500P135BT1

TRAIL (soluble) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 500P135BT1-Each-of-1 In Stock ₹ 3,37,534.20

500P135BT1 - Each of 1

₹ 3,37,534.20

In Stock

Quantity

1

Base Price: ₹ 3,37,534.20

GST (18%): ₹ 60,756.156

Total Price: ₹ 3,98,290.356

Antigen

TRAIL (soluble)

Classification

Polyclonal

Conjugate

Biotin

Gene

TNFSF10

Gene Alias

A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8743

Content And Storage

-20°C

Applications

ELISA, Western Blot

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P50591

Gene Symbols

TNFSF10

Immunogen

E.coli-derived, 19.6 kDa Recombinant Human sTRAIL/Apo2L

Quantity

2 x 500 μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

Description

  • AA Sequence of recombinant protein: MRERGPQRVA AHITGTRGRS NTLSSPNSKN EKALGRKINS WESSRSGHSF LSNLHLRNGE LVIHEKGFYY IYSQTYFRFQ EEIKENTKND KQMVQYIYKY TSYPDPILLM KSARNSCWSK DAEYGLYSIY QGGIFELKEN DRIFVSVTNE HLIDMDHEAS FFGAFLVG
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human sTRAIL/Apo2L
  • Anti-Human sTRAIL/Apo2L-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human sTRAIL/Apo2L by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human sTRAIL/Apo2L (500-P135) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human sTRAIL/Apo2L
  • Western Blot: To detect Human sTRAIL/Apo2L by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human sTRAIL/Apo2L is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P135BT-1MG will be provided as 2 x 500 μg TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family
  • TRAIL preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues
  • TRAIL binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG
  • The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis
  • The binding of TRAIL protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3
  • Receptors for TRAIL include two death domain containing receptors, death receptor 4 (DR4) and DR5, as well as two decoy receptors, DcR1 and DcR2, lacking the intracellular signaling death domain
  • TRAIL is a type II membrane protein and expressed in a variety of human tissues
  • Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.

Compare Similar Items

Show Difference

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Fischer Scientific

500P135BT1

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Antigen:
TRAIL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF10

Gene Alias:
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8743

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P50591

Gene Symbols:
TNFSF10

Immunogen:
E.coli-derived, 19.6 kDa Recombinant Human sTRAIL/Apo2L

Quantity:
2 x 500 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Fischer Scientific

500P135BT25

--


Antigen:
TRAIL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF10

Gene Alias:
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8743

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P50591

Gene Symbols:
TNFSF10

Immunogen:
E.coli-derived, 19.6 kDa Recombinant Human sTRAIL/Apo2L

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Fischer Scientific

500P135BT50

--


Antigen:
TRAIL (soluble)

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
TNFSF10

Gene Alias:
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8743

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P50591

Gene Symbols:
TNFSF10

Immunogen:
E.coli-derived, 19.6 kDa Recombinant Human sTRAIL/Apo2L

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Fischer Scientific

500P137GBT1

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Antigen:
TWEAK

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Tnfsf12

Gene Alias:
APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8742

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O43508

Gene Symbols:
Tnfsf12

Immunogen:
E.coli-derived, 17.0 kDa Recombinant Human TWEAK

Quantity:
2 x 500 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized