chemokine 7; C-C motif chemokine ligand 7; CCL7; chemokine (C-C motif) ligand 7; chemotactic protein-3; Fic; H-MCP-3; Intercrine/chemokine MARC; marc; Mcp3; MCP-3; MGC138463; MGC138465; Monocyte chemoattractant protein 3; monocyte chemotactic protein 3; NC28; Protein FIC; RANTES/sis homolog; RP23-350G1.4; SCYA6; Scya7; small inducible cytokine A7; small inducible cytokine A7 (monocyte chemotactic protein 3); small-inducible cytokine A7
Host Species:
Goat
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20306
Form:
Lyophilized