50-917-180

IL-17AF Monoclonal Antibody (B8KN8R), eFluor™ 660, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-917-180-Each-of-1 In Stock ₹ 16,085.28

50-917-180 - Each of 1

₹ 16,085.28

In Stock

Quantity

1

Base Price: ₹ 16,085.28

GST (18%): ₹ 2,895.35

Total Price: ₹ 18,980.63

Antigen

IL-17AF

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q62386, Q7TNI7

Gene Symbols

Il17a, Il17f

Immunogen

Recombinant IL-17AF

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

B8KN8R

Conjugate

eFluor 660

Gene

Il17a

Gene Alias

C87042; CANDF6; Ctla8; CTLA-8; cytokine ML-1; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; IL17; IL-17; Il17a; IL-17A; IL17F; IL-17F; ILN; Interleukin; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17F; interleukin-17A; Interleukin-17F; ML1; ML-1

Host Species

Rat

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16171, 257630

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • Description: The B8KN8R monoclonal antibody reacts with mouse interleukin (IL)-17AF heterodimer
  • This antibody specifically reacts with this heterodimer and has no reactivity for IL-17A or IL-17F homodimers
  • IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells
  • Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF
  • Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis
  • Applications Reported: This B8KN8R antibody has been reported for use in intracellular staining followed by flow cytometric analysis
  • Applications Tested: This B8KN8R antibody has been tested by intracellular staining and flow cytometric analysis of Th17-polarized mouse splenocytes after restimulation with Cell stimulation Cocktail plus protein transport inhibitors, using the Intracellular Fixation & Permeabilization Buffer Set (cat
  • 88-8824) and protocol
  • Please refer to Best Protocls: Protocol A: Two step protocol for (cytoplasmic) intracellular proteins located under the Resource Tab online
  • This can be used at less than or equal to 0.125 μg per test
  • IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells
  • Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF
  • Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.

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Invitrogen

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Antigen:
IL-17AF

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q62386, Q7TNI7

Gene Symbols:
Il17a, Il17f

Immunogen:
Recombinant IL-17AF

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
B8KN8R

Conjugate:
eFluor 660

Gene:
Il17a

Gene Alias:
C87042; CANDF6; Ctla8; CTLA-8; cytokine ML-1; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; IL17; IL-17; Il17a; IL-17A; IL17F; IL-17F; ILN; Interleukin; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17F; interleukin-17A; Interleukin-17F; ML1; ML-1

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16171, 257630

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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Antigen:
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Classification:
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Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
O15392

Gene Symbols:
Birc5

Immunogen:
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Quantity:
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Primary or Secondary:
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Target Species:
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Product Type:
Antibody

Isotype:
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Applications:
Flow Cytometry

Clone:
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Conjugate:
eFluor 660

Gene:
Birc5

Gene Alias:
AAC-11; AP14; Api4; apoptosis inhibitor 4; Apoptosis inhibitor survivin; baculoviral IAP repeat containing 5; baculoviral IAP repeat-containing 5; baculoviral IAP repeat-containing 5 (survivin); baculoviral IAP repeat-containing protein 5; BIRC 5; BIRC5; EPR 1; EPR-1; Iap4; inhibitor of apoptosis; survivin; survivin variant 3 alpha; survivin40; SVV; TIAP

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
332

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4° C, store in dark, DO NOT FREEZE!

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Liquid

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Antigen:
IL-17FF (homodimer)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q96PD4

Gene Symbols:
IL17F

Immunogen:
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Quantity:
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Primary or Secondary:
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Target Species:
Human

Product Type:
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IgG2b κ

Applications:
Flow Cytometry

Clone:
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Conjugate:
eFluor 660

Gene:
IL17F

Gene Alias:
CANDF6; Cytokine ML-1; IL17F; IL-17F; ILN; Interleukin; interleukin 17F; interleukin-17F; ML1; ML-1

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
112744

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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__

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__

Target Species:
__

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__

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__