50-553-337
LATS2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Manufacturer: Proteintech Group Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-553-337-Each-of-1 | In Stock | ₹ 42,443.75 |
50-553-337 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,443.75
GST (18%): ₹ 7,639.875
Total Price: ₹ 50,083.625
Antigen
LATS2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LATS2
Gene Alias
KPM, LATS2, Warts like kinase
Host Species
Rabbit
Purification Method
Antigen Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26524, 50523
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.27 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q7TSJ6, Q9NRM7
Gene Symbols
Lats2
Immunogen
Peptide
Quantity
150 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- LATS2 has a calculated molecular mass of 120 kDa and an apparent molecular mass of 150 kDa
- The antibody is specific to LATS2
- LATS2 is a serine/threonine kinase that serves as a negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
- The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
- Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
- LATS2 acts as a tumor supressor which plays a critical role in centrosome duplication, maintece of mitotic fidelity and genomic stability
- It negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity.
Compare Similar Items
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Antigen: LATS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LATS2
Gene Alias: KPM, LATS2, Warts like kinase
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26524, 50523
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.27 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q7TSJ6, Q9NRM7
Gene Symbols: Lats2
Immunogen: Peptide
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
LATS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LATS2
Gene Alias:
KPM, LATS2, Warts like kinase
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26524, 50523
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.27 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q7TSJ6, Q9NRM7
Gene Symbols:
Lats2
Immunogen:
Peptide
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Cytokeratin 7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KRT7
Gene Alias: CK 7, CK7, Cytokeratin 7, K2C7, K7, keratin 7, KRT7, Sarcolectin, SCL, Type II keratin Kb7
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110310, 300242, 3855
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.27 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P08729, Q6IG12, Q9DCV7
Gene Symbols: KRT7
Immunogen: Cytokeratin 7 Fusion Protein Ag7895
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cytokeratin 7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KRT7
Gene Alias:
CK 7, CK7, Cytokeratin 7, K2C7, K7, keratin 7, KRT7, Sarcolectin, SCL, Type II keratin Kb7
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110310, 300242, 3855
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.27 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P08729, Q6IG12, Q9DCV7
Gene Symbols:
KRT7
Immunogen:
Cytokeratin 7 Fusion Protein Ag7895
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: beta-Catenin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CTNNB1
Gene Alias: b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12387, 1499, 397657, 84353
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.23 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P35222, Q02248, Q9WU82
Gene Symbols: CTNNB1
Immunogen: Peptide
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
beta-Catenin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CTNNB1
Gene Alias:
b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12387, 1499, 397657, 84353
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.23 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P35222, Q02248, Q9WU82
Gene Symbols:
CTNNB1
Immunogen:
Peptide
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GAC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GLS
Gene Alias: AAD20, GAC, GAC-specific, GLS, GLS1, glutaminase C, K glutaminase, KIAA0838, L glutamine amidohydrolase
Host Species: Rabbit
Purification Method: Antigen Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14660, 24398, 2744
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.29 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: D3Z7P3, O94925, P13264
Gene Symbols: GLS
Immunogen: Peptide
Quantity: 150 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GAC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GLS
Gene Alias:
AAD20, GAC, GAC-specific, GLS, GLS1, glutaminase C, K glutaminase, KIAA0838, L glutamine amidohydrolase
Host Species:
Rabbit
Purification Method:
Antigen Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14660, 24398, 2744
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.29 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
D3Z7P3, O94925, P13264
Gene Symbols:
GLS
Immunogen:
Peptide
Quantity:
150 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG